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ChemicalBook >> CAS DataBase List >>(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide

(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide

(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide Structure
(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide structure
CAS No.
149606-27-9
Chemical Name:
(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide
Synonyms
TZT 1027;Soblidotin;Auristatin PE;TZT-1027(Soblidotin);Soblidotin (Auristatin PE);TZT1027,inhibit,Microtubule/Tubulin,Inhibitor,TZT 1027,Soblidotin;L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[(2-phenylethyl)amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-;(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide
CBNumber:
CB81253823
Molecular Formula:
C39H67N5O6
Molecular Weight:
701.98
MDL Number:
MFCD09838692
MOL File:
149606-27-9.mol
MSDS File:
SDS
Last updated:2023-05-21 10:59:17
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(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide Properties

Melting point 73-79 °C
Boiling point 843.4±65.0 °C(Predicted)
Density 1.064±0.06 g/cm3(Predicted)
storage temp. Store at -20°C,unstable in solution, ready to use.
pka 13.95±0.46(Predicted)
Water Solubility Water : < 0.1 mg/mL (insoluble)
NCI Dictionary of Cancer Terms soblidotin; TZT-1027
FDA UNII DQC51A0WQH
NCI Drug Dictionary soblidotin

(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
ChemScene CS-6022 Soblidotin 99.64% 149606-27-9 1mg $168 2021-12-16 Buy
ChemScene CS-6022 Soblidotin 99.64% 149606-27-9 5mg $420 2021-12-16 Buy
American Custom Chemicals Corporation API0004192 SOBLIDOTIN 95.00% 149606-27-9 5MG $500.49 2021-12-16 Buy
ChemScene CS-6022 Soblidotin 99.64% 149606-27-9 10mg $600 2021-12-16 Buy
ChemScene CS-6022 Soblidotin 99.64% 149606-27-9 25mg $1200 2021-12-16 Buy
Product number Packaging Price Buy
CS-6022 1mg $168 Buy
CS-6022 5mg $420 Buy
API0004192 5MG $500.49 Buy
CS-6022 10mg $600 Buy
CS-6022 25mg $1200 Buy

(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide Chemical Properties,Uses,Production

Definition

ChEBI: Soblidotin is a tetrapeptide derivative of dolastatin 10. It is an inhibitor of tubulin polymerization which exhibits potent antitumor activity. It has a role as a microtubule-destabilising agent, an antineoplastic agent and an apoptosis inducer. It is functionally related to a 2-phenylethylamine and a L-valine.

(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide Preparation Products And Raw materials

Raw materials

Preparation Products

(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide Suppliers

Global( 38)Suppliers
Supplier Tel Email Country ProdList Advantage
Alpha Biopharmaceuticals Co., Ltd 		+86-411-39042497 +8613921981412 sales@alphabiopharm.com China 886 58
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
Zhejiang J&C Biological Technology Co.,Limited 		+1-2135480471 +1-2135480471 sales@sarms4muscle.com China 10523 58
ChemExpress 		+86-021-58950125 info@chemexpress.com China 555 58
Nextpeptide Inc 		+86-0571-81612335 +8613336028439 sales@nextpeptide.com China 19915 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Changzhou AniKare Pharmatech Co., Ltd. 		+86-0519-8359-8696 +8618018249389 sales@anikare.com China 8393 58
Shanghai Acmec Biochemical Technology Co., Ltd. 		+undefined18621343501 product@acmec-e.com China 33349 58
Shanghai Boyle Chemical Co., Ltd. 021-50182298 021-50180596 sales@boylechem.com China 2210 55
Supplier Advantage
Alpha Biopharmaceuticals Co., Ltd 		58
TargetMol Chemicals Inc. 		58
HANGZHOU CLAP TECHNOLOGY CO.,LTD 		58
Zhejiang J&C Biological Technology Co.,Limited 		58
ChemExpress 		58
Nextpeptide Inc 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
Changzhou AniKare Pharmatech Co., Ltd. 		58
Shanghai Acmec Biochemical Technology Co., Ltd. 		58
Shanghai Boyle Chemical Co., Ltd. 55

149606-27-9((2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide)Related Search:

(2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide 4,9-dioxo-5,10-diazatetradecane Butanamide, 3-methyl-N-(4-oxo-4-(propylamino)butyl)- 2-(4-Aminopentyl(ethyl)amino)ethanol dolastatin 10
TZT 1027 Soblidotin Auristatin PE TZT-1027(Soblidotin) (2S)-2-[[(2S)-2-dimethylamino-3-methyl-butanoyl]amino]-N-[(3R,4S,5S)-3 -methoxy-1-[(3R)-3-[(1R,2R)-1-methoxy-2-(phenethylcarbamoyl)propyl]pyr rolidin-1-yl]-5-methyl-1-oxo-heptan-4-yl]-N,3-dimethyl-butanamide L-Valinamide, N,N-dimethyl-L-valyl-N-[(1S,2R)-2-methoxy-4-[(2S)-2-[(1R,2R)-1-methoxy-2-methyl-3-oxo-3-[(2-phenylethyl)amino]propyl]-1-pyrrolidinyl]-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl- Soblidotin (Auristatin PE) TZT1027,inhibit,Microtubule/Tubulin,Inhibitor,TZT 1027,Soblidotin 149606-27-9 C39H67N5O6