ChemicalBook >> CAS DataBase List >>AT-56
AT-56
- CAS No.
- 162640-98-4
- Chemical Name:
- AT-56
- Synonyms
- AT 56;CS-1414;AT56/AT-56;AT 56, >=98%;AT-56 AT-7519;4-Dibenzo[a,d]cyclohepten-5-ylidene-1-[4-(2H-tetrazol-5-yl)-butyl]-piperidine;4-Dibenzo[a,d] cyclohepten-5-ylidene-1-[4-(1H-tetrazol-5-yl) butyl] piperdine;4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(1H-tetrazol-5-yl)butyl]piperidine;4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine;Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-
- CBNumber:
- CB72518821
- Molecular Formula:
- C25H27N5
- Molecular Weight:
- 397.52
- MDL Number:
- MFCD18086874
- MOL File:
- 162640-98-4.mol
- MSDS File:
- SDS
Last updated:2023-12-04 14:30:45
| Boiling point | 620.4±65.0 °C(Predicted) |
|---|---|
| Density | 1.216±0.06 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | DMSO: soluble10mg/mL, clear |
| pka | 4.99±0.10(Predicted) |
| form | powder |
| color | white to beige |
| InChIKey | LQNGMDUIRLSESZ-UHFFFAOYSA-N |
| SMILES | N1(CCCCC2=NNN=N2)CC/C(=C2/C3=CC=CC=C3C=CC3=CC=CC=C3/2)/CC1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS02,GHS07 |
|---|---|
| Signal word | Danger |
| Hazard statements | H315-H319-H228 |
| Precautionary statements | P240-P210-P241-P264-P280-P302+P352-P370+P378-P337+P313-P305+P351+P338-P362+P364-P332+P313 |
| WGK Germany | 3 |
AT-56 price More Price(29)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0856 | AT-56 ≥98% (HPLC) | 162640-98-4 | 5mg | $107 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0856 | AT-56 ≥98% (HPLC) | 162640-98-4 | 25mg | $419 | 2024-03-01 | Buy |
| Cayman Chemical | 13160 | AT-56 ≥95% | 162640-98-4 | 1mg | $37 | 2024-03-01 | Buy |
| Cayman Chemical | 13160 | AT-56 ≥95% | 162640-98-4 | 5mg | $90 | 2024-03-01 | Buy |
| Cayman Chemical | 13160 | AT-56 ≥95% | 162640-98-4 | 10mg | $161 | 2024-03-01 | Buy |
AT-56 Chemical Properties,Uses,Production
Uses
AT-56 is an orally active inhibitor of Lipocalin-type prostaglandin D synthase.
in vitro
AT-56 (1-30 μM; 10 minutes) dose-dependently inhibits the production of PGD2 in L-PGDS-expressing human medulloblastoma TE-671 cells with an IC50 of about 3 μM.
in vivo
AT-56 (1-30 mg/kg; p.o.) suppresses the PGD2 production in the stab-wounded brain.
AT-56 (1-10 mg/kg; p.o.) suppresses the L-PGDS-mediated allergic airway inflammation in mice.
AT-56 (10 mg/kg; p.o.) exhibits Cmax (2.15 μg/ml), half-life (1.71 h) and high oral bioavailability (82%).
storage
Store at -20°C
AT-56 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 92)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
View Lastest Price from AT-56 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
![4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine pictures](https://img.chemicalbook.com/ProductImageEN/2019-9/Small/d330a174-c4e0-491b-b584-ffde058fc907.png) |
2019-09-04 | 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine
162640-98-4
|
US $5.00 / KG | 1KG | 99% | 1ton | Career Henan Chemical Co |
-
- 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine
162640-98-4
- US $5.00 / KG
- 99%
- Career Henan Chemical Co
AT56/AT-56
4-(DIBENZO[1,2-A:1',2'-E][7]ANNULEN-11-YLIDENE)-1-[4-(2H-TETRAZOL-5-YL)BUTYL]PIPERIDINE
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(1H-tetrazol-5-yl)butyl]piperidine
4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine
AT 56
4-Dibenzo[a,d]cyclohepten-5-ylidene-1-[4-(2H-tetrazol-5-yl)-butyl]-piperidine
AT 56, >=98%
CS-1414
Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-
4-Dibenzo[a,d] cyclohepten-5-ylidene-1-[4-(1H-tetrazol-5-yl) butyl] piperdine
AT-56
AT-7519
Lipocalin-type,L-PGDS,synthase,prostaglandin,Inhibitor,AT56,PGE synthase,inflammatory,AT 56,Prostaglandin E synthase,drowsiness,inhibit,AT-56
162640-98-4
C25H27N5
Inhibitors