ChemicalBook >> CAS DataBase List >>(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN

(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN

(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN structure

CAS No.: 1000578-26-6

Chemical Name:: (2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN

Synonyms: AS 19;AS-19,AS19;(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN;(2S)-N,N-Dimethyl-5-(1,3,5-trimethyl-4-pyrazolyl)-1,2,3,4-tetrahydronaphthalen-2-amine;(S)-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydronaphthalen-2-amine;2-Naphthalenamine, 1,2,3,4-tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-, (2S)-

CBNumber:: CB5846829

Molecular Formula:: C18H25N3

Molecular Weight:: 283.41

MDL Number:: MFCD09878234

MOL File:: Mol file

Last updated:2023-07-14 17:46:14

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(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN Properties

Boiling point	413.3±45.0 °C(Predicted)
Density	1.09±0.1 g/cm3(Predicted)
storage temp.	Desiccate at -20°C
solubility	<28.34mg/ml in ethanol; <28.34mg/ml in DMSO
form	oil
pka	9.20±0.20(Predicted)
color	Yellow
FDA UNII	LA5AQ5R6QS

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02

Signal word

Danger

NFPA 704

	3
0		0

(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN price More Price(15)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Alfa Aesar	J64218	AS 19	1000578-26-6	10mg	$243	2021-12-16	Buy
Cayman Chemical	20642	AS 19	1000578-26-6	1mg	$57	2024-03-01	Buy
Cayman Chemical	20642	AS 19	1000578-26-6	10mg	$249	2024-03-01	Buy
Cayman Chemical	20642	AS 19	1000578-26-6	5mg	$193	2024-03-01	Buy
Tocris	1968	AS 19 ≥98%(HPLC)	1000578-26-6	10	$223	2021-12-16	Buy

Product number	Packaging	Price	Buy
J64218	10mg	$243	Buy
20642	1mg	$57	Buy
20642	10mg	$249	Buy
20642	5mg	$193	Buy
1968	10	$223	Buy

(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN Chemical Properties,Uses,Production

Uses

A potent 5-HT7 receptor agonist

Biological Activity

Reported potent 5-HT 7 receptor agonist (IC 50 = 0.83 nM). In vivo, enhances memory consolidation and reverses scopolamine- or dizocilpine-induced amnesia.

storage

Desiccate at -20°C

References

[1]. perez-garcía gs and meneses a. effects of the potential 5-ht7 receptor agonist as 19 in an autoshaping learning task. behav brain res, 2005, 163(1):136-40.
[2]. thomas dr and hagan jj. 5-ht7 receptors. current drug targets-cns & neurological disorders, 2004, 3(1): 81-90.
[3]. ulugol a, oltulu c, gunduz o, et al. 5-ht7 receptor activation attenuates thermal hyperalgesia in streptozocin-induced diabetic mice. pharmacol biochem behav, 2012, 102(2):344-8.
[4]. león-ponte m, ahern gp and o'connell pj. serotonin provides an accessory signal to enhance t-cell activation by signaling through the 5-ht7 receptor. blood, 2007, 109(8):3139-46.
[5]. hoffman ms and mitchell gs. spinal 5-ht7 receptor activation induces long-lasting phrenic motor facilitation. j physiol, 2011, 589(pt 6):1397-407.

(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN Preparation Products And Raw materials

Raw materials

Preparation Products

(2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN Suppliers

Global( 31)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	52927	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15848	69
VDM Biochemicals	0330-2528181	sales@vdmbio.com	United States	510	64
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8449	60
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Bejing Famous Pharmaceutical Technology Co., Ltd.	13331045123	1963319514@qq.com	China	14240	58
BOC Sciences	--	info@bocsci.com	USA	0	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Aladdin Scientific	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
VDM Biochemicals	64
EMMX Biotechnology LLC	60
Shanghai EFE Biological Technology Co., Ltd.	58
Bejing Famous Pharmaceutical Technology Co., Ltd.	58
BOC Sciences	65
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58

1000578-26-6((2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN)Related Search:

Cloxacillin-13C4 SodiuM Salt

AS 19 (2S)-(+)-5-(1,3,5-TRIMETHYLPYRAZOL-4-YL)-2-(DIMETHYLAMINO)TETRALIN 2-Naphthalenamine, 1,2,3,4-tetrahydro-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-, (2S)- (S)-N,N-dimethyl-5-(1,3,5-trimethyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydronaphthalen-2-amine AS-19,AS19 (2S)-N,N-Dimethyl-5-(1,3,5-trimethyl-4-pyrazolyl)-1,2,3,4-tetrahydronaphthalen-2-amine 1000578-26-6 Serotonin receptor Potent 5-HT7 receptor agonist.