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Pomalidomide-PEG4-azide

Pomalidomide-PEG4-azide Structure
Pomalidomide-PEG4-azide structure
CAS No.
2271036-47-4
Chemical Name:
Pomalidomide-PEG4-azide
Synonyms
Pomalidomide-PEG?-Azide;Pomalidomide-PEG4-azide;Pomalidomide-NH-?PEG4-?azide;4-((14-azido-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;14-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-3,6,9,12-tetraoxatetradecanamide, Crosslinker-E3 ligase ligand conjugate, Pomalidomide conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber:
CB78054794
Molecular Formula:
C23H30N6O8
Molecular Weight:
518.53
MDL Number:
MFCD32693349
MOL File:
2271036-47-4.mol
Last updated:2024-04-01 13:48:23
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Pomalidomide-PEG4-azide Properties

storage temp. 2-8°C

Pomalidomide-PEG4-azide Chemical Properties,Uses,Production

Uses

Protein degrader builiding block Pomalidomide-PEG4-Azide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand and a PEGylated crosslinker with pendant azide for click chemistry with a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant azide, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

storage

Store at -20°C

Pomalidomide-PEG4-azide Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide-PEG4-azide Suppliers

Global( 25)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Jilin Chinese Academy of Sciences-yanshen Technology 		+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2893 58
Aladdin Scientific 		+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 400-6206333 18521732826; market@aladdin-e.com China 25015 65
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Shanghai Chaolan Chemical Technology Center QQ:65489617 15618227136 info@SuperLan-chem.com China 9440 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4955 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1285 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Jilin Chinese Academy of Sciences-yanshen Technology 		58
Xian confluore Biological Technology Co., Ltd. 		58
Aladdin Scientific 		58
Shanghai Aladdin Bio-Chem Technology Co.,LTD 65
Sigma-Aldrich 80
Shanghai Chaolan Chemical Technology Center 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Xi'an Confluore Biological Technology Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58

View Lastest Price from Pomalidomide-PEG4-azide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-NH-PEG4-azide pictures 2024-04-02 Pomalidomide-NH-PEG4-azide
2271036-47-4
 US $0.00 / mg 100mg >95.00% 100mg Xian confluore Biological Technology Co., Ltd.

2271036-47-4(Pomalidomide-PEG4-azide)Related Search:

Pomalidomide-PEG2-N3 Pomalidomide-PEG2-butyl iodide E3 Ligase Ligand-Linker Conjugates 22 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide-PEG4-CO2H
E3 Ligase Ligand-Linker Conjugates 1 POMALIDOMIDE-PEG2-CO2H Pomalidomide-PEG1-azide Pomalidomide-PEG5-CO2H POMALIDOMIDE-PEG1-CO2H
Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]- Pomalidomide-PEG3-N3 Pomalidomide-PEG6-butyl iodide Pomalidomide-NH-PEG2-azide
Pomalidomide-NH-PEG6-azide Pomalidomide-NH-PEG1-azide Pomalidomide-NH-PEG5-azide

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Pomalidomide-PEG4-azide Pomalidomide-NH-?PEG4-?azide 4-((14-azido-3,6,9,12-tetraoxatetradecyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione 14-Azido-N-(2-(2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-3,6,9,12-tetraoxatetradecanamide, Crosslinker-E3 ligase ligand conjugate, Pomalidomide conjugate, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader Pomalidomide-PEG?-Azide 2271036-47-4