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Protocatechualdehyde

Description
Protocatechualdehyde
Protocatechualdehyde structure
CAS No.
139-85-5
Chemical Name:
Protocatechualdehyde
Synonyms
Nc 033;NSC 22961;AURORA 17180;PROTOPINE(RG);rancinamyciniv;Rancinamycin IV;4-Formylcatechol;AKOS BBS-00003254;Protocatecualdehyde;pyrocatechualdehyde
CBNumber:
CB7784165
Molecular Formula:
C7H6O3
Formula Weight:
138.12
MOL File:
139-85-5.mol

Protocatechualdehyde Properties

Melting point:
150-157 °C(lit.)
Boiling point:
213.5°C (rough estimate)
Density 
1.2667 (rough estimate)
refractive index 
1.4600 (estimate)
storage temp. 
2-8°C
solubility 
6.3g/l
form 
Crystalline Powder
pka
pK (25°) 7.55
color 
slightly brown
Water Solubility 
50 g/L (20 ºC)
Sensitive 
Air Sensitive
Merck 
14,7893
BRN 
774381
Stability:
Stable. Incompatible with strong bases, strong oxidizing agents.
CAS DataBase Reference
139-85-5(CAS DataBase Reference)
NIST Chemistry Reference
3,4-Dihydroxybenzaldehyde(139-85-5)
EPA Substance Registry System
Benzaldehyde, 3,4-dihydroxy-(139-85-5)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xi
Risk Statements  36/37/38-22
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  UL0380000
9
Hazard Note  Irritant/Air Sensitive
HS Code  29124900
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

Protocatechualdehyde price More Price(13)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 37520 3,4-Dihydroxybenzaldehyde purum, ≥97.0% (HPLC) 139-85-5 25g $111 2018-11-13 Buy
Sigma-Aldrich 37520 3,4-Dihydroxybenzaldehyde purum, ≥97.0% (HPLC) 139-85-5 100g $262 2018-11-13 Buy
TCI Chemical D0566 3,4-Dihydroxybenzaldehyde >98.0%(GC)(T) 139-85-5 25g $18 2018-11-22 Buy
TCI Chemical D0566 3,4-Dihydroxybenzaldehyde >98.0%(GC)(T) 139-85-5 250g $120 2018-11-22 Buy
Alfa Aesar A11558 3,4-Dihydroxybenzaldehyde, 98% 139-85-5 5g $40.5 2018-11-13 Buy

Protocatechualdehyde Chemical Properties,Uses,Production

Description

Is a phenolic aldehyde crystalline compound with the molecular formula C7H6O3. The compound is released from cork stoppers into wine. Also known as procatechuic aldehyde, protocatechualdehyde can be found in barley, grapevine, green Cavendish, and root of herb S. miltiorrhiza. The compound contains pro-apoptotic and antiproliferative properties against human breast cancer cells as well as colorectal cancer cells by reducing the expression of cyclin D1 and β-catenin.

Chemical Properties

brown powder

Enzyme inhibitor

This aldehyde (FW = 138.12 g/mol), also known as 3,4- dihydroxybenzaldehyde and 4-formylcatechol, is soluble in water (5 g/100 mL at 20°C) and has a pKa value of 7.55 at 25°C. Protocatechualdehyde induces apoptosis in cytotoxic T cells. Target(s): aldehyde oxidase; aldose reductase; b-carotene 15,15’-monooxygenase; mandelonitrile lyase; protocatechuate 3,4-dioxygenase; protocatechuate 4,5- dioxygenase; tyrosinase, weakly inhibited, IC50 = 620 μM; and xanthine oxidase.

Purification Methods

Crystallise the aldehyde from water or toluene and dry it in a vacuum desiccator over KOH pellets or shredded wax respectively. [Beilstein 8 IV 1762.]

Protocatechualdehyde Preparation Products And Raw materials

Raw materials

Preparation Products


Protocatechualdehyde Suppliers

Global( 473)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
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0755-23311925 Abel@chembj.com CHINA 3202 55
Henan DaKen Chemical CO.,LTD.
+86-371-55531817
info@dakenchem.com CHINA 21915 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693
0371-55170693 info@tianfuchem.com CHINA 20675 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32451 55
Nanjing ChemLin Chemical Industry Co., Ltd.
025-83697070;product@chemlin.com.cn
product@chemlin.com.cn CHINA 3015 60
Hefei TNJ Chemical Industry Co.,Ltd.
86-0551-65418684 18949823763
86-0551-65418684 info@tnjchem.com China 1821 55
Chongqing Chemdad Co.,Ltd
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Xiamen AmoyChem Co., Ltd
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Shanghai Zheyan Biotech Co., Ltd.
18017610038
zheyansh@163.com CHINA 3623 58
career henan chemical co
+86-371-86658258
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View Lastest Price from Protocatechualdehyde manufacturers

Image Release date Product Price Min. Order Purity Supply Ability Manufacturer
2019-07-17 3,4-Dihydroxybenzaldehyde 139-85-5
139-85-5
US $30.00 / g 1g ≥98% 1000.00 kgs NanJing Spring & Autumn Biological Engineering CO., LTD.
2019-07-17 3,4-Dihydroxybenzaldehyde 139-85-5
139-85-5
US $30.00 / g 1g ≥98% 1000.00 kgs NanJing Spring & Autumn Biological Engineering CO., LTD.
2018-08-16 Protocatechualdehyde
139-85-5
US $1.00 / KG 1KG 98% 500kg career henan chemical co

Protocatechualdehyde Spectrum


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