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3-bromo-5-phenyl Salicylic Acid

CAS No.
4906-68-7
Chemical Name:
3-bromo-5-phenyl Salicylic Acid
Synonyms
NSC-109116;AKR1C1-IN-1;XVZSXNULHSIRCQ-UHFFFAOYSA-N;3-bromo-5-phenylsalicyclic acid;3-bromo-5-phenyl Salicylic Acid;3-bromo-5-phenyl Salicylic Acid Exclusive;5-Bromo-4-hydroxy[1,1'-biphenyl]-3-carboxylic acid;5-Bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid;[1,1'-Biphenyl]-3-carboxylic acid, 5-bromo-4-hydroxy-;inhibit,AKR-1C1-IN-1,progesterone,AKR1C1IN1,AKR1C1 IN 1,Inhibitor,AKR1C1
CBNumber:
CB62590019
Molecular Formula:
C13H9BrO3
Molecular Weight:
293.11
MDL Number:
MFCD16495825
MOL File:
4906-68-7.mol
MSDS File:
SDS
Last updated:2023-07-14 17:31:47

3-bromo-5-phenyl Salicylic Acid Properties

Melting point 212-214 °C
Boiling point 401.2±45.0 °C(Predicted)
Density 1.611±0.06 g/cm3(Predicted)
storage temp. Inert atmosphere,Room Temperature
solubility DMF: 15 mg/ml; DMF:PBS (pH 7.2) (1:9): 0.1 mg/ml; DMSO: 12.5 mg/ml; Ethanol: 0.1 mg/ml
form A crystalline solid
pka 2.45±0.14(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338

3-bromo-5-phenyl Salicylic Acid price More Price(19)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 123850 AKR1C1 Inhibitor, 5-PBSA - CAS 4906-68-7 - Calbiochem The AKR1C1 Inhibitor, 5-PBSA, also referenced under CAS 4906-68-7, controls the biological activity of AKR1C1. 4906-68-7 25MG $272 2024-03-01 Buy
Cayman Chemical 13574 3-bromo-5-phenyl Salicylic Acid ≥95% 4906-68-7 1mg $64 2024-03-01 Buy
Cayman Chemical 13574 3-bromo-5-phenyl Salicylic Acid ≥95% 4906-68-7 5mg $280 2024-03-01 Buy
Cayman Chemical 13574 3-bromo-5-phenyl Salicylic Acid ≥95% 4906-68-7 10mg $497 2024-03-01 Buy
Cayman Chemical 13574 3-bromo-5-phenyl Salicylic Acid ≥95% 4906-68-7 25mg $1084 2024-03-01 Buy
Product number Packaging Price Buy
123850 25MG $272 Buy
13574 1mg $64 Buy
13574 5mg $280 Buy
13574 10mg $497 Buy
13574 25mg $1084 Buy

3-bromo-5-phenyl Salicylic Acid Chemical Properties,Uses,Production

Description

The aldo-keto reductase (AKR) enzymes constitute a family of related NADPH-dependent oxidoreductases. The 1C subfamily (AKR1C) includes four human hydroxysteroid dehydrogenases, with AKR1C1 being a 20α-HSD and the other three being 3α-HSDs. AKR1C1 metabolizes progesterone to an inactive progestin, 20α-hydroxy progesterone. In addition, AKR1C1 actions have been implicated in cancer and in the processing of neuroactive steroids involved in brain function. 3-bromo-5-phenyl Salicylic acid selectively inhibits AKR1C1 (Ki = 4 nM) over AKR1C2 (Ki = 87 nM), AKR1C3 (Ki = 4.2 μM), and AKR1C4 (Ki = 18.2 μM). Moreover, it potently inhibits the metabolism of progesterone by bovine aortic endothelial cells overexpressing AKR1C1 (IC50 = 460 nM).

3-bromo-5-phenyl Salicylic Acid Preparation Products And Raw materials

Raw materials

Preparation Products

3-bromo-5-phenyl Salicylic Acid Suppliers

Global( 25)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
Tianjin Kailiqi Biotechnology Co., Ltd. 15076683720 klq@cw-bio.com China 3444 55
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Zhengzhou Alpha Chemical Co. LTD 0371-53732842 13383863444 3002612166@qq.com China 10047 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 61720 58
InvivoChem 13549236410 sales@invivochem.cn China 6712 58

4906-68-7(3-bromo-5-phenyl Salicylic Acid)Related Search:

3-bromo-5-phenyl Salicylic Acid 3-bromo-5-phenyl Salicylic Acid Exclusive XVZSXNULHSIRCQ-UHFFFAOYSA-N AKR1C1-IN-1 [1,1'-Biphenyl]-3-carboxylic acid, 5-bromo-4-hydroxy- 5-Bromo-4-hydroxy-[1,1'-biphenyl]-3-carboxylic acid NSC-109116 3-bromo-5-phenylsalicyclic acid inhibit,AKR-1C1-IN-1,progesterone,AKR1C1IN1,AKR1C1 IN 1,Inhibitor,AKR1C1 5-Bromo-4-hydroxy[1,1'-biphenyl]-3-carboxylic acid 4906-68-7