Cefodizime
- CAS No.
- 69739-16-8
- Chemical Name:
- Cefodizime
- Synonyms
- FIR-221;Estrofan;Cefodizim;Cefodizme;CEFODIZIME;Cefodizime,CDZM;CefodizMe SodiuM;Sodium cefodizime;CEFODIZIME FREE ACID;Cefodizime USP/EP/BP
- CBNumber:
- CB6299020
- Molecular Formula:
- C20H20N6O7S4
- Molecular Weight:
- 584.67
- MDL Number:
- MFCD00864926
- MOL File:
- 69739-16-8.mol
Melting point | >170°C (dec.) |
---|---|
alpha | D25 -55.9° |
Density | 1.86±0.1 g/cm3(Predicted) |
storage temp. | -20°C Freezer |
solubility | DMSO (Slightly), Methanol (Slightly, Heated) |
form | Solid |
pka | pK1 2.85; pK2 3.37; pK3 4.18(at 25℃) |
color | White to Off-White |
CAS DataBase Reference | 69739-16-8(CAS DataBase Reference) |
FDA UNII | Z31298J4HQ |
ATC code | J01DD09 |
SAFETY
Risk and Safety Statements
Hazard Codes | Xi |
---|---|
Risk Statements | 36/37/38-42/43 |
Safety Statements | 22-26-36/37/39 |
Cefodizime price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
TRC | C242865 | Cefodizime | 69739-16-8 | 25mg | $50 | 2021-12-16 | Buy |
TRC | C242865 | Cefodizime | 69739-16-8 | 1g | $120 | 2021-12-16 | Buy |
ChemScene | CS-0028575 | Cefodizime ≥97.0% | 69739-16-8 | 50mg | $80 | 2021-12-16 | Buy |
ChemScene | CS-0028575 | Cefodizime ≥97.0% | 69739-16-8 | 100mg | $110 | 2021-12-16 | Buy |
AK Scientific | K170 | Cefodizime | 69739-16-8 | 25mg | $38 | 2021-12-16 | Buy |
Cefodizime Chemical Properties,Uses,Production
Chemical Properties
Cefodizime Sodium is a white to light yellowish white crystalline powder. It has no odor or a slightly peculiar odor and has a bitter taste. It is highly soluble in water (around 270g/L) but only sparingly soluble in ethanol or ether.
Uses
Cefodizime is a third generation cephalosporin with a broad spectrum of antibacterial activity. Cefodizime maybe useful in the treatment of otitis media, sinusitis and gynaecological infections, and for the prophylaxis or treatment of surgical infections.
Definition
ChEBI: Cefodizime is a cephalosporin compound having 5-(carboxymethyl)-4-methyl-1,3-thiazol-2-yl]sulfanyl}methyl and [2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetyl]amino side groups located at positions 3 and 7 respectively. It has a role as an antibacterial drug and an EC 1.14.18.1 (tyrosinase) inhibitor. It is a cephalosporin, a member of 1,3-thiazoles and an oxime O-ether.
Preparation
The synthesis of cefodizime involved the following steps:
Dissolve 6.1g of (2-mercapto-4-methylthiazol-5-yl) acetic acid in water and adjust the pH to 6.5 by adding 2 mol/L sodium hydroxide.
Heat the solution to 70°C and then add a solution of 12g of cefotaxime in 75ml of water with stirring.
Keep stirring the mixture at 70°C for 3 hours while maintaining the pH at 6.5 by adding 2 mol/L sodium hydroxide.
Cool the mixture to room temperature and acidify it to pH 2.8.
Filter the resulting precipitate and wash it with water.
Dry the precipitate under vacuum and in the presence of phosphorus pentoxide.
As a result, 10g of cefodizime is obtained.
Cefodizime, an aminothiazolylcephalosporin. V. Synthesis and structure-activity relationships in the cefodizime series. DOI: 10.7164/antibiotics.40.29
Cefodizime Preparation Products And Raw materials
Raw materials
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Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Hebei Mojin Biotechnology Co., Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12446 | 58 |
Shanghai Yingrui Biopharma Co., Ltd. | +86-21-33585366 - 03@ | sales03@shyrchem.com | CHINA | 738 | 60 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8820 | 58 |
Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29823 | 58 |
SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
Hebei Runbin Biotechnology Co. LTD | 13180553332 | 2179877681@qq.com | CHINA | 996 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 |
View Lastest Price from Cefodizime manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-18 | Cefodizime
69739-16-8
|
US $0.00-0.00 / Kg/Drum | 1KG | 98%min | 1000kg | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-04-28 | Cefodizime
69739-16-8
|
US $5.00 / kg | 1kg | 99.92% | 50000tons | Ouhuang Engineering Materials (Hubei) Co., Ltd | ||
2023-08-15 | Cefodizime
69739-16-8
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd |
- Cefodizime
69739-16-8
- US $0.00-0.00 / Kg/Drum
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- Cefodizime
69739-16-8
- US $5.00 / kg
- 99.92%
- Ouhuang Engineering Materials (Hubei) Co., Ltd
- Cefodizime
69739-16-8
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
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