ChemicalBook >> CAS DataBase List >>2,4-DIFLUOROPYRIMIDINE

2,4-DIFLUOROPYRIMIDINE

CAS No.
2802-61-1
Chemical Name:
2,4-DIFLUOROPYRIMIDINE
Synonyms
EOS-61621;NSC 331813;2,4-DIFLUOROPYRIMIDINE;2,4-DIFLUOROPYRIMMIDINE;Pyrimidine, 2,4-difluoro-;2,4-Difluoropyrimidine98%;2,4-Difluoropyrimidine 98%;Pyrimidine, 2,4-difluoro- (6CI,8CI,9CI);2,4-DIFLUOROPYRIMIDINE ISO 9001:2015 REACH
CBNumber:
CB7263268
Molecular Formula:
C4H2F2N2
Molecular Weight:
116.07
MDL Number:
MFCD04972830
MOL File:
2802-61-1.mol
MSDS File:
SDS
Last updated:2023-04-23 13:52:06

2,4-DIFLUOROPYRIMIDINE Properties

Boiling point 118-120 °C
Density 1.359 g/mL at 25 °C
refractive index n20/D 1.432
Flash point 106 °F
pka -2.52±0.20(Predicted)
form liquid
color Clear, colourless
CAS DataBase Reference 2802-61-1(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H226-H302-H315-H318-H335
Precautionary statements  P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  10-22-37/38-41
Safety Statements  26-39
RIDADR  UN 1993 3/PG 3
WGK Germany  3
Hazard Note  Irritant
HazardClass  3
PackingGroup  III
HS Code  29335990

2,4-DIFLUOROPYRIMIDINE price More Price(23)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 661082 2,4-Difluoropyrimidine 97% 2802-61-1 500mg $161 2023-06-20 Buy
Sigma-Aldrich 661082 2,4-Difluoropyrimidine 97% 2802-61-1 100mg $53.6 2023-01-07 Buy
TRC D448643 2,4-Difluoropyrimidine 2802-61-1 100mg $60 2021-12-16 Buy
Apolloscientific PC1056 2,4-Difluoropyrimidine 98% 2802-61-1 1g $67 2021-12-16 Buy
SynQuest Laboratories 3H32-3-X9 2,4-Difluoropyrimidine 98% 2802-61-1 1g $108 2021-12-16 Buy
Product number Packaging Price Buy
661082 500mg $161 Buy
661082 100mg $53.6 Buy
D448643 100mg $60 Buy
PC1056 1g $67 Buy
3H32-3-X9 1g $108 Buy

2,4-DIFLUOROPYRIMIDINE Chemical Properties,Uses,Production

Synthesis

Crown ethers are able to enhance the performance of KF in two ways. Firstly, they complex the potassium cation making a better fluoride source and secondly they increase the solubility of KF in the solvent. KF with a catalytic amount of dicyclohexano-18-crown-6 in tetraglyme converted 2,4-dichloropyrimidine into 2,4-difluoropyrimidine.

Uses

2,4-Difluoropyrimidine can be used as a starting material to synthesize:

  • 3-Pyrimidin-4-yl-oxazolidin-2-one derivatives as mutant isocitrate dehydrogenase (IDH1) inhibitors.
  • N,N′-(1,4-phenylenebis(methylene))bis(2-fluoropyrimidin-4-amine) as chemokine receptor type 4 antagonists.

Synthesis Reference(s)

Journal of Heterocyclic Chemistry, 22, p. 149, 1985 DOI: 10.1002/jhet.5570220137

3934-20-1
2802-61-1
Synthesis of 2,4-DIFLUOROPYRIMIDINE from 2,4-Dichloropyrimidine

2,4-DIFLUOROPYRIMIDINE Preparation Products And Raw materials

Global( 81)Suppliers
Supplier Tel Email Country ProdList Advantage
Changzhou Ansciep Chemical Co., Ltd.
+86 519 86305871 sales@ansciepchem.com CHINA 4242 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63711 58
Wuhan Chemwish Technology Co., Ltd
027-67849912 sales@chemwish.com CHINA 10828 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Antai Fine Chemical Technology Co.,Limited
18503026267 info@antaichem.com CHINA 9641 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-89586680 +86-18192503167 1026@dideu.com China 9126 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 28404 58
Coresyn Pharmatech Co., Ltd.
+86-571-86626709 +86-18157142896 cbc@coresyn.com China 9991 58

View Lastest Price from 2,4-DIFLUOROPYRIMIDINE manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,4-DIFLUOROPYRIMIDINE pictures 2024-04-17 2,4-DIFLUOROPYRIMIDINE
2802-61-1
US $1.10 / g 1g 99.0% min 100 tons min Shaanxi Dideu Medichem Co. Ltd
2,4-DIFLUOROPYRIMIDINE  pictures 2021-12-04 2,4-DIFLUOROPYRIMIDINE
2802-61-1
US $1.10 / g 1g 99.00% 100 Tons Min Dideu Industries Group Limited
2,4-DIFLUOROPYRIMIDINE pictures 2020-01-10 2,4-DIFLUOROPYRIMIDINE
2802-61-1
US $9.80 / KG 1KG ≥98% 20 tons Career Henan Chemical Co
2,4-DIFLUOROPYRIMIDINE NSC 331813 Pyrimidine, 2,4-difluoro- (6CI,8CI,9CI) 2,4-Difluoropyrimidine 98% 2,4-Difluoropyrimidine98% EOS-61621 Pyrimidine, 2,4-difluoro- 2,4-DIFLUOROPYRIMIDINE ISO 9001:2015 REACH 2,4-DIFLUOROPYRIMMIDINE 2802-61-1 Pyrimidines Heterocyclic Building Blocks Building Blocks PYRIMIDINE Halides Pyrazines, Pyrimidines & Pyridazines Heterocyclic Compounds Pyrazines, Pyrimidines & Pyridazines Building Blocks Heterocyclic Building Blocks Pyrimidines