TERRESTRIN A
- CAS No.
- 858134-23-3
- Chemical Name:
- TERRESTRIN A
- Synonyms
- VIALININ A;TERRESTRIN A;NOJUKCRPSUMHQQ-UHFFFAOYSA-N;1,1'-(4,4'',5',6'-Tetrahydroxy[1,1':4',1''-terphenyl]-2',3'-diyl) benzeneacetic acid ester;Benzeneacetic acid, 1,1'-(4,4'',5',6'-tetrahydroxy[1,1':4',1''-terphenyl]-2',3'-diyl) ester
- CBNumber:
- CB72456370
- Molecular Formula:
- C34H26O8
- Molecular Weight:
- 562.57
- MDL Number:
- MFCD11113135
- MOL File:
- 858134-23-3.mol
TERRESTRIN A price More Price(11)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 10010519 | Vialinin A ≥98% | 858134-23-3 | 1mg | $91 | 2024-03-01 | Buy |
| Cayman Chemical | 10010519 | Vialinin A ≥98% | 858134-23-3 | 5mg | $295 | 2024-03-01 | Buy |
| Cayman Chemical | 10010519 | Vialinin A ≥98% | 858134-23-3 | 10mg | $385 | 2021-12-16 | Buy |
| Cayman Chemical | 10010519 | Vialinin A ≥98% | 858134-23-3 | 25mg | $805 | 2021-12-16 | Buy |
| Usbiological | 257045 | Vialinin A | 858134-23-3 | 1mg | $319 | 2021-12-16 | Buy |
TERRESTRIN A Chemical Properties,Uses,Production
Uses
Vialinin A is a Potent Inhibitor of TNF-α production. Vialinin A is a potent antioxidant.
Biological Activity
vialinin a is a potent inhibitor of ubiquitin-specific peptidases with ic50 values of 1.5, 5.9 and 22.3 μm for ubiquitin-specific peptidase 4 (usp4), usp5/isopeptidase t (isot) and uch-l1 deubiquitinating enzyme (dub), respectively [1].ubiquitin-specific peptidases (usps) are a series of proteases that deubiquitinate target proteins. the dynamic modification of a protein with ubiquitin can modify its function, localization and fate in the cell. ubiquitin hydrolase plays an important role in immunology and infection [2].in rbl-2h3 cells, vialinin a inhibited tnf-ɑ production and release and inhibited usp5 enzymatic activity. in usp5 sirna-knockdown rbl-2h3 cells, vialinin a inhibited tnf-ɑ production and release in a dose dependent way. also, the mrna expression of tnf-ɑ was decreased significantly [2]. in rbl-2h3 cells, vialinin a inhibited tnf-ɑ production with ic50 value of 0.09 nm. also, it inhibited the release of interleukin 4, β-hexosaminidase and monocyte chemotactic protein 1, which suggested vialinin a had anti-allergic activities [3].
References
[1]. okada k, ye yq, taniguchi k, et al. vialinin a is a ubiquitin-specific peptidase inhibitor. bioorg med chem lett, 2013, 23(15): 4328-4331.
[2]. yoshioka y, ye yq, okada k, et al. ubiquitin-specific peptidase 5, a target molecule of vialinin a, is a key molecule of tnf-α production in rbl-2h3 cells. plos one, 2013, 8(12): e80931.
[3]. onose j, xie c, ye yq, et al. vialinin a, a novel potent inhibitor of tnf-alpha production from rbl-2h3 cells. biol pharm bull, 2008, 31(5): 831-833.
TERRESTRIN A Preparation Products And Raw materials
Raw materials
Preparation Products
TERRESTRIN A Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Shanghai Aladdin Bio-Chem Technology Co.,LTD | 18521735133 18521732826; | market@aladdin-e.com | China | 25015 | 65 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7892 | 56 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| MedBioPharmaceutical Technology Inc | 021-69568360 18916172912 | order@med-bio.cn | China | 8141 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
| Shanghai Yifei Biotechnology Co. , Ltd. | 021-65675885 18964387627 | customer_service@efebio.com | China | 8740 | 58 |