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CHLAMYDOCIN

CHLAMYDOCIN structure

CAS No.: 53342-16-8

Chemical Name:: CHLAMYDOCIN

Synonyms: SL-3440;CHLAMYDOCIN;Antibiotic SL-3440;2-Methylcyclo[Ala-L-Phe-D-Pro-6-[(S)-2-oxo-2-oxiranylethyl]-L-Nle-];Cyclo[2-methylalanyl-L-phenylalanyl-D-prolyl-(αS,2S)-α-amino-η-oxo-2-oxiraneoctanoyl];Cyclo[2-methylalanyl-L-phenylalanyl-D-prolyl-(aS,2S)-a-amino-h-oxo-2-oxiraneoctanoyl]

CBNumber:: CB6283843

Molecular Formula:: C28H38N4O6

Molecular Weight:: 526.63

MDL Number:: MFCD31380760

MOL File:: 53342-16-8.mol

Last updated:2023-06-08 09:03:00

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CHLAMYDOCIN Properties

Boiling point	861.8±65.0 °C(Predicted)
Density	1.27±0.1 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMSO: soluble; Ethanol: soluble; Methanol: soluble
form	A solid
pka	13.36±0.70(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302+H312+H332-H315-H319-H335

Precautionary statements

P260-P280-P312

HS Code

29419000

NFPA 704

	0
3		0

CHLAMYDOCIN price More Price(2)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	28468	Chlamydocin	53342-16-8	1mg	$396	2024-03-01	Buy
TRC	C292200	Chlamydocin	53342-16-8	10mg	$1320	2021-12-16	Buy

Product number	Packaging	Price	Buy
28468	1mg	$396	Buy
C292200	10mg	$1320	Buy

CHLAMYDOCIN Chemical Properties,Uses,Production

Description

Chlamydocin is a histone deacetylase (HDAC) inhibitor that was originally isolated from D. chlamydosporia and has anticancer properties. It is selective for HDAC1 over HDAC6 (IC₅₀ = 0.15 and 1,100 nM, respectively). Chlamydocin increases acetylation of histone H3 and histone H4 in A2780 cells when used at concentrations ranging from 1 to 1,000 nM. It inhibits growth of A2780, Malme-3M, MCF-7, HT-29, and HeLa cancer cells (IC₅₀s = 0.36, 45, 5.3, 4.3, and 14 nM, respectively). Chlamydocin increases lifespan by 10% in a P185 mouse allograft model when administered at doses ranging from 20 to 160 mg/kg.

Uses

Chlamydocin is a cyclic tetrapeptide and an irreversible histone deacetylase (HDAC) inhibitor.

CHLAMYDOCIN Preparation Products And Raw materials

Raw materials

Preparation Products

CHLAMYDOCIN Suppliers

Global( 21)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	CHINA	52867	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	50002	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14059	65
Beijing Jin Ming Biotechnology Co., Ltd.	010-60605840 18892239720	psaitong@jm-bio.com	China	12308	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
Zhejiang Huida Biotech Co., LTD	0571-89903882 13626641628	jiangnan@huidabiotech.com	China	3659	58
Changzhou Furuisi Biotechnology Co., Ltd	0519-85524369	3477467573@qq.com	China	8618	58
TCI (Shanghai) Chemical Trading Co., Ltd.	021-61109150	sales@tcisct.com	China	31163	58

Supplier	Advantage
Dayang Chem (Hangzhou) Co.,Ltd.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
GIHI CHEMICALS CO.,LIMITED	58
BOC Sciences	65
Beijing Jin Ming Biotechnology Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
Zhejiang Huida Biotech Co., LTD	58
Changzhou Furuisi Biotechnology Co., Ltd	58
TCI (Shanghai) Chemical Trading Co., Ltd.	58

53342-16-8(CHLAMYDOCIN)Related Search:

Cyclen CHLAMYDOCIN

Cyclo[2-methylalanyl-L-phenylalanyl-D-prolyl-(aS,2S)-a-amino-h-oxo-2-oxiraneoctanoyl] CHLAMYDOCIN 2-Methylcyclo[Ala-L-Phe-D-Pro-6-[(S)-2-oxo-2-oxiranylethyl]-L-Nle-] Antibiotic SL-3440 SL-3440 Cyclo[2-methylalanyl-L-phenylalanyl-D-prolyl-(αS,2S)-α-amino-η-oxo-2-oxiraneoctanoyl] 53342-16-8 C28H38N4O6 Antibiotic