ChemicalBook >> CAS DataBase List >>Mobocertinib
Mobocertinib
- CAS No.
- 1847461-43-1
- Chemical Name:
- Mobocertinib
- Synonyms
- Mobocertinib;Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate;Mobocertinib (TAK788);5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-[(1-oxo-2-propen-1-yl)amino]phenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester;TAK-788;TAK788 TAK-788;ak-788 Mobotinib;2H6]-Mobocertinib;AP32788, MOBOCERTINIB;TAK-788 (MOBOCERTINIB)
- CBNumber:
- CB74676602
- Molecular Formula:
- C32H39N7O4
- Molecular Weight:
- 585.71
- MDL Number:
- MFCD32669806
- MOL File:
- 1847461-43-1.mol
Last updated:2024-01-25 16:30:26
storage temp. | Store at -20°C |
---|---|
solubility | DMF: 10 mg/ml,DMF:PBS (pH 7.2) (1:8): 0.11 mg/ml |
form | A crystalline solid |
FDA UNII | 39HBQ4A67L |
NCI Drug Dictionary | mobocertinib |
Mobocertinib price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
ChemScene | CS-0114256 | Mobocertinib 98.92% | 1847461-43-1 | 10mg | $60 | 2021-12-16 | Buy |
ChemScene | CS-0114256 | Mobocertinib 98.92% | 1847461-43-1 | 100mg | $250 | 2021-12-16 | Buy |
ChemScene | CS-0114256 | Mobocertinib 98.92% | 1847461-43-1 | 500mg | $950 | 2021-12-16 | Buy |
DC Chemicals | 013004 | Mobocertinib(TAK-788) | 1847461-43-1 | 003 | $1800 | 2021-12-16 | Buy |
DC Chemicals | 013004 | Mobocertinib(TAK-788) | 1847461-43-1 | 001 | $450 | 2021-12-16 | Buy |
Mobocertinib Chemical Properties,Uses,Production
Uses
Mobocertinib (TAK-788) is an orally active and irreversible EGFR/HER2 inhibitor. Mobocertinib effectively inhibits oncogenic variants containing mutations that activate the EGFRex20ins, with selectivity superior to that of wild-type EGFR. Mobocertinib is FDA-approved for the treatment of patients with non-small cell lung cancer (NSCLC) who have a HER2 mutation or an EGFR mutation, including an exon 20 insertion mutation. Mobocertinib is approved by the FDA for the treatment of patients with non-small cell lung cancer (NSCLC) who have HER2 mutations or EGFR mutations, including exon 20 insertion mutations.
Mobocertinib Preparation Products And Raw materials
Raw materials
Preparation Products
Mobocertinib Suppliers
Global( 126)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
JIAXING REGEN CHEMICAL CO.,LTD | +8613385739570 | regen_chemical1@163.com | China | 226 | 58 |
Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 6710 | 58 |
ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
Related articles
- Mobocertinib: Synthesis and Introduction
- Mobocertinib was approved as the first treatment for NSCLC with epidermal growth factor receptor (EGFR) exon 20 insertion muta....
- Jan 25,2024
View Lastest Price from Mobocertinib manufacturers
TAK-788
AP32788, MOBOCERTINIB
Mobocertinib (TAK788, AP32788)
Mobocertinib
Mobocertinib (TAK788)
Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate
5-Pyrimidinecarboxylic acid, 2-[[4-[[2-(dimethylamino)ethyl]methylamino]-2-methoxy-5-[(1-oxo-2-propen-1-yl)amino]phenyl]amino]-4-(1-methyl-1H-indol-3-yl)-, 1-methylethyl ester
propan-2-yl 2-[4-[2-(dimethylamino)ethyl-methylamino]-2-methoxy-5-(prop-2-enoylamino)anilino]-4-(1-methylindol-3-yl)pyrimidine-5-carboxylate
2H6]-Mobocertinib
TAK-788 (MOBOCERTINIB)
TAK788 TAK-788
ak-788 Mobotinib
1847461-43-1
C32H39N7O4
API