5-Bromo-1-methyl-1H-indole
- CAS No.
- 10075-52-2
- Chemical Name:
- 5-Bromo-1-methyl-1H-indole
- Synonyms
- CHEMBRDG-BB 9072049;N-Methyl-5-bromoindole;1-methyl-5-bromoindole;5-BROMO-1-METHYL-INDOLE;5-Bromo-1-methy-1H-indole;5-BROMO-1-METHYL-1H-INDOLE;5-Bromo-1-methylindole 97%;1H-Indole,5-bromo-1-methyl-;5-
Bromo- 1- methylindole;5-bromo-1-methyl-1H-indole(SALTDATA: FREE)
- CBNumber:
- CB7783698
- Molecular Formula:
- C9H8BrN
- Molecular Weight:
- 210.07
- MDL Number:
- MFCD00159857
- MOL File:
- 10075-52-2.mol
- MSDS File:
- SDS
| Product description | Number | Pack Size | Price |
| 5-Bromo-1-methylindole 97% | 718300 | 5g | $200 |
| 5-Bromo-1-methyl-1H-indole min. 98.0 % | B5263 | 1G | $40 |
| 5-Bromo-1-methyl-1H-indole min. 98.0 % | B5263 | 5G | $119 |
| 5-Bromo-1-methyl-1H-indole | B697293 | 100mg | $45 |
| 5-Bromo-1-methyl-1H-indole | B697293 | 250mg | $55 |
| More product size | |||
| Melting point | 43 °C |
|---|---|
| Boiling point | 300.9±15.0 °C(Predicted) |
| Density | 1.47±0.1 g/cm3(Predicted) |
| Flash point | >110℃ |
| storage temp. | Sealed in dry,Room Temperature |
| form | solid |
| Appearance | Light yellow to yellow Solid |
| InChI | InChI=1S/C9H8BrN/c1-11-5-4-7-6-8(10)2-3-9(7)11/h2-6H,1H3 |
| InChIKey | SBOITLSQLQGSLO-UHFFFAOYSA-N |
| SMILES | N1(C)C2=C(C=C(Br)C=C2)C=C1 |
| UNSPSC Code | 12352100 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS05,GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H315-H318-H335 | |||||||||
| Precautionary statements | P280-P301+P312+P330-P302+P352-P305+P351+P338+P310 | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 22-36/37/38-41-37/38 | |||||||||
| Safety Statements | 22-26-36/37/39-39 | |||||||||
| WGK Germany | 3 | |||||||||
| Hazard Note | Irritant | |||||||||
| HS Code | 2933998090 | |||||||||
| NFPA 704 |
|
5-Bromo-1-methyl-1H-indole price More Price(39)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 718300 | 5-Bromo-1-methylindole 97% | 10075-52-2 | 5g | $200 | 2023-06-20 | Buy |
| TCI Chemical | B5263 | 5-Bromo-1-methyl-1H-indole min. 98.0 % | 10075-52-2 | 1G | $40 | 2025-07-31 | Buy |
| TCI Chemical | B5263 | 5-Bromo-1-methyl-1H-indole min. 98.0 % | 10075-52-2 | 5G | $119 | 2025-07-31 | Buy |
| TRC | B697293 | 5-Bromo-1-methyl-1H-indole | 10075-52-2 | 100mg | $45 | 2021-12-16 | Buy |
| TRC | B697293 | 5-Bromo-1-methyl-1H-indole | 10075-52-2 | 250mg | $55 | 2021-12-16 | Buy |
5-Bromo-1-methyl-1H-indole Chemical Properties,Uses,Production
Synthesis
10075-50-0
74-88-4
10075-52-2
1. 5-bromo-1H-indole (2.08 g, 10.6 mmol) was dissolved in 35 mL of DMF at 0 °C. 2. Sodium hydride (60% dispersed in mineral oil, 467 mg, 11.67 mmol) was added to the above solution, keeping the reaction temperature at 0 °C. 3. After stirring for 30 min, iodomethane (663 μL, 10.6 mmol) was slowly added. 4. The reaction mixture was gradually warmed to room temperature and stirring was continued for 10 min. 5. Upon completion of the reaction, the reaction was quenched with ice water at 0 °C. The reaction was then quenched with ice water. 6. The reaction mixture was extracted with ethyl acetate (3 × appropriate amount). 7. 7. The organic phases were combined, dried over anhydrous magnesium sulfate, filtered and concentrated. 8. The product was purified by fast column chromatography (eluent: 10% ethyl acetate/hexane) to give 5-bromo-1-methyl-1H-indole (2.16 g, 97% yield). 9. The product was analyzed by 1H NMR. 9. The product was characterized by 1H NMR (400 MHz, CDCl3): δ 7.74 (d, J = 1.6 Hz, 1H), 7.30 (dd, J = 8.4, 2.0 Hz, 1H), 7.19 (d, J = 8.8 Hz, 1H), 7.05 (d, J = 3.2 Hz, 1H), 6.42 (d, J = 2.8 Hz, 1H), 3.78 (s, 3H), 6.42 (d, J = 2.8 Hz, 1H) 3.78 (s, 3H).
References
[1] Chemistry Letters, 1991, # 7, p. 1125 - 1128
[2] Bioorganic and Medicinal Chemistry Letters, 1999, vol. 9, # 3, p. 333 - 336
[3] Organic Letters, 2015, vol. 17, # 2, p. 254 - 257
[4] Patent: WO2016/114816, 2016, A1. Location in patent: Paragraph 0332
[5] Bioorganic and Medicinal Chemistry, 2010, vol. 18, # 12, p. 4524 - 4529
5-Bromo-1-methyl-1H-indole Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29850 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 21193 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Wuhan Chemwish Technology Co., Ltd | 027-67849912 | sales@chemwish.com | CHINA | 10821 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49975 | 58 |
| SIMAGCHEM CORP | +86-5922680277 +86-13806087780 | sale@simagchem.com | China | 17346 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | +86-0571-88938639 +8617705817739 | info@dycnchem.com | China | 52846 | 58 |
| Henan Alfa Chemical Co., Ltd | +8615838112936 | alfa10@alfachem.cn | China | 12921 | 58 |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12373 | 58 |
View Lastest Price from 5-Bromo-1-methyl-1H-indole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-07-06 | 5-Bromo-1-methyl-1H-indole
10075-52-2
|
US $0.00 / KG | 1KG | 98% | 150KG | Career Henan Chemical Co |
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- 5-Bromo-1-methyl-1H-indole
10075-52-2
- US $0.00 / KG
- 98%
- Career Henan Chemical Co
