ChemicalBook >> CAS DataBase List >>PDE1-IN-1 (phosphate)
PDE1-IN-1 (phosphate)
- CAS No.
- 1642303-38-5
- Chemical Name:
- PDE1-IN-1 (phosphate)
- Synonyms
- ITI214;ITI-214 phosphate;PDE1-IN-1 (phosphate);Lenrispodun phosphate;ITI-214 phosphate salt;ITI-214; ITI 214; ITI214; ITI-214 PHOSPHATE SALT.;selective,oral,inhibit,motor,Phosphodiesterase (PDE),ITI 214,Inhibitor,ITI-214,cognitive,CNS-active;(6AR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one phosphate
- CBNumber:
- CB53041443
- Molecular Formula:
- C29H29FN7O5P
- Molecular Weight:
- 605.57
- MDL Number:
- MFCD28385868
- MOL File:
- 1642303-38-5.mol
Last updated:2023-06-08 09:03:02
| storage temp. | Store at -20°C |
|---|---|
| solubility | DMSO:30.0(Max Conc. mg/mL);49.54(Max Conc. mM) |
| form | A solid |
| FDA UNII | YP683YZB8K |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| NFPA 704 |
|
PDE1-IN-1 (phosphate) price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30376 | ITI214 | 1642303-38-5 | 1mg | $81 | 2024-03-01 | Buy |
| Cayman Chemical | 30376 | ITI214 | 1642303-38-5 | 10mg | $632 | 2024-03-01 | Buy |
| Cayman Chemical | 30376 | ITI214 | 1642303-38-5 | 5mg | $356 | 2024-03-01 | Buy |
| ChemScene | CS-3627 | ITI-214 99.57% | 1642303-38-5 | 10mg | $350 | 2021-12-16 | Buy |
| AK Scientific | 3885DW | (11R,15S)-5-Anilino-4-[[4-(6-fluoropyridin-2-yl)phenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one;phosphoricacid | 1642303-38-5 | 10mg | $802 | 2021-12-16 | Buy |
PDE1-IN-1 (phosphate) Chemical Properties,Uses,Production
Description
ITI214 is an inhibitor of phosphodiesterase 1 (PDE1; Ki = 0.058 nM). It is selective for PDE1 over PDE2A, -3B, -4A, -5A, -6, -7B, -8A, -9A, -10A, and -11A (Kis = 0.16-18 μM). ITI214 (3 and 6 mg/kg) enhances novel object recognition in rats. It increases prefrontal cortex cAMP and cGMP levels in mice when administered at a dose of 50 mg/kg. ITI214 (0.1, 3, and 10 mg/kg) reverses MK-801-induced decreases in spontaneous alteration in the T-maze continuous alternation task in mice.
PDE1-IN-1 (phosphate) Preparation Products And Raw materials
Raw materials
Preparation Products
PDE1-IN-1 (phosphate) Suppliers
Global( 41)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| WUHAN SUN-SHINE BIO-TECHNOLOGY Co., Ltd. | 17702719238 17702719238 | sales@sun-shinechem.com | China | 905 | 64 |
| Shanghai Topbiochem Technology Co., Ltd | 021-58170097 | info@topbiochem.com | China | 9442 | 58 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
PDE1-IN-1 (phosphate)
ITI-214; ITI 214; ITI214; ITI-214 PHOSPHATE SALT.
ITI-214 phosphate
ITI-214 phosphate salt
ITI214
(6AR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one phosphate
selective,oral,inhibit,motor,Phosphodiesterase (PDE),ITI 214,Inhibitor,ITI-214,cognitive,CNS-active
Lenrispodun phosphate
1642303-38-5