ChemicalBook >> CAS DataBase List >>N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)

CAS No.
110025-28-0
Chemical Name:
N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture)
Synonyms
CS-2602;4OHNDtam;E/Z Endoxifen;Endoxifen (Z/E=3:2);Endoxifen(EE/Z=1:1);Endoxifen(E/Z=1: 1);(E /Z) Endoxifen HCl;Tamoxifen Impurity 16;4-hydroxy-N-desmethyltamoxifen;(E/Z)-N-desmethyl-4-hydroxy Tamoxifen
CBNumber:
CB61176584
Molecular Formula:
C25H27NO2
Molecular Weight:
373.49
MDL Number:
MFCD09840374
MOL File:
110025-28-0.mol
MSDS File:
SDS
Last updated:2023-09-04 15:50:00

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Properties

Melting point 63-72°C
Boiling point 519.3±50.0 °C(Predicted)
Density 1.099±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Chloroform, Dichloromethane, DMSO, Methanol
form Solid
pka 9.38±0.15(Predicted)
color Light Brown to Light Purple
FDA UNII 46AF8680RC

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P261-P264-P270-P271-P280-P302+P352-P304+P340-P310-P330-P361-P403+P233-P405-P501
NFPA 704
0
3 0

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 21502 (E/Z)-Endoxifen ≥98% (mixture of isomers) 110025-28-0 1mg $45 2024-03-01 Buy
Cayman Chemical 21502 (E/Z)-Endoxifen ≥98% (mixture of isomers) 110025-28-0 5mg $177 2024-03-01 Buy
Cayman Chemical 21502 (E/Z)-Endoxifen ≥98% (mixture of isomers) 110025-28-0 10mg $330 2024-03-01 Buy
Cayman Chemical 21502 (E/Z)-Endoxifen ≥98% (mixture of isomers) 110025-28-0 25mg $765 2024-03-01 Buy
TRC D292043 N-Desmethyl-4-hydroxyTamoxifen(approx.1:1E/ZMixture) 110025-28-0 25mg $580 2021-12-16 Buy
Product number Packaging Price Buy
21502 1mg $45 Buy
21502 5mg $177 Buy
21502 10mg $330 Buy
21502 25mg $765 Buy
D292043 25mg $580 Buy

N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Chemical Properties,Uses,Production

Chemical Properties

Brown Foam

Uses

A novel active metabolite of the anti-cancer drug Tamoxifen (T006000). It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line.

Uses

A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast ca

storage

Store at +4°C

611-99-4
110025-28-0
Synthesis of N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) from 4,4'-Dihydroxybenzophenone
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N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) Spectrum

4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol 4OHNDtam E/Z Endoxifen N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) 4-hydroxy-N-desmethyltamoxifen 4-[(E)-1-[4-(2-methylaminoethoxy)phenyl]-2-phenyl-but-1-enyl]phenol 4-[(Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-butenyl]phenol N-Desmethyl-4-hydroxy Tamoxifen (approx. 1:1 E/Z Mixture) see H938500 (E /Z) Endoxifen HCl Endoxifen (Z/E=3:2) 4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenylbut-1-enyl]phenol Endoxifen(EE/Z=1:1) Endoxifen(E/Z=1: 1) 4-Hydroxy-N-Desmethyl Tamoxifen ((E/Z)-Endoxifen) Phenol,4-[1-[4-[2-(methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]- CS-2602 (E/Z)-N-desmethyl-4-hydroxy Tamoxifen 4-[1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol 4-Hydroxy-N-Desmethyl Tamoxifen (Endoxifen) (Mixture of Z and E Isomers) Tamoxifen Citrate Impurity 11 (4-Hydroxy-N-Desmethyl Tamoxifen) (Mixture of Z and E Isomers) Tamoxifen Impurity 16 inhibit,Parasite,Aromatase,Endoxifen,Inhibitor,Drug Metabolite,Estrogen Receptor/ERR 110025-28-0 Aromatics Intermediates & Fine Chemicals Metabolites & Impurities Pharmaceuticals