ChemicalBook >> CAS DataBase List >>2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE
2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE
- CAS No.
- 36341-25-0
- Chemical Name:
- 2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE
- Synonyms
- Y109;Y-109;YL-109;Y-109;Y109;Phenol, 4-(2-benzothiazolyl)-2-methoxy-;4-(benzo[d]thiazol-2-yl)-2-Methoxyphenol;4-(1,3-Benzothiazol-2-yl)-2-methoxyphenol;2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE;4-(3H-1,3-benzothiazol-2-ylidene)-2-methoxycyclohexa-2,5-dien-1-one;inhibit,aryl,YL 109,hydrocarbon,AhR,antitumor,Aryl Hydrocarbon Receptor,YL109,carboxyl,breast,Hsp70-interacting,CHIP,protein,AhR,cancer,YL-109,terminus,invasiveness,Inhibitor
- CBNumber:
- CB61477104
- Molecular Formula:
- C14H11NO2S
- Molecular Weight:
- 257.31
- MDL Number:
- MFCD00030231
- MOL File:
- 36341-25-0.mol
Last updated:2023-06-08 09:03:02
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| NFPA 704 |
|
2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE price More Price(33)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 30290 | YL-109 | 36341-25-0 | 5mg | $110 | 2024-03-01 | Buy |
| Cayman Chemical | 30290 | YL-109 | 36341-25-0 | 50mg | $380 | 2024-03-01 | Buy |
| Cayman Chemical | 30290 | YL-109 | 36341-25-0 | 10mg | $195 | 2024-03-01 | Buy |
| Cayman Chemical | 30290 | YL-109 | 36341-25-0 | 25mg | $352 | 2024-03-01 | Buy |
| AK Scientific | 3261AH | 4-(Benzo[D]thiazol-2-yl)-2-methoxyphenol | 36341-25-0 | 1g | $520 | 2021-12-16 | Buy |
2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Chemical Properties,Uses,Production
Biological Activity
YL-109 is a novel antitumor agent that inhibits the growth and invasion of breast cancer cells in vitro and in vivo.
in vitro
YL-109 (0.001-10 μM; 96 h or 24 h) inhibits cell proliferation, motility, and invasiveness in breast cancer cells.
YL-109 (1 μM) increases both CHIP mRNA and protein levels in MDA-MB-231 cells.
Cell Proliferation Assay
| Cell Line: | < td class="col2"> MCF-7 and MDA-MB-231 cells|
| Concentration: | 0.001, 0.01, 0.1, 1, 10 μM |
| Incubation Time: | 96 hours |
| Result: | Strongly inhibited cell proliferation of MCF-7 and MDA-MB-231 cells in a dose-dependent manner (IC 50 =85.8 nM and 4.02 μM, respectively). |
in vivo
YL-109 (15 mg/kg; sc for every 2 d) inhibits both tumor growth and cancer metastasis of breast cancer cells in vivo.
< /p>
| Animal Model: | BALB/cAjcl-nu/nu female mice (4-5 weeks) inoculated with MCF-7 or MDA-MB-231 cells |
| Dosage: | 15 mg/kg |
| Administration: < /td> | Sc every 2 days for 63 days |
| Result: | Suppressed tumor growth in mice injected with MCF-7 and MDA-MB-231 cells. |
2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 57)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
| Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. | 025-66099280 17798518460 | cfzhang@aikonchem.com | China | 19918 | 55 |
| Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
36341-25-0(2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE)Related Search:
2-(4-HYDROXY-3-METHOXYPHENYL)BENZOTHIAZOLE
YL-109
4-(benzo[d]thiazol-2-yl)-2-Methoxyphenol
Y109
Y-109
Y-109;Y109
4-(3H-1,3-benzothiazol-2-ylidene)-2-methoxycyclohexa-2,5-dien-1-one
4-(1,3-Benzothiazol-2-yl)-2-methoxyphenol
Phenol, 4-(2-benzothiazolyl)-2-methoxy-
inhibit,aryl,YL 109,hydrocarbon,AhR,antitumor,Aryl Hydrocarbon Receptor,YL109,carboxyl,breast,Hsp70-interacting,CHIP,protein,AhR,cancer,YL-109,terminus,invasiveness,Inhibitor
36341-25-0
Inhibitors