Dynorphin A (1-13)
- CAS No.
- 72957-38-1
- Chemical Name:
- Dynorphin A (1-13)
- Synonyms
- Dyn(1-13);YGGFLRRIRPKLK;DYNORPHIN 1-13;DYNORPHIN A (1-13);sh-Oligopeptide-71;Dynorphin A1-13【pig】;Dynorphin A(1-13)【pig】;Dynorphin A(1-13)【rat】;DYNORPHIN A(HUMAN, 1-13);Dynphin A (1-13) Acetate
- CBNumber:
- CB6699152
- Molecular Formula:
- C75H126N24O15
- Molecular Weight:
- 1603.95
- MDL Number:
- MFCD00076366
- MOL File:
- 72957-38-1.mol
Density | 1.39±0.1 g/cm3(Predicted) |
---|---|
RTECS | JV7436666 |
storage temp. | Inert atmosphere,Store in freezer, under -20°C |
form | Solid |
pka | 3.31±0.10(Predicted) |
color | White to off-white |
Water Solubility | Water: ≥ 60 mg/mL (37.41 mM) |
Sequence | H-Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-OH |
InChIKey | OVVIBUHLQIYUEU-JASZZEBFNA-N |
FDA UNII | VFC23V742Z |
Dynorphin A (1-13) price More Price(20)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | D7017 | Dynorphin A Porcine Fragment 1-13 ≥97% (HPLC) | 72957-38-1 | 1mg | $190 | 2024-03-01 | Buy |
Alfa Aesar | J64015 | Dynorphin A (1-13), porcine | 72957-38-1 | 1mg | $54.3 | 2023-06-20 | Buy |
Alfa Aesar | J64015 | Dynorphin A (1-13), porcine | 72957-38-1 | 5mg | $219 | 2023-06-20 | Buy |
Apolloscientific | BISN0009 | PorcineDynorphinA(1-13) 99% | 72957-38-1 | 5mg | $225 | 2021-12-16 | Buy |
AK Scientific | 9669AJ | DynorphinA(1-13) | 72957-38-1 | 5mg | $207 | 2021-12-16 | Buy |
Dynorphin A (1-13) Chemical Properties,Uses,Production
Description
Dynorphin A(1-13), a tridecapeptide of the endogenous opioid peptides, has modest effects in reducing mild opiate withdrawal in humans. Previous studies revealed that dynorphin also potentiates the analgesic effect of morphine in morphine-tolerant rats and mice. The therapeutic potential of dynorphin A(1-13) is limited due to extensive metabolism by human metabolic enzymes resulting in an in vivo half-life of less than one minute. Chemical modifications of dynorphin A(1-13), such as N-methylation of Tyr1 and amidation of the C-terminus have been shown to be effective in protecting against the proteolytic enzymes in human plasma[1].
Application
Dynorphin A (1-13) has been used as a test compound in the field asymmetric waveform ion mobility spectrometry coupled to mass spectrometry (FAIMS/IMS/MS).
Biochem/physiol Actions
Dynorphin A (1-13), a bioactive product of dynorphin A displays interaction with N-methyl- D-aspartate (NMDA) as well as with opioid receptors. It elevates intracellular calcium [Ca2+]i level and contributes to the loss of neurons affecting neuronal viability.
References
[1] B BRUGOS; G H. Metabolism of dynorphin A(1-13).[J]. Pharmazie, 2004.
Dynorphin A (1-13) Preparation Products And Raw materials
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
Henan Bao Enluo International TradeCo.,LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
Apextide Co Ltd | +86-15300650552 +86-15300650552 | info@apextide.com | China | 71 | 58 |
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 10991 | 58 |
Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
Hangzhou Hyper Chemicals Limited | +86-0086-57187702781 +8613675893055 | info@hyper-chem.com | China | 295 | 58 |
Alpha Biopharmaceuticals Co., Ltd | +86-15542445688 | sales@alabiochem.com | China | 888 | 58 |
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29888 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
View Lastest Price from Dynorphin A (1-13) manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-09-18 | Dynorphin A (1-13)
72957-38-1
|
US $0.00 / g | 1g | 98%min | 1000g | WUHAN FORTUNA CHEMICAL CO., LTD | ||
2024-08-27 | Dynorphin A (1-13)
72957-38-1
|
US $75.00-750.00 / kg | 10kg | 0.99 | 20tons | Zibo Hangyu Biotechnology Development Co., Ltd | ||
2024-08-26 | Dynorphin A (1-13)
72957-38-1
|
US $0.00-0.00 / Gram | 1Gram | 99%, USP, EP | 100KG | Hangzhou Hyper Chemicals Limited |
- Dynorphin A (1-13)
72957-38-1
- US $0.00 / g
- 98%min
- WUHAN FORTUNA CHEMICAL CO., LTD
- Dynorphin A (1-13)
72957-38-1
- US $75.00-750.00 / kg
- 0.99
- Zibo Hangyu Biotechnology Development Co., Ltd
- Dynorphin A (1-13)
72957-38-1
- US $0.00-0.00 / Gram
- 99%, USP, EP
- Hangzhou Hyper Chemicals Limited
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