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FzM1

FzM1 structure

CAS No.: 1680196-54-6

Chemical Name:: FzM1

Synonyms: FzM1;FzM1 >=98% (HPLC);FzM1 (Fzd4 modulator FzM1;N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-urea;Urea, N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-

CBNumber:: CB63152616

Molecular Formula:: C21H16N2O2S

Molecular Weight:: 360.43

MDL Number:: MFCD29079017

MOL File:: 1680196-54-6.mol

Last updated:2023-09-04 15:51:00

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FzM1 Properties

Boiling point	518.3±50.0 °C(Predicted)
Density	1.401±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 12 mg/ml; DMF:PBS (pH 7.2)(1:3): 0.2 mg/ml; DMSO: 10 mg/ml
form	A crystalline solid
pka	9.42±0.10(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

NFPA 704

	0
2		0

FzM1 price More Price(5)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	19074	FzM1 ≥95%	1680196-54-6	500μg	$37	2024-03-01	Buy
Cayman Chemical	19074	FzM1 ≥95%	1680196-54-6	1mg	$68	2024-03-01	Buy
Cayman Chemical	19074	FzM1 ≥95%	1680196-54-6	5mg	$118	2024-03-01	Buy
AK Scientific	SYN5597	FzM1	1680196-54-6	10mg	$160	2021-12-16	Buy
AK Scientific	SYN5597	FzM1	1680196-54-6	50mg	$547	2021-12-16	Buy

Product number	Packaging	Price	Buy
19074	500μg	$37	Buy
19074	1mg	$68	Buy
19074	5mg	$118	Buy
SYN5597	10mg	$160	Buy
SYN5597	50mg	$547	Buy

FzM1 Chemical Properties,Uses,Production

Description

Wnt signaling proteins are small secreted proteins that are active in embryonic development, tissue homeostasis, and tumorigenesis. Wnt proteins initiate cell signaling by binding Frizzled (Fz) receptors, a family of G protein-coupled receptors. FzM1 is an allosteric ligand of Fz4. At 10 μM, it inhibits nuclear translocation of β-catenin in U87MG glioma cells treated with lithium chloride, a GSK3 inhibitor that enhances the Wnt canonical signaling pathway. FzM1 impairs the ability of U87MG cells to form neurospheres in culture and stimulates the differentiation of Caco-2 epithelial colorectal adenocarcinoma cells.

FzM1 Preparation Products And Raw materials

Raw materials

Preparation Products

FzM1 Suppliers

Global( 17)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	86-571-88216897,88216896 13588875226	sales@hzclap.com	CHINA	6313	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2982	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	18818260767	sales@chemegen.com	China	11289	58
ShangHai ChuanQian Chemcial Technique Centre	15869524721	3525679403@qq.com	China	3762	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44894	58
MedBioPharmaceutical Technology Inc	021-69568360 18916172912	order@med-bio.cn	China	8141	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
HANGZHOU CLAP TECHNOLOGY CO.,LTD	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Rechem science Co., Ltd.	58
Shanghai Hongye Biotechnology Co. Ltd	58
ChemeGen(Shanghai) Biotechnology Co.,Ltd.	58
ShangHai ChuanQian Chemcial Technique Centre	58
Energy Chemical	58
MedBioPharmaceutical Technology Inc	58

FzM1 Spectrum

FzM1(1680196-54-6)¹HNMR

FzM1 FzM1 (Fzd4 modulator FzM1 FzM1 >=98% (HPLC) Urea, N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl- N-[3-hydroxy-5-(2-thienyl)phenyl]-N'-2-naphthalenyl-urea 1680196-54-6