GALANTHAMINE HYDROBROMIDE
- CAS No.
- 69353-21-5
- Chemical Name:
- GALANTHAMINE HYDROBROMIDE
- Synonyms
- NIVALIN;nivaline;1990/4/4;NIVALIN, HBR;zocin-6-olhbr;GALANTAMINE HBR;GALANTHAMINE HBR;jilkonhydrobromide;Galantamine N-D3 HBr;Galantamine O-D3 HBr
- CBNumber:
- CB5439816
- Molecular Formula:
- C17H22BrNO3
- Molecular Weight:
- 368.27
- MDL Number:
- MFCD00067672
- MOL File:
- 69353-21-5.mol
- MSDS File:
- SDS
GALANTHAMINE HYDROBROMIDE price More Price(5)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 345670 | Galanthamine, Hydrobromide A competitive and reversible inhibitor of acetylcholinesterase. | 69353-21-5 | 20mg | $159 | 2024-03-01 | Buy |
American Custom Chemicals Corporation | INB0000936 | (-)-GALANTHAMINE HYDROBROMIDE 95.00% | 69353-21-5 | 2MG | $577.38 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | INB0000936 | (-)-GALANTHAMINE HYDROBROMIDE 95.00% | 69353-21-5 | 10MG | $748.87 | 2021-12-16 | Buy |
Crysdot | CD31001044 | Galantamine Hydrobromide 95+% | 69353-21-5 | 250mg | $170 | 2021-12-16 | Buy |
Crysdot | CD31001044 | Galantamine Hydrobromide 95+% | 69353-21-5 | 1g | $426 | 2021-12-16 | Buy |
GALANTHAMINE HYDROBROMIDE Chemical Properties,Uses,Production
General Description
A competitive and reversible inhibitor of acetylcholinesterase. Antimyasthenic agent. Can partially reverse the effects of scopolamine-induced amnesia in rats. Reported to improve learning and short-term memory in animal models.
Biochem/physiol Actions
Primary TargetAcetylcholinesterase
Clinical Use
Galantamine, which was introduced in 2001, is an alkaloid found in plants of the family Amaryllidaceae, which includes the daffodil (Narcissus pseudonarcissus) and snowflake (Leucojum aestivum). It is a reversible inhibitor of AChE, but it does not appear to inhibit butyrylcholinesterase. Because it is a tertiary amine and can cross the blood-brain barrier, it is indicated for treatment of mild-to-moderate AD and dementia. It has been used outside the U.S. for more than 30 years as an anticurare agent in anesthesia. Galantamine differs from other cholinesterase inhibitors, because it allosterically binds to nicotinic receptors, giving it a dual cholinergic action.
Metabolism
It is metabolized (75%) by CYP2D6 and CYP3A4 to afford the normethyl, O-desmethyl, and O-desmethylnormethyl metabolites, along with some other minor metabolites. Unlike tacrine, galantamine is not associated with hepatotoxicity. Its elimination half-life is 5.7 hours.
GALANTHAMINE HYDROBROMIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hong Kong Excellence Biotechnology Co., Ltd. | +86-86-18838029171 +8618126314766 | ada@sh-teruiop.com | China | 893 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
Shanghai Affida new material science and technology center | +undefined15081010295 | admin@oudaxin.com | China | 371 | 58 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21689 | 55 |
Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8615821988213 | info@longyupharma.com | China | 2531 | 58 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
View Lastest Price from GALANTHAMINE HYDROBROMIDE manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-05-25 | Galantamine Hydrobromide
69353-21-5
|
US $1.00-1900.00 / g | 1g | 99% | 100kg | Wuhan Cell Pharmaceutical Co., Ltd | ||
2024-05-23 | Galantamine Hydrobromide
69353-21-5
|
US $0.00-0.00 / kg | 1kg | 99 | 50000KG/month | Shanghai Affida new material science and technology center | ||
2024-04-25 | Galantamine hydrobromide
69353-21-5
|
US $100.00 / kg | 1kg | >99% | 20tons | Hong Kong Excellence Biotechnology Co., Ltd. |
- Galantamine Hydrobromide
69353-21-5
- US $1.00-1900.00 / g
- 99%
- Wuhan Cell Pharmaceutical Co., Ltd
- Galantamine Hydrobromide
69353-21-5
- US $0.00-0.00 / kg
- 99
- Shanghai Affida new material science and technology center
- Galantamine hydrobromide
69353-21-5
- US $100.00 / kg
- >99%
- Hong Kong Excellence Biotechnology Co., Ltd.