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NF449

CAS No.
389142-38-5
Chemical Name:
NF449
Synonyms
NF449;NF449 OCTASODIUM SALT;NF449 - CAS 389142-38-5 - Calbiochem;1,3-Benzenedisulfonic acid, 4,4',4'',4'''-[carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakis-;4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYLIMINO)]]TETRAKIS-(BENZENE-1,3-DISULFONIC ACID, 8NA);4,4',4'',4'''-(Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino)))tetrakis-1,3-benzenedisulfonicacid,octasodium;4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid octasodium salt;4,4',4'',4'''-[CARBONYLBIS(IMINO-5,1,3-BENZENETRIYL-BIS(CARBONYLIMINO))]TETRAKIS-1,3-BENZENEDISULFONIC ACID, OCTASODIUM SALT;4,4μ,4,4μ-[Carbonylbis[imino-5,1,3-benzenetriyl bis(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid) octasodium salt;4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYL-IMINO)]]TETRAKIS(BENZENE-1,3-DISULFONIC ACID) OCTASODIUM SALT
CBNumber:
CB5764453
Molecular Formula:
C41H32N6O29S8
Molecular Weight:
1329.24
MDL Number:
MFCD03791135
MOL File:
389142-38-5.mol
Last updated:2023-04-23 13:52:06

NF449 Properties

Melting point >300°C
Density 1.991±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility H2O: soluble
form solid
pka -2.03±0.50(Predicted)
color white
Stability Hygroscopic
FDA UNII RV4PVU9V2A

SAFETY

Risk and Safety Statements

WGK Germany  3

NF449 price More Price(7)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 480420 NF449 389142-38-5 10mg $227.55 2021-12-16 Buy
Tocris 1391 NF449 389142-38-5 10 $236 2021-12-16 Buy
Tocris 1391 NF449 389142-38-5 50 $992 2021-12-16 Buy
Usbiological 165610 NF449 389142-38-5 10mg $403 2021-12-16 Buy
Usbiological 255975 NF 449 389142-38-5 10mg $489 2021-12-16 Buy
Product number Packaging Price Buy
480420 10mg $227.55 Buy
1391 10 $236 Buy
1391 50 $992 Buy
165610 10mg $403 Buy
255975 10mg $489 Buy

NF449 Chemical Properties,Uses,Production

Uses

NF449 is a known P2X1 receptor antagonist used to regulate the intravascular platelet aggregation commonly seen in systematic thromboembolism.

Biological Activity

Potent purinergic receptor antagonist that displays high selectivity for P2X 1 (IC 50 values are 0.28, 0.69, 120, 1820, 47000 and > 300000 nM for rP2X 1 , rP2X 1+5 , rP2X 2+3 , rP2X 3 , rP2X 2 and P2X 4 receptors respectively). Provides antithrombotic protection in vivo . Also acts as a G s α -selective antagonist.

NF449 Preparation Products And Raw materials

Raw materials

Preparation Products

NF449 Suppliers

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15839 69
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8447 60
Chunchuang (Wuhan) Technology Co., Ltd 15342225168 yutianchun2007@126.com China 9999 58
Shanghai Universal Biotech Co.,Ltd 13774214275 gaojun@univ-bio.com China 24990 58
United States Biological -- sales@advtechind.com United States 6075 58
4,4',4'',4'''-[CARBONYLBIS(IMINO-5,1,3-BENZENETRIYL-BIS(CARBONYLIMINO))]TETRAKIS-1,3-BENZENEDISULFONIC ACID, OCTASODIUM SALT 4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYL-IMINO)]]TETRAKIS(BENZENE-1,3-DISULFONIC ACID) OCTASODIUM SALT 4,4',4'',4'''-[CARBONYL-BIS[IMINO-5,1,3-BENZENETRIYL BIS-(CARBONYLIMINO)]]TETRAKIS-(BENZENE-1,3-DISULFONIC ACID, 8NA) NF449 NF449 OCTASODIUM SALT 4,4',4'',4'''-(Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino)))tetrakis-1,3-benzenedisulfonicacid,octasodium 4,4μ,4,4μ-[Carbonylbis[imino-5,1,3-benzenetriyl bis(carbonyl-imino)]]tetrakis(benzene-1,3-disulfonic acid) octasodium salt 4,4',4'',4'''-[Carbonylbis(imino-5,1,3-benzenetriyl-bis(carbonylimino))]tetrakis-1,3-benzenedisulfonic acid octasodium salt NF449 - CAS 389142-38-5 - Calbiochem 1,3-Benzenedisulfonic acid, 4,4',4'',4'''-[carbonylbis[imino-5,1,3-benzenetriylbis(carbonylimino)]]tetrakis- 389142-38-5 C41H24N6Na8O29S8 Purinergics P2 receptor