ChemicalBook >> CAS DataBase List >>4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
- CAS No.
- 190728-25-7
- Chemical Name:
- 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline
- Synonyms
- Benzenam;4-(6,7-Dimethoxy-quinoL;Cabozantinib Amine Analog;Intermediate 1 of Cabozantinib;Cabozantinib Genotoxic Impurity I;4-[(6,7-dimethoxy-4-quinolinyl)oxy]-;4-(6,7-dimethoxy quinolinoxy) aniline;4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline;6,7-Dimethoxy-4-(4-aminophenoxy)quinoline;4-(4-Aminophenoxy)-6,7-dimethoxyquinoline
- CBNumber:
- CB52652846
- Molecular Formula:
- C17H16N2O3
- Molecular Weight:
- 296.32
- MDL Number:
- MFCD19685633
- MOL File:
- 190728-25-7.mol
- MSDS File:
- SDS
Last updated:2023-12-26 17:07:23
Melting point | 211.0 to 215.0 °C |
---|---|
Boiling point | 481.8±45.0 °C(Predicted) |
Density | 1.246±0.06 g/cm3 (20 ºC 760 Torr) |
storage temp. | Keep in dark place,Sealed in dry,Room Temperature |
solubility | DMSO (Slightly, Sonicated), Methanol (Slightly) |
form | powder to crystal |
pka | 6.79±0.30(Predicted) |
color | Light yellow to Brown |
InChI | InChI=1S/C17H16N2O3/c1-20-16-9-13-14(10-17(16)21-2)19-8-7-15(13)22-12-5-3-11(18)4-6-12/h3-10H,18H2,1-2H3 |
InChIKey | VXEQRXJATQUJSN-UHFFFAOYSA-N |
SMILES | C1(N)=CC=C(OC2C3C(N=CC=2)=CC(OC)=C(OC)C=3)C=C1 |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H315-H319 | |||||||||
Precautionary statements | P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313 | |||||||||
HS Code | 2933.49.7000 | |||||||||
NFPA 704 |
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4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline price More Price(12)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TCI Chemical | D5070 | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline | 190728-25-7 | 200mg | $155 | 2024-03-01 | Buy |
TCI Chemical | D5070 | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline | 190728-25-7 | 1g | $460 | 2024-03-01 | Buy |
Chem-Impex | 43936 | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline,≥98%(HPLC) ≥98%(HPLC) | 190728-25-7 | 1G | $540.8 | 2021-12-16 | Buy |
AK Scientific | J90694 | 4-(6,7-Dimethoxy-quinolin-4-yloxy)-phenylamine | 190728-25-7 | 1g | $20 | 2021-12-16 | Buy |
Ambeed | A138452 | 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline 97% | 190728-25-7 | 5g | $54 | 2021-12-16 | Buy |
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Chemical Properties,Uses,Production
Uses
4-(6,7-Dimethoxy-Quinolin-4-Yloxy)-Phenylamine is used in preparation of Cabozantinib Defluorination impurity.
Chemical Reactivity
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline is a primary alcohol that has been shown to catalyze the reaction of potassium carbonate with an alkali metal hydroxide to produce potassium. It has also been shown to be a base catalyst for the reaction of cyclopropanecarboxylic acid with an alcohol ester to produce high yield.
Synthesis of 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline from 4-chloro-6,7-dimethoxyquinoline and 4-Aminophenol
4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline Preparation Products And Raw materials
Global( 197)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Huanfu Industrial Co.,(Shanghai)Ltd. | +86-18001856580 +86-18001856580 | 2415195517@qq.com | China | 43 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 19368 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15954 | 58 |
Beijing Cooperate Pharmaceutical Co.,Ltd | 010-60279497 | sales01@cooperate-pharm.com | CHINA | 1811 | 55 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21687 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
Shandonghaohong biotechnology Co.,ltd. | 0635-6175299 13961496334 | sale@inyelchem.com | CHINA | 44 | 55 |
Anqing Chico Pharmaceutical Co., Ltd. | 15380796838 | chloewu@chicopharm.cn | CHINA | 341 | 58 |
Lianyungang happen teng technology co., LTD | 15950718863 | wang666xt@163.com | CHINA | 295 | 58 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
View Lastest Price from 4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-05-09 | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
190728-25-7
|
US $0.00-0.00 / kg | 1kg | 98% | 1 ton | Nanjing Fred Technology Co., Ltd | ||
2024-01-02 | 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
190728-25-7
|
US $200.00-1.00 / KG | 1KG | 99%, 99.5% Sublimated | g-kg-tons, free sample is available | Henan Fengda Chemical Co., Ltd | ||
2023-03-12 | BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-
190728-25-7
|
US $0.00 / kg | 1kg | 98.0%min | 100kg | LY Global chemicals co.,ltd . |
- 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
190728-25-7
- US $0.00-0.00 / kg
- 98%
- Nanjing Fred Technology Co., Ltd
- 4-[(6,7-Dimethoxyquinolin-4-yl)oxy]aniline
190728-25-7
- US $200.00-1.00 / KG
- 99%, 99.5% Sublimated
- Henan Fengda Chemical Co., Ltd
- BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-
190728-25-7
- US $0.00 / kg
- 98.0%min
- LY Global chemicals co.,ltd .
190728-25-7(4-((6,7-Dimethoxyquinolin-4-yl)oxy)aniline)Related Search:
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CAS 190728-25-7 BenzenaMine, 4-[(6,7-diMethoxy-4-quinolinyl)oxy]-
4-[(6,7-Dimethoxy-4-quinolyl)oxy]aniline
Cabozantinib Amine Analog
Benzenam
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