10-(1,3-Benzodioxol-5-yl)furo[3',4':6,7]naphtho[1,2-d]-1,3-dioxol-7(9H)-one
![10-(1,3-Benzodioxol-5-yl)furo[3',4':6,7]naphtho[1,2-d]-1,3-dioxol-7(9H)-one Structure](CAS/GIF/18920-47-3.gif)
- CAS No.
- 18920-47-3
- Chemical Name:
- 10-(1,3-Benzodioxol-5-yl)furo[3',4':6,7]naphtho[1,2-d]-1,3-dioxol-7(9H)-one
- Synonyms
- CS-1215;ACH126447;Helioxanthin;Helioxanthin, ACH 126447;10-(1,3-Benzodioxol-5-yl)furo[3',4':6,7]naphtho[1,2-d]-1,3-dioxol-7(9H)-one;Furo[3',4':6,7]naphtho[1,2-d]-1,3-dioxol-7(9H)-one, 10-(1,3-benzodioxol-5-yl)-
- CBNumber:
- CB72216774
- Molecular Formula:
- C20H12O6
- Molecular Weight:
- 348.31
- MDL Number:
- MFCD28167790
- MOL File:
- 18920-47-3.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
10-(1,3-Benzodioxol-5-yl)furo[3',4':6,7]naphtho[1,2-d]-1,3-dioxol-7(9H)-one price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ApexBio Technology | B4699 | Helioxanthin | 18920-47-3 | 5mg | $383 | 2021-12-16 | Buy |
| ChemScene | CS-3196 | Helioxanthin >98.0% | 18920-47-3 | 10mg | $500 | 2021-12-16 | Buy |
| ApexBio Technology | B4699 | Helioxanthin | 18920-47-3 | 10mg | $549 | 2021-12-16 | Buy |
| ChemScene | CS-3196 | Helioxanthin >98.0% | 18920-47-3 | 5mg | $350 | 2021-12-16 | Buy |
| CSNpharm | CSN18061 | Helioxanthin | 18920-47-3 | 10mg | $350 | 2021-12-16 | Buy |
10-(1,3-Benzodioxol-5-yl)furo[3',4':6,7]naphtho[1,2-d]-1,3-dioxol-7(9H)-one Chemical Properties,Uses,Production
Definition
ChEBI: Helioxanthin is a furonaphthodioxole that is furo[3',4':6,7]naphtho[1,2-d][1,3]dioxol-7(9H)-one substituted by a 1,3-benzodioxol-5-yl group at posiiton 10. It is a inhibitor of HBV, HCV and HSV-1 viruses. It has a role as an anti-HBV agent, a plant metabolite and an antineoplastic agent. It is a member of benzodioxoles, a furonaphthodioxole and a lignan.
Biological Activity
helioxanthin (ach126447) is a novel inhibitor of hbv, hcv and hsv-1 virus with ec50 values of 1 μm, 3 μm and 2 μm, respectively [1].helioxanthin has shown significant antiviral effect on hbv, hcv and hsv-1 virus in vitro with ec50 values of 1 μm, 3 μm and 2 μm, respectively. in a cell culture model, the level of hbv rna, the expression of hbv antigen and its replication were all reduced by helioxanthin. besides, helioxanthin has been exhibited to have a low cytotoxicity on both mt-223 and cem24 cell lines with id50 values of 2.5 μm and 31 μm, respectively [1].
References
[1] yeo h1, li y, fu l, zhu jl, gullen ea, dutschman ge, lee y, chung r, huang es, austin dj, cheng yc. synthesis and antiviral activity of helioxanthin analogues. j med chem. 2005 jan 27;48(2):534-46.
10-(1,3-Benzodioxol-5-yl)furo[3',4':6,7]naphtho[1,2-d]-1,3-dioxol-7(9H)-one Preparation Products And Raw materials
Raw materials
Preparation Products
10-(1,3-Benzodioxol-5-yl)furo[3',4':6,7]naphtho[1,2-d]-1,3-dioxol-7(9H)-one Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
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| Angel Pharmatech, Ltd. | 17317130613 | 3358272972@qq.com | China | 3246 | 58 |