ALLOBARBITAL
- CAS No.
- 52-43-7
- Chemical Name:
- ALLOBARBITAL
- Synonyms
- Dial;Dorm;Alnox;Malil;Curral;Diadol;Dialog;go1058;Malilum;Barbidal
- CBNumber:
- CB5349092
- Molecular Formula:
- C10H12N2O3
- Molecular Weight:
- 208.21
- MDL Number:
- MFCD00056090
- MOL File:
- 52-43-7.mol
| Melting point | 171-173° |
|---|---|
| Boiling point | 347.41°C (rough estimate) |
| Density | 1.2420 (rough estimate) |
| refractive index | 1.4830 (estimate) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 7.67±0.10(Predicted) |
| color | White to Orange |
| Water Solubility | 1.77g/L(25 ºC) |
| EWG's Food Scores | 1 |
| FDA UNII | 8NT43GG2HA |
| ATC code | N05CA21 |
| EPA Substance Registry System | 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-di-2-propen-1-yl- (52-43-7) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P264-P270-P301+P310-P321-P330-P405-P501 |
| Hazard Codes | T |
| Risk Statements | 25 |
| Safety Statements | 45 |
| RIDADR | UN 2811 6.1/PG 3 |
| WGK Germany | 3 |
| RTECS | CQ3325000 |
| HazardClass | 6.1(b) |
| PackingGroup | III |
| Toxicity | LD50 i.p. in rats: 127.3 mg/kg (Sandberg) |
ALLOBARBITAL Chemical Properties,Uses,Production
Originator
Allobarbital, Fluorochem Ltd.
Uses
Allobarbital is a barbiturate derivative that is primarily used as an anticonvulsant. Allobarbital also shows hypnotic activity and is used to boost the activity of analgesic drugs. Studies show that Allobarbital is an effective promoters of hepatocarcinogenesis. Allobarbital is a Controlled Substance.
Definition
ChEBI: Allobarbital is a member of barbiturates.
Manufacturing Process
To a mixture of 43 parts barbituric acid, 200 parts of water and 5 parts of cuprous sulfate in 10 parts of water is added 82 parts of allylbromide. Then at room temperature is added 27 parts of sodium hydroxide (10% aqueous solution). 5,5-Diallylbarbituric acid is isolated by filtration. After recrystallization from water 5,5-diallylbarbituric acid has melting polint 169- 170°C.
Therapeutic Function
Sedative, Hypnotic