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ChemicalBook >> CAS DataBase List >>1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Structure
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE structure
CAS No.
84477-87-2
Chemical Name:
1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE
Synonyms
H-7;H-72HCl;H-7 inhibitor;Protein kinase inhibitor H-7;1-(5-Isoquinolylsulfonyl)-2-methylpiperazine;1-(5-isoquinolinesulfonyl)-2-methylpiperazine;Isoquinoline-5-sulfonic 2-methyl-1-piperazide;5-(2-methylpiperazine-1-sulfonyl)isoquinoline;5-(2-methylpiperazin-1-yl)sulfonylisoquinoline;1-(5-isoquinolinylsulfonyl)-2-methyl-piperazin
CBNumber:
CB6719627
Molecular Formula:
C14H17N3O2S
Molecular Weight:
291.37
MDL Number:
MFCD00063403
MOL File:
84477-87-2.mol
Last updated:2023-05-18 11:31:18
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1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Properties

Boiling point 495.3±55.0 °C(Predicted)
Density 1.277±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility ethanol: 20 mg/mL
pka 7.69±0.40(Predicted)
BRN 5482740
FDA UNII 487H9Q0F9N

SAFETY

Risk and Safety Statements

WGK Germany  3
RTECS  TL9305000
F  10
Toxicity LD50 intravenous in mouse: 94mg/kg

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich I6891 H-7 84477-87-2 25mg $1060 2024-03-01 Buy
Sigma-Aldrich I6891 H-7 84477-87-2 5mg $324 2023-06-20 Buy
American Custom Chemicals Corporation KIN0000366 H-7 95.00% 84477-87-2 10MG $653.68 2021-12-16 Buy
American Custom Chemicals Corporation KIN0000366 H-7 95.00% 84477-87-2 50MG $1012.65 2021-12-16 Buy
Chemenu CM229708 5-((2-Methylpiperazin-1-yl)sulfonyl)isoquinoline 97% 84477-87-2 1g $729 2021-12-16 Buy
Product number Packaging Price Buy
I6891 25mg $1060 Buy
I6891 5mg $324 Buy
KIN0000366 10MG $653.68 Buy
KIN0000366 50MG $1012.65 Buy
CM229708 1g $729 Buy

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Chemical Properties,Uses,Production

Definition

ChEBI: A member of the class of N-sulfonylpiperazines that is 2-methylpiperazine substituted at position 1 by a 5-isoquinolinesulfonyl group.

Biological Activity

Protein kinase inhibitor. IC 50 values for inhibition of PKC, PKG, PKA and myosin light chain kinase are 6.0, 5.8, 3.0 and 97.0 μ M respectively.

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Preparation Products And Raw materials

Raw materials

Preparation Products

1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE Suppliers

Global( 45)Suppliers
Supplier Tel Email Country ProdList Advantage
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Shanghaizehan biopharma technology co., Ltd. 021-61350663 13052117465 sales@zehanbiopharma.com China 991 55
EMMX Biotechnology LLC 888-539-0666 info@emmx.com United States 8449 60
ShangHai Biochempartner Co.,Ltd 17754423994 17754423994 2853530910@QQ.com China 8011 62
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9440 58
DC Chemicals 021-58447131 13564518121 sales@dcchemicals.com China 9414 58
InvivoChem 13549236410 sales@invivochem.cn China 6712 58
Shanghai Maclean Biochemical Technology Co., LTD 021-50706066 15221275939 shenlinxing@macklin.cn China 29803 58
Supplier Advantage
ATK CHEMICAL COMPANY LIMITED 		60
Aladdin Scientific 		58
3B Pharmachem (Wuhan) International Co.,Ltd. 69
Shanghaizehan biopharma technology co., Ltd. 55
EMMX Biotechnology LLC 60
ShangHai Biochempartner Co.,Ltd 62
Shanghai Chaolan Chemical Technology Center 58
DC Chemicals 58
InvivoChem 58
Shanghai Maclean Biochemical Technology Co., LTD 58

84477-87-2(1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE)Related Search:

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1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE (S)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE DIHYDROCHLORIDE (R)-4-(Isoquinoline-5-sulfonyl)-3-methyl-piperazine-1-carboxylic acid tert-butyl ester dihydrochloride

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1-(5-isoquinolinesulfonyl)-2-methylpiperazine 1-(5-isoquinolinylsulfonyl)-2-methyl-piperazin 1-(5-ISOQUINOLINYLSULFONYL)-2-METHYL-PIPERAZINE 1-(5-isoquinolinylsulfonyl)-2-*methylpiperazine F 1-(5-ISOQUINOLINYLSULFONYL)-2-*METHYLPIP ERAZINE FRE H-72HCl 1-(5-Isoquinolinesulfonyl)-2-methylpiperazine, Isoquinoline-5-sulfonic 2-methyl-1-piperazide (Isoquinoline-5-yl)(2-methylpiperazine-1-yl) sulfone 1-(5-Isoquinolylsulfonyl)-2-methylpiperazine 5-(2-methylpiperazin-1-yl)sulfonylisoquinoline Isoquinoline-5-sulfonic 2-methyl-1-piperazide 5-[(2-methyl-1-piperazinyl)sulfonyl]Isoquinoline 5-(2-methylpiperazine-1-sulfonyl)isoquinoline H-7 Isoquinoline, 5-[(2-methyl-1-piperazinyl)sulfonyl]- Protein kinase inhibitor H-7 H-7 inhibitor 84477-87-2 Cell Biology Cell Signaling and Neuroscience BioChemical Kinase/Phosphatase Biology Protein kinase A and protein kinase C (PKA and PKC) Serine/Threonine Kinase Inhibitors