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AEA-D8

AEA-D8 structure

CAS No.: 924894-98-4

Chemical Name:: AEA-D8

Synonyms: AEA-D8;ANANDAMIDE-D8;ARACHIDONOYL ETHANOLAMIDE-D8;N-(2-HYDROXYETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE-5,6,8,9,11,12,14,15-D8;(5Z,8Z,11Z,14Z)-5,6,8,9,11,12,14,15-octadeuterio-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide

CBNumber:: CB5194968

Molecular Formula:: C22H37NO2

Molecular Weight:: 347.54

MDL Number:: MFCD01632745

MOL File:: Mol file

Last updated:2023-06-08 09:03:09

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AEA-D8 Properties

solubility	1 mg/ml EtOH:PBS pH 7.2: can dilute 1:1.6 (>380 μg/ml); 10 mg/ml EtOH:PBS pH 7.2: can dilute 1:1 (>5 mg/ml) (fro; 100 ?g/ml EtOH:PBS pH 7.2: can dilute 1:1.6 (>38 μg/ml) (; DMF: >10 mg/ml (from AEA); DMSO: >30 mg/ml (from AEA); Ethanol: >100 mg/ml (from AEA); PBS pH 7.2: <100 μg/ml (from AEA)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS07

Signal word

Danger

Hazard statements

H225-H319-H336

Precautionary statements

P210-P240-P241-P242-P243-P261-P264-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P337+P313-P370+P378-P403+P233-P403+P235-P405-P501

NFPA 704

	3
2		0

AEA-D8 price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	390050	Arachidonoyl Ethanolamide-d8 ≥99% deuterated forms (d1-d8)	924894-98-4	100μg	$49	2024-03-01	Buy
Cayman Chemical	390050	Arachidonoyl Ethanolamide-d8 ≥99% deuterated forms (d1-d8)	924894-98-4	500μg	$216	2024-03-01	Buy
Cayman Chemical	390050	Arachidonoyl Ethanolamide-d8 ≥99% deuterated forms (d₁-d₈)	924894-98-4	1mg	$380	2024-03-01	Buy
Cayman Chemical	390050	Arachidonoyl Ethanolamide-d8	924894-98-4	1000μg	$304	2021-12-16	Buy
Cayman Chemical	390050	Arachidonoyl Ethanolamide-d8	924894-98-4	5000μg	$1330	2021-12-16	Buy

Product number	Packaging	Price	Buy
390050	100μg	$49	Buy
390050	500μg	$216	Buy
390050	1mg	$380	Buy
390050	1000μg	$304	Buy
390050	5000μg	$1330	Buy

AEA-D8 Chemical Properties,Uses,Production

Description

Arachidonoyl ethanolamide-d₈ (AEA-8) contains eight deuterium atoms at the 5, 6, 8, 9, 11, 12, 14, and 15 positions. It is intended for use as an internal standard for the quantification of AEA by GC- or LC-mass spectrometry. AEA is the ethanolamine amide of arachidonic acid, first isolated from porcine brain.¹ It is an endogenous cannabinoid neurotransmitter that binds to both CB₁ and CB₂ receptors.² AEA inhibits the specific binding of [³H]-HU-243 to synaptosomal membranes with a K_i value of 52 nM, compared to 46 nM for Δ⁹-THC.¹

Definition

ChEBI: Anandamide is an N-acylethanolamine 20:4 resulting from the formal condensation of carboxy group of arachidonic acid with the amino group of ethanolamine. It has a role as a neurotransmitter, a vasodilator agent and a human blood serum metabolite. It is an endocannabinoid and a N-acylethanolamine 20:4. It is functionally related to an arachidonic acid.

References

1. Devane, W.A., Hanus, L., Breuer, A., et al. Isolation and structure of a brain constituent that binds to the cannabinoid receptor Science 258(5090),1946-1949(1992).
2. Felder, C.C., Briley, E.M., Axelrod, J., et al. Anandamide, an endogenous cannabimimetic eicosanoid, binds to the cloned human cannabinoid receptor and stimulates receptor-mediated signal transduction Proc. Natl. Acad. Sci. USA 90(16),7656-7660(1993).

AEA-D8 Preparation Products And Raw materials

Raw materials

Preparation Products

AEA-D8 Suppliers

Global( 4)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
amyjetsci	027-59626688 18771149750	sales@amyjet.com	China	3004	58

Supplier	Advantage
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
amyjetsci	58

924894-98-4(AEA-D8)Related Search:

ANANDAMIDE

ARACHIDONOYL ETHANOLAMIDE-D8 ANANDAMIDE-D8 AEA-D8 N-(2-HYDROXYETHYL)-5Z,8Z,11Z,14Z-EICOSATETRAENAMIDE-5,6,8,9,11,12,14,15-D8 (5Z,8Z,11Z,14Z)-5,6,8,9,11,12,14,15-octadeuterio-N-(2-hydroxyethyl)icosa-5,8,11,14-tetraenamide 924894-98-4