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(5-Methylpyridin-3-yl)methanol

(5-Methylpyridin-3-yl)methanol Structure
(5-Methylpyridin-3-yl)methanol structure
CAS No.
102074-19-1
Chemical Name:
(5-Methylpyridin-3-yl)methanol
Synonyms
Fumarate Impurity 1;Lupatadine Impurity 5;Rupatadine impurity 3;Fumarate R Impurity 1;Rupatadine Impurity F;5-methy-3-pyridylmethanol;5-Methyl-3-pyridineMethano;Nicotine Related Compound 3;5-Methylpyridine-3-Methanol;3-methylpyridine-5-methanol
CBNumber:
CB5353437
Molecular Formula:
C7H9NO
Molecular Weight:
123.15
MDL Number:
MFCD08236816
MOL File:
102074-19-1.mol
MSDS File:
SDS
Last updated:2026-09-12 18:53:30
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(5-Methylpyridin-3-yl)methanol Properties

Boiling point 256℃
Density 1.092
Flash point 109℃
storage temp. Inert atmosphere,Room Temperature
pka 13.70±0.10(Predicted)
form liquid
color Light brown

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Risk Statements  36/37/38
Safety Statements  26-36/37/39
HS Code  2933399990

(5-Methylpyridin-3-yl)methanol price More Price(50)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth CEA07419 5-Methyl-3-pyridinemethanol 102074-19-1 10g $354 2026-06-04 Buy
Biosynth CEA07419 5-Methyl-3-pyridinemethanol 102074-19-1 100g $1180 2026-06-04 Buy
Apolloscientific OR932347 (5-Methylpyridin-3-yl)methanol 95% 102074-19-1 1g $21 2026-06-04 Buy
Apolloscientific OR932347 (5-Methylpyridin-3-yl)methanol 95% 102074-19-1 5g $64 2026-06-04 Buy
Apolloscientific OR932347 (5-Methylpyridin-3-yl)methanol 95% 102074-19-1 25g $285 2026-06-04 Buy
Product number Packaging Price Buy
CEA07419 10g $354 Buy
CEA07419 100g $1180 Buy
OR932347 1g $21 Buy
OR932347 5g $64 Buy
OR932347 25g $285 Buy

(5-Methylpyridin-3-yl)methanol Chemical Properties, Uses, Production

Synthesis

METHYL 5-METHYLNICOTINATE

29681-45-6

(5-METHYLPYRIDIN-3-YL)METHANOL

102074-19-1

Preparation of 5-methyl-3-pyridinemethanol: mix magnesium chloride, potassium borohydride and tetrahydrofuran according to the molar ratio of 2:2:1, raise the temperature to 67°C, reflux for 2 h, and then cool to room temperature to obtain solution B. Dissolve methyl 5-methylnicotinate prepared in step S1 in tetrahydrofuran, adjust the temperature to 40°C, and slowly dropwise add the solution B, and control the dropwise addition time to be completed in 1.3 hours. After the dropwise addition was completed, the reaction was continued at 40 °C for 1 hour with continuous stirring during the period. Upon completion of the reaction, it was cooled to room temperature to obtain Solution C. Methanol was added to Solution C to quench the reaction, followed by raising the temperature to 40 °C and removing the tetrahydrofuran and methanol by rotary evaporation to obtain Concentrate D. To Concentrate D, water was added and the extract was carried out with ethyl acetate for a total of three extractions. The ethyl acetate phases were combined and dried by adding anhydrous sodium sulfate to a moisture content of 0.3 wt%, filtered, and the ethyl acetate phase was taken for rotary evaporation to give the final 5-methyl-3-pyridine methanol.

References

[1] Journal of Medicinal Chemistry, 2004, vol. 47, # 25, p. 6299 - 6310
[2] Synthetic Communications, 2008, vol. 38, # 1, p. 122 - 127
[3] Patent: WO2012/97196, 2012, A1. Location in patent: Page/Page column 34
[4] Patent: EP2824103, 2015, A1. Location in patent: Paragraph 0040
[5] Patent: CN106560471, 2017, A. Location in patent: Paragraph 0055; 0061; 0067; 0073; 0079; 0085; 0091; 0096

(5-Methylpyridin-3-yl)methanol Preparation Products And Raw materials

Raw materials

Methyl 5-methylnicotinate 2-Chloro-5-methylpyridine-3-carbaldehyde Potassium borohydride Magnesium chloride Tetrahydrofuran

Preparation Products

(5-Methylpyridin-3-yl)methanol Suppliers

Global Suppliers ( 165)
Supplier Tel Email Country ProdList Advantage
Adamas Reagent, Ltd. 4006009262 13023226327 hmj@titansci.com China 14098 59
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16307 64
SpringPharma Tech Co.,Ltd +86-25-68710855, +86-25-68710897 sales@springpharma.net China 1260 62
T&W GROUP 021-61551611 13296011611 contact@trustwe.com China 9884 58
Chiba Pharmaceutical Science and technology Co, Ltd. 0531-81313138 13066006660 chibapharm@foxmail.com China 3995 55
Shanghai Topbiochem Technology Co., Ltd +86-21-60341587 sales@topbiochem.com China 6166 58
Cantotech Chemicals, Ltd. 86-0755-86635001 cantotech@126.com China 4554 55
TargetMol Chemicals Inc. 021-021-33632979 15002134094 marketing@targetmol.com China 7993 58
Quzhou Juhua Friendship Co., Ltd 0570-3066667 China 3922 58
Bide Pharmatech Ltd. 400-164-7117 18317119277 product02@bidepharm.com China 40000 60
Supplier Advantage
Adamas Reagent, Ltd. 59
Nanjing Chemlin Chemical Co., Ltd 64
SpringPharma Tech Co.,Ltd 62
T&W GROUP 58
Chiba Pharmaceutical Science and technology Co, Ltd. 55
Shanghai Topbiochem Technology Co., Ltd 58
Cantotech Chemicals, Ltd. 55
TargetMol Chemicals Inc. 58
Quzhou Juhua Friendship Co., Ltd 58
Bide Pharmatech Ltd. 60

View Latest Price from (5-Methylpyridin-3-yl)methanol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(5-METHYLPYRIDIN-3-YL)METHANOL pictures 2025-06-27 (5-METHYLPYRIDIN-3-YL)METHANOL
102074-19-1
 1KG 99% 500000kg Hebei Chuanghai Biotechnology Co., Ltd
(5-METHYLPYRIDIN-3-YL)METHANOL pictures 2025-06-20 (5-METHYLPYRIDIN-3-YL)METHANOL
102074-19-1
 $1.00-20.00 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
(5-METHYLPYRIDIN-3-YL)METHANOL pictures 2019-12-27 (5-METHYLPYRIDIN-3-YL)METHANOL
102074-19-1
 $1.00 1g 989 200kg Career Henan Chemical Co

(5-Methylpyridin-3-yl)methanol Spectrum

(5-METHYLPYRIDIN-3-YL)METHANOL(102074-19-1)1HNMR

102074-19-1 ((5-Methylpyridin-3-yl)methanol) Related Search:

Diethyl 2,6-dimethyl-3,5-pyridinedicarboxylate 5-Ethylpyridine-2,3-dicarboxylic acid 3-Pyridinemethanol Diethyl pyridine-3,5-dicarboxylate Dimethyl 4-(4-methoxyphenyl)-2,6-dimethylpyridine-3,5-dicarboxylate
2,6-Dimethyl-3,5-pyridinedicarboxylic acid 3,5-Pyridinedicarboxylic acid 6-Hydroxy-5-(2-hydroxybenzoyl)-2-(trifluoromethyl)nicotinic acid 5-Acetyl-6-hydroxy-2-methyl-nicotinic acid ethyl ester Ethyl 5-cyano-6-(methylsulfanyl)-2-phenylnicotinate
Ethyl 2-[2-(3,5-dichloroanilino)vinyl]-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate 2-Methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylic acid 2-Methyl-10-oxo-10H-9-oxa-1-aza-anthracene-3-carboxylic acid methyl ester Ethyl 2-(2-anilinovinyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate Ethyl 5-oxo-2-[2-(3-pyridinylamino)vinyl]-5H-chromeno[2,3-b]pyridine-3-carboxylate
Methyl 5-cyano-2-(dimethoxymethyl)-6-mercaptonicotinate Methyl 2-(methoxymethyl)-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate Methyl 2-ethyl-7-methyl-5-oxo-5H-chromeno[2,3-b]pyridine-3-carboxylate

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3-Pyridinemethanol,5-methyl-(6CI,9CI) 3-Hydroxymethyl-5-methylpyridine 5-Methyl-3-pyridineMethano 3-PyridineMethanol,5-Methyl- 5-methy-3-pyridylmethanol Fumarate R Impurity 1 Rupatadine impurity 3 Fumarate Impurity 1 Nicotine Related Compound 3 Piperidine,1-(3-butyn-4-yl)- Lupatadine Impurity 5 (5-Methyl-3-pyridyl)methanol 5-Methylpyridine-3-Methanol (5-Methyl-3-pyridinyl)methanol 3-methylpyridine-5-methanol Nicotine Related Compound 1 Rupatadine Impurity F (5-Methylpyridin-3-yl)methanol 102074-19-1 PYRIDINE