DIHYDROERGOTAMINE
- CAS No.
- 511-12-6
- Chemical Name:
- DIHYDROERGOTAMINE
- Synonyms
- Levadex;DIHYDROERGOTAMINE;Dihydro Ergotamine D5;9,10-Dihydroergotamine;DIHYDROERGOTAMINE USP/EP/BP;Dihydro Ergotamine Impurity 4;Dihydroergotamine (base and/or unspecified salts);9,10α-Dihydro-12'-hydroxy-2'-methyl-5'α-(phenylmethyl)ergotaman-3',6',18-trione;Ergotaman-3',6',18-trione, 9,10-dihydro-12'-hydroxy-2'-methyl-5'-(phenylmethyl)-, (5'α,10α)-;Ergotaman-3′,6′,18-trione, 9,10-dihydro-12′-hydroxy-2′-methyl-5′-(phenylmethyl)-, (5′α,10α)-
- CBNumber:
- CB7482038
- Molecular Formula:
- C33H37N5O5
- Molecular Weight:
- 583.68
- MDL Number:
- MFCD00215847
- MOL File:
- 511-12-6.mol
| Product description | Number | Pack Size | Price |
| Dihydroergotamine 98% | API-1428 | 5g | $660 |
| Melting point | 239° |
|---|---|
| alpha | D20 -64°; 20546 -79° (c = 0.5 in pyridine) |
| Boiling point | 641.14°C (rough estimate) |
| Density | 1.1992 (rough estimate) |
| refractive index | 1.7500 (estimate) |
| pka | 9≅+-.0.60(Predicted) |
| EWG's Food Scores | 1 |
| FDA UNII | 436O5HM03C |
| ATC code | N02CA01,N02CA51 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P264-P270-P301+P312-P330-P501 |
DIHYDROERGOTAMINE Chemical Properties,Uses,Production
Uses
Anti-adrenergic.
Uses
Levadex is an intermediate in the synthesis of 2’-Epidihydroergotamine (E584910), which is an ergot alkaloid that exhibits potential neuroprotective properties against degenerative diseases.
Definition
ChEBI: Ergotamine in which a single bond replaces the double bond between positions 9 and 10. A semisynthetic ergot alkaloid with weaker oxytocic and vasoconstrictor properties than ergotamine, it is used (as the methanesulfonic or tartaric acid salts) for the tr atment of migraine and orthostatic hypotension.
brand name
D.H.E. 45 (Valeant); Migranal (Valeant) .
