Calpain Substrate III, Fluorogenic - Calbiochem
- CAS No.
- Chemical Name:
- Calpain Substrate III, Fluorogenic - Calbiochem
- Synonyms
- Calpain Substrate III, Fluorogenic - Calbiochem
- CBNumber:
- CB54816941
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MOL File:
- Mol file
Calpain Substrate III, Fluorogenic - Calbiochem price More Price(1)
Calpain Substrate III, Fluorogenic - Calbiochem Chemical Properties,Uses,Production
General Description
A fluorogenic FRET peptide with a substrate sequence that is optimized for calpain-1 and -2 based on 106 known cleavage sites. It is cleaved by mammalian calpains with a much better efficacy (kcat/Kmx10-2 (M-1s-1) = 69.8, 38.5, 20.0, 6.81, 3.58, 0.05, and <0.05 for calpain-2, trypsin, papain, calpain-B, calpain-A, chymotrypsin, and cathepsin-B, respectively) and kinetically superior to other commonly used calpain substrates, such as LY-AMC and α-spectrin cleavage site-based substrate. Has been used successfully in monitoring calpain activity in whole Drosophila S2 cells (cellular incorporation achieved with a lipofection reagent) and in COS-7 cell lysate.
Biochem/physiol Actions
Product does not compete with ATP.
Calpain Substrate III, Fluorogenic - Calbiochem Preparation Products And Raw materials
Raw materials
Preparation Products
Calpain Substrate III, Fluorogenic - Calbiochem Suppliers
Global( 2)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
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Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
Supplier | Advantage |
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Sigma-Aldrich | 80 |
Calpain Substrate III, Fluorogenic - Calbiochem