4-Chloro-2-iodo-benzoic acid Methyl ester
- CAS No.
- 181765-85-5
- Chemical Name:
- 4-Chloro-2-iodo-benzoic acid Methyl ester
- Synonyms
- methyl 2-iodo 4-chlorobenzoate;4-Chloro-2-iodo-benzoic acid Methyl ester;benzoic acid, 4-chloro-2-iodo-, methyl ester
- CBNumber:
- CB52671663
- Molecular Formula:
- C8H6ClIO2
- Molecular Weight:
- 296.49
- MDL Number:
- MFCD12024993
- MOL File:
- 181765-85-5.mol
- MSDS File:
- SDS
4-Chloro-2-iodo-benzoic acid Methyl ester price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | GHA76585 | Methyl 4-chloro-2-iodobenzoate | 181765-85-5 | 5g | $295 | 2026-06-04 | Buy |
| Activate Scientific | AS110218 | Methyl 4-chloro-2-iodobenzoate 97% | 181765-85-5 | 1g | $69 | 2026-06-04 | Buy |
| Activate Scientific | AS110218 | Methyl 4-chloro-2-iodobenzoate 97% | 181765-85-5 | 5g | $273 | 2026-06-04 | Buy |
| Synthonix | M48182 | Methyl 4-chloro-2-iodobenzoate 97% | 181765-85-5 | 100mg | $43 | 2026-05-06 | Buy |
| Synthonix | M48182 | Methyl 4-chloro-2-iodobenzoate 97% | 181765-85-5 | 250mg | $48 | 2026-05-06 | Buy |
4-Chloro-2-iodo-benzoic acid Methyl ester Chemical Properties,Uses,Production
Synthesis
67-56-1
13421-13-1
181765-85-5
GENERAL PROCEDURE: To a stirred solution of 4-chloro-2-iodobenzoic acid (1.0 eq.) dissolved in anhydrous methanol (2.0 mL/1.0 mmol of 4-chloro-2-iodobenzoic acid) was added sulfinyl chloride (2.0 eq.) dropwise at 0 °C. After addition, the reaction mixture was stirred at room temperature overnight. Upon completion of the reaction, the crude product was concentrated under reduced pressure, quenched with water and extracted with ethyl acetate. The organic layers were combined, washed with saturated aqueous sodium bicarbonate, dried over anhydrous sodium sulfate, concentrated by rotary evaporation, and finally purified by column chromatography to afford the target product methyl 4-chloro-2-iodobenzoate.
References
[1] Antimicrobial Agents and Chemotherapy, 2016, vol. 60, # 7, p. 3980 - 3987
[2] Patent: US2015/105351, 2015, A1. Location in patent: Paragraph 0451
[3] ACS Medicinal Chemistry Letters, 2014, vol. 5, # 11, p. 1259 - 1262
4-Chloro-2-iodo-benzoic acid Methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
4-Chloro-2-iodo-benzoic acid Methyl ester Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hunan Hui Bai Shi Biotechnology Co., Ltd. | 0731-85526065 13308475853 | ivy@hnhbsj.com | China | 7236 | 62 |
| Chiba Pharmaceutical Science and technology Co, Ltd. | 0531-81313138 13066006660 | chibapharm@foxmail.com | China | 3996 | 55 |
| SuZhou ShiYa Biopharmaceuticals, Inc. | 86(512)5235 8471 17715136450 | sales@shiyabiopharm.com | China | 4167 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Zhengzhou Guancheng Laboratory equipment Sales | 0371-88888888 qq272369594;2159423853qq | 2723695949@qq.com | China | 4991 | 50 |
| Struchem Co., Ltd. | 0512-63009836 18994340901 | helen@struchem.com | China | 3973 | 60 |
| ShangHai Wisacheam Pharmaceutical Co., Ltd. | 13817485796 | tim@wisacheampharm.com | China | 3698 | 58 |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 89667 | 60 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131885 | 58 |
| Shijiazhuang Jing Kang Technology Co.Ltd. | 13933818572 | 1519554262@qq.com | China | 1785 | 58 |
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