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ChemicalBook >> CAS DataBase List >> PDE1-IN-1 (phosphate)

PDE1-IN-1 (phosphate)

PDE1-IN-1 (phosphate) price.
  • $81 - $1459
  • Product name: PDE1-IN-1 (phosphate)
  • CAS: 1642303-38-5
  • MF: C29H29FN7O5P
  • MW: 605.57
  • EINECS:
  • MDL Number:MFCD28385868
  • Synonyms:PDE1-IN-1 (phosphate);ITI-214; ITI 214; ITI214; ITI-214 PHOSPHATE SALT.;ITI-214 phosphate;ITI-214 phosphate salt;ITI214;(6AR,9aS)-2-(4-(6-fluoropyridin-2-yl)benzyl)-5-methyl-3-(phenylamino)-5,6a,7,8,9,9a-hexahydrocyclopenta[4,5]imidazo[1,2-a]pyrazolo[4,3-e]pyrimidin-4(2H)-one phosphate;selective,oral,inhibit,motor,Phosphodiesterase (PDE),ITI 214,Inhibitor,ITI-214,cognitive,CNS-active;Lenrispodun phosphate
11 prices
Selected condition:
Brand
  • AK Scientific
  • Cayman Chemical
  • ChemScene
  • Crysdot
Package
  • 1mg
  • 5mg
  • 10mg
  • 50mg
  • 100mg
  • ManufacturerAK Scientific
  • Product number3885DW
  • Product description(11R,15S)-5-Anilino-4-[[4-(6-fluoropyridin-2-yl)phenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one;phosphoricacid
  • Packaging10mg
  • Price$802
  • Updated2021-12-16
  • Buy
  • ManufacturerCayman Chemical
  • Product number30376
  • Product descriptionITI214
  • Packaging1mg
  • Price$81
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number30376
  • Product descriptionITI214
  • Packaging5mg
  • Price$356
  • Updated2024-03-01
  • Buy
  • ManufacturerCayman Chemical
  • Product number30376
  • Product descriptionITI214
  • Packaging10mg
  • Price$632
  • Updated2024-03-01
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3627
  • Product descriptionITI-214 99.57%
  • Packaging5mg
  • Price$190
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3627
  • Product descriptionITI-214 99.57%
  • Packaging10mg
  • Price$350
  • Updated2021-12-16
  • Buy
  • ManufacturerChemScene
  • Product numberCS-3627
  • Product descriptionITI-214 99.57%
  • Packaging50mg
  • Price$950
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003089
  • Product descriptionITI214 98+%
  • Packaging5mg
  • Price$243
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003089
  • Product descriptionITI214 98+%
  • Packaging10mg
  • Price$347
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003089
  • Product descriptionITI214 98+%
  • Packaging50mg
  • Price$1042
  • Updated2021-12-16
  • Buy
  • ManufacturerCrysdot
  • Product numberCD31003089
  • Product descriptionITI214 98+%
  • Packaging100mg
  • Price$1459
  • Updated2021-12-16
  • Buy
Manufacturer Product number Product description Packaging Price Updated Buy
AK Scientific 3885DW (11R,15S)-5-Anilino-4-[[4-(6-fluoropyridin-2-yl)phenyl]methyl]-8-methyl-1,3,4,8,10-pentazatetracyclo[7.6.0.02,6.011,15]pentadeca-2,5,9-trien-7-one;phosphoricacid 10mg $802 2021-12-16 Buy
Cayman Chemical 30376 ITI214 1mg $81 2024-03-01 Buy
Cayman Chemical 30376 ITI214 5mg $356 2024-03-01 Buy
Cayman Chemical 30376 ITI214 10mg $632 2024-03-01 Buy
ChemScene CS-3627 ITI-214 99.57% 5mg $190 2021-12-16 Buy
ChemScene CS-3627 ITI-214 99.57% 10mg $350 2021-12-16 Buy
ChemScene CS-3627 ITI-214 99.57% 50mg $950 2021-12-16 Buy
Crysdot CD31003089 ITI214 98+% 5mg $243 2021-12-16 Buy
Crysdot CD31003089 ITI214 98+% 10mg $347 2021-12-16 Buy
Crysdot CD31003089 ITI214 98+% 50mg $1042 2021-12-16 Buy
Crysdot CD31003089 ITI214 98+% 100mg $1459 2021-12-16 Buy

Properties

storage temp. :Store at -20°C
solubility :DMSO:30.0(Max Conc. mg/mL);49.54(Max Conc. mM)
form :A solid

Safety Information

Symbol(GHS): GHS hazard pictograms
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning GHS hazard pictograms P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning GHS hazard pictograms P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning GHS hazard pictograms P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning GHS hazard pictograms
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312 IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352 IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Description

ITI214 is an inhibitor of phosphodiesterase 1 (PDE1; Ki = 0.058 nM). It is selective for PDE1 over PDE2A, -3B, -4A, -5A, -6, -7B, -8A, -9A, -10A, and -11A (Kis = 0.16-18 μM). ITI214 (3 and 6 mg/kg) enhances novel object recognition in rats. It increases prefrontal cortex cAMP and cGMP levels in mice when administered at a dose of 50 mg/kg. ITI214 (0.1, 3, and 10 mg/kg) reverses MK-801-induced decreases in spontaneous alteration in the T-maze continuous alternation task in mice.