6-Chloro-2,3-dihydro-1H-indole
- CAS No.
- 52537-00-5
- Chemical Name:
- 6-Chloro-2,3-dihydro-1H-indole
- Synonyms
- NSC 87628;6-chloroindoline;6-Chloro-2,3-dihydro-1H-indole;1H-INDOLE,6-CHLORO-2,3-DIHYDRO-
- CBNumber:
- CB6263766
- Molecular Formula:
- C8H8ClN
- Molecular Weight:
- 153.61
- MDL Number:
- MFCD07371639
- MOL File:
- 52537-00-5.mol
- MSDS File:
- SDS
6-Chloro-2,3-dihydro-1H-indole price More Price(43)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Activate Scientific | AS37246-A | 6-Chloro-2,3-dihydro-1H-indole 95% | 52537-00-5 | 1g | $114 | 2026-06-04 | Buy |
| Activate Scientific | AS37246-A | 6-Chloro-2,3-dihydro-1H-indole 95% | 52537-00-5 | 5g | $300 | 2026-06-04 | Buy |
| Matrix Scientific | 292625 | 6-Chloro-2,3-dihydro-1H-indole | 52537-00-5 | 250.00mg | $44 | 2026-05-19 | Buy |
| Matrix Scientific | 292625 | 6-Chloro-2,3-dihydro-1H-indole | 52537-00-5 | 1.00g | $74 | 2026-05-19 | Buy |
| Matrix Scientific | 292625 | 6-Chloro-2,3-dihydro-1H-indole | 52537-00-5 | 5.00g | $370 | 2026-05-19 | Buy |
6-Chloro-2,3-dihydro-1H-indole Chemical Properties, Uses, Production
Synthesis
17422-33-2
52537-00-5
General procedure for the synthesis of 6-chloroindoline from 6-chloroindole: 1. reduction of indole to indoline: 6-chloro-1H-indole (2 g, 0.013 mol) was dissolved in acetic acid (10 mL) under nitrogen protection. 2. Sodium cyanoborohydride (1.24 g, 1.5 eq.) was added to the above solution and the reaction was stirred at room temperature for 20 min. 3. Upon completion of the reaction, the reaction mixture was diluted with ethyl acetate. 4. The organic phase was separated by extraction using 5N aqueous sodium hydroxide solution. 5. The organic phase was dried with magnesium sulfate, filtered and concentrated to give the crude product 6-chloro-2,3-dihydro-1H-indole (2.35 g, 116% yield). 6. The product was analyzed by material spectrum (ES, m/z): 154.0 (M + 1).
References
[1] Patent: WO2003/76398, 2003, A2. Location in patent: Page/Page column 41
[2] Patent: US2011/21500, 2011, A1. Location in patent: Page/Page column 49
[3] Patent: JP2015/193573, 2015, A. Location in patent: Paragraph 0043
[4] Patent: WO2012/143726, 2012, A1. Location in patent: Page/Page column 129
[5] Journal of Medicinal Chemistry, 2015, vol. 58, # 16, p. 6574 - 6588
6-Chloro-2,3-dihydro-1H-indole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Carbott PharmTech Inc. | 0535-6385396 | info@carbottpharm.com | China | 995 | 56 |
| Accela ChemBio Co.,Ltd. | 4000665055 | marketing@accelachem.com | China | 10972 | 64 |
| SynAsst Chemical. | 021-60343070 | China | 12731 | 55 | |
| Shanghai Raise Chemical Technology Co.,Ltd | +86-021-50935922 | China | 7854 | 55 | |
| Wulechem Co., Ltd. | 13761914825 | wulesian@wulechem.com | China | 285 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 18317119277 | product02@bidepharm.com | China | 40000 | 60 |
| Shanghai YuLue Chemical Co., Ltd. | 021-60345187 13671753212 | lzz841106@aliyun.com | China | 10244 | 55 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 18019252918 18019252918 | sale@amkchem.com | China | 14975 | 55 |
| Shanghai Yongye Biotechnology Co., Ltd. | 86-021-61559134 15921386130 | 3423497944@qq.com | China | 8135 | 55 |
| Shanghai Tombiopharma Chemical Co. Ltd. | 13391076197 | tombiopharma@163.com | China | 4986 | 55 |
View Latest Price from 6-Chloro-2,3-dihydro-1H-indole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-23 | 6-CHLORO-2,3-DIHYDRO-1H-INDOLE
52537-00-5
|
$1.00 | 100g | 99% | Career Henan Chemical Co |
-
- 6-CHLORO-2,3-DIHYDRO-1H-INDOLE
52537-00-5
- $1.00
- 99%
- Career Henan Chemical Co
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