ChemicalBook >> CAS DataBase List >>K-strophanthin-beta

K-strophanthin-beta

CAS No.
560-53-2
Chemical Name:
K-strophanthin-beta
Synonyms
Nsc4320;STROPHANTHIN;K-strophanthin-beta;.beta.-K-Strophanthin;Strophanthin K (crystalline);.beta.-Strophanthobioside, strophanthidin-3;3β-[(4-O-β-D-Glucopyranosyl-3-O-methyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β-card-20(22)-enolide;(3β,5β)-3-{[2,6-dideoxy-4-O-(β-D-glucopyranosyl)-3-O-methyl-β-D-ribo-hexopyranosyl]oxy}-5,14-dihydroxy-19-oxocard-20(22)-enolide;Card-20(22)-enolide, 3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-xylo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)-;5.beta.-Card-20(22)-enolide, 3.beta.-[(2,6-dideoxy-4-o-.beta.-D-glucopyranosyl-3-o-methyl-.beta.-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-
CBNumber:
CB72130870
Molecular Formula:
C36H54O14
Molecular Weight:
710.81
MDL Number:
MOL File:
560-53-2.mol
Last updated:2023-05-04 17:34:40

K-strophanthin-beta Properties

Melting point 195°C
Boiling point 628.39°C (rough estimate)
Density 1.1625 (rough estimate)
refractive index 1.6130 (estimate)
pka 12.89±0.70(Predicted)
FDA UNII K935S3T1OE

K-strophanthin-beta Chemical Properties,Uses,Production

Description

Strophanthin is made up of a mixture of glycosides, mainly K-strophanthin- β, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-D-cymaro-β-D-glycoside, and K-strophanthoside, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-Dcymaro- β-D-gluco-α-D-glycozide. It is isolated primarily from the family Strophantus kombe.

Uses

Strophanthin is used in severe cardiovascular insufficiency, in particular after myocardial infarction, for chronic cardiac insufficiency, cardiac decompensation, supraventricular tachycardia, and ventricular arrhythmia.

Definition

ChEBI: K-Strophanthin-beta is a cardenolide glycoside and a steroid aldehyde.

K-strophanthin-beta Preparation Products And Raw materials

Raw materials

Preparation Products

STROPHANTHIN K-strophanthin-beta 3β-[(4-O-β-D-Glucopyranosyl-3-O-methyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β-card-20(22)-enolide .beta.-K-Strophanthin .beta.-Strophanthobioside, strophanthidin-3 5.beta.-Card-20(22)-enolide, 3.beta.-[(2,6-dideoxy-4-o-.beta.-D-glucopyranosyl-3-o-methyl-.beta.-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo- Card-20(22)-enolide, 3-[(2,6-dideoxy-4-o-.beta.-D-glucopyranosyl-3-o-methyl-.beta.-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3.beta.,5.beta.)- Nsc4320 Strophanthin K (crystalline) (3β,5β)-3-{[2,6-dideoxy-4-O-(β-D-glucopyranosyl)-3-O-methyl-β-D-ribo-hexopyranosyl]oxy}-5,14-dihydroxy-19-oxocard-20(22)-enolide Card-20(22)-enolide, 3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-xylo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)- 560-53-2