Fmoc-N-amido-PEG5-azide
- CAS No.
- 2924480-17-9
- Chemical Name:
- Fmoc-N-amido-PEG5-azide
- Synonyms
- Fmoc-N-amido-PEG5-azide;5,8,11,14,17-Pentaoxa-2-azanonadecanoic acid, 19-azido-, 9H-fluoren-9-ylmethyl ester
- CBNumber:
- CB59621663
- Molecular Formula:
- C27H36N4O7
- Molecular Weight:
- 528.6
- MDL Number:
- MOL File:
- 2924480-17-9.mol
Fmoc-N-amido-PEG5-azide Chemical Properties, Uses, Production
Uses
Fmoc-N-amido-PEG5-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Fmoc-N-amido-PEG5-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
IC 50
PEGs
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
Fmoc-N-amido-PEG5-azide Preparation Products And Raw materials
Raw materials
Preparation Products
Fmoc-N-amido-PEG5-azide Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Xi'an Confluore Biological Technology Co., Ltd. | +86-156-80926068 +86-15680926068 | 1924344760@qq.com | China | 4229 | 58 |
| Nanjing Bairuikang Biotechnology Co., Ltd. | 18168036974 | wangweicss@126.com | China | 1379 | 58 |
| Henan Mengtai Pharmaceutical Technology Co., Ltd | 17634413542 | 1959525201@qq.com | China | 9011 | 58 |
| TargetMol | 400-821-0310 15002144251 | xuexiang.shao@tsbiochem.com | China | 29128 | 58 |
