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Pomalidomide-PEG6-butyl iodide

Pomalidomide-PEG6-butyl iodide Structure
Pomalidomide-PEG6-butyl iodide structure
CAS No.
1835705-74-2
Chemical Name:
Pomalidomide-PEG6-butyl iodide
Synonyms
Pomalidomide-2-2-2-2-2-2-6-I;Pomalidomide-PEG6-butyl iodide;Pomalidomide-PEG?-butyl iodide;Pomalidomide-PEG6-butyl iodide;N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-24-iodo-3,6,9,12,15,18-hexaoxatetracosanamide;Acetamide, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-2-[(21-iodo-3,6,9,12,15-pentaoxaheneicos-1-yl)oxy]-;N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-24-iodo-3,6,9,12,15,18-hexaoxatetracosanamide, Crosslinker?E3 Ligase ligand conjugate, Pomalidomide-2-2-2-2-2-2-6-I, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader
CBNumber:
CB04919986
Molecular Formula:
C31H44IN3O11
Molecular Weight:
761.6
MDL Number:
MFCD32173803
MOL File:
1835705-74-2.mol
MSDS File:
SDS
Last updated:2025-07-23 21:37:54
Product description Number Pack Size Price
Pomalidomide-PEG6-butyl iodide ≥95% 903442 50MG $521
Pomalidomid-PEG6-butyl-I PTC1720 50mg $634.5
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Pomalidomide-PEG6-butyl iodide Properties

Boiling point 853.5±65.0 °C(Predicted)
Density 1.448±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO : 100 mg/mL (131.30 mM; Need ultrasonic)
pka 10.68±0.40(Predicted)
form Solid
color White to off-white
UNSPSC Code 12352101
NACRES NA.22

Pomalidomide-PEG6-butyl iodide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 903442 Pomalidomide-PEG6-butyl iodide ≥95% 1835705-74-2 50MG $521 2025-07-31 Buy
Iris Biotech GmbH PTC1720 Pomalidomid-PEG6-butyl-I 1835705-74-2 50mg $634.5 2021-12-16 Buy
Product number Packaging Price Buy
903442 50MG $521 Buy
PTC1720 50mg $634.5 Buy

Pomalidomide-PEG6-butyl iodide Chemical Properties,Uses,Production

Uses

Protein degrader builiding block Pomalidomide-PEG6-butyl iodide enables the synthesis of molecules for targeted protein degradation and PROTAC (proteolysis-targeting chimeras) technology. This conjugate contains a Cereblon (CRBN)-recruiting ligand, a linker with both hydrophobic and hydrophilic moieties, and a pendant iodoalkane for reactivity with a nucleophilic group on a target ligand. Because even slight alterations in ligands and crosslinkers can affect ternary complex formation between the target, E3 ligase, and PROTAC, many analogs are prepared to screen for optimal target degradation. When used with other protein degrader building blocks with a pendant iodo group, parallel synthesis can be used to more quickly generate PROTAC libraries that feature variation in crosslinker length, composition, and E3 ligase ligand.

reaction suitability

reactivity: sulfuryl reactive
reagent type: ligand-linker conjugate

IC 50

Cereblon

Pomalidomide-PEG6-butyl iodide Preparation Products And Raw materials

Raw materials

Preparation Products

Pomalidomide-PEG6-butyl iodide Suppliers

Global( 21)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354; +17819995354 marketing@targetmol.com United States 32435 58
TargetMol Chemicals Inc. 		+1-781-999-5354; support@targetmol.com United States 39035 58
Xian confluore Biological Technology Co., Ltd. 		+86-15680926068 1924344760@confluore.cn China 2997 58
Aladdin Scientific 		tp@aladdinsci.com United States 52923 58
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51395 80
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9803 58
Xi'an Confluore Biological Technology Co., Ltd. +86-156-80926068 +86-15680926068 1924344760@qq.com China 4952 58
Jilin Province Woda Biotechnology Co., Ltd. 13504435624 1927928688@qq.com China 1615 58
Shaanxi borno biotechnology co., LTD +86-13759708231 asherw9@hotmail.com China 2373 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-8210725 4008210725 malulu@leyan.com China 55000 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
Xian confluore Biological Technology Co., Ltd. 		58
Aladdin Scientific 		58
Sigma-Aldrich 80
Shanghai EFE Biological Technology Co., Ltd. 58
Xi'an Confluore Biological Technology Co., Ltd. 58
Jilin Province Woda Biotechnology Co., Ltd. 58
Shaanxi borno biotechnology co., LTD 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58

View Lastest Price from Pomalidomide-PEG6-butyl iodide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Pomalidomide-PEG6-butyl iodide pictures 2025-07-22 Pomalidomide-PEG6-butyl iodide
1835705-74-2
 US $71.00 / mg 10g TargetMol Chemicals Inc.
Pomalidomide-2-2-2-2-2-2-6-I pictures 2025-06-07 Pomalidomide-2-2-2-2-2-2-6-I
1835705-74-2
 US $0.00 / mg 100mg >95.00% 100mg Xian confluore Biological Technology Co., Ltd.

1835705-74-2(Pomalidomide-PEG6-butyl iodide)Related Search:

E3 ligase Ligand-Linker Conjugates 50 Pomalidomide-PEG3-CO2H Pomalidomide-PEG2-N3 Pomalidomide-PEG4-azide Pomalidomide-PEG2-butyl iodide
E3 Ligase Ligand-Linker Conjugates 22 4-((2-(2-(2-(2-aminoethoxy)ethoxy)ethoxy)ethyl)amino)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione Pomalidomide-PEG4-CO2H E3 Ligase Ligand-Linker Conjugates 1 POMALIDOMIDE-PEG2-CO2H
Pomalidomide-PEG1-azide Pomalidomide-PEG5-CO2H POMALIDOMIDE-PEG1-CO2H Pomalidomide-O-C4-NH2 Propanoic acid, 3-[[17-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]amino]-3,6,9,12,15-pentaoxaheptadec-1-yl]oxy]-
Pomalidomide-PEG3-N3 Pomalidomide-PEG1-piperazine BI 3663

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Pomalidomide-PEG6-butyl iodide Pomalidomide-2-2-2-2-2-2-6-I Acetamide, N-[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1,3-dioxo-1H-isoindol-4-yl]-2-[(21-iodo-3,6,9,12,15-pentaoxaheneicos-1-yl)oxy]- N-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)-24-iodo-3,6,9,12,15,18-hexaoxatetracosanamide, Crosslinker?E3 Ligase ligand conjugate, Pomalidomide-2-2-2-2-2-2-6-I, Protein degrader building block for PROTAC? research, Template for synthesis of targeted protein degrader Pomalidomide-PEG?-butyl iodide N-[2-(2,6-dioxopiperidin-3-yl)-1,3-dioxo-2,3-dihydro-1H-isoindol-4-yl]-24-iodo-3,6,9,12,15,18-hexaoxatetracosanamide Pomalidomide-PEG6-butyl iodide 1835705-74-2