ADRENORPHIN
- CAS No.
- 88377-68-8
- Chemical Name:
- ADRENORPHIN
- Synonyms
- METORPHIN;ADRENORPHIN;METORPHAMIDE;METORPHINAMIDE;adrenorphin amide;Adrenorphin(3TFA);Adrenorphin (human);ADRENORPHIN (BOVINE);Adrenorphin (metorphamide);Tyr-Gly-Gly-Phe-Arg-Arg-Val-NH2
- CBNumber:
- CB8129589
- Molecular Formula:
- C44H69N15O9S
- Molecular Weight:
- 984.18
- MDL Number:
- MFCD00065523
- MOL File:
- 88377-68-8.mol
- MSDS File:
- SDS
ADRENORPHIN price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Alfa Aesar | J66403 | Adrenorphin | 88377-68-8 | 1mg | $48.5 | 2021-12-16 | Buy |
Alfa Aesar | J66403 | Adrenorphin | 88377-68-8 | 5mg | $166 | 2021-12-16 | Buy |
ApexBio Technology | A1032 | Adrenorphin | 88377-68-8 | 25mg | $175 | 2021-12-16 | Buy |
ChemScene | CS-0027637 | Adrenorphin 95.49% | 88377-68-8 | 5mg | $210 | 2021-12-16 | Buy |
American Custom Chemicals Corporation | PEP0000414 | ADRENORPHIN 95.00% | 88377-68-8 | 1MG | $597.89 | 2021-12-16 | Buy |
ADRENORPHIN Chemical Properties,Uses,Production
Biological Activity
adrenorphin (metorphamide) is a potent inhibitor of nicotine-induced adrenaline and noradrenaline release with ic50 value of 10 μm [1].adrenorphin (metorphamide) is an endogenous, c-terminally amidated, opioid octapeptide (tyr-gly-gly-phe-met-arg-arg-val-nh2) that is produced from proteolytic cleavage of proenkephalin a and is widely distributed throughout the mammalian brain [2].adrenorphin (metorphamide) is selective nicotine-induced adrenaline and noradrenaline release inhibitor and has higher than 100-fold more potent than the reported nicotine-induced adrenaline and noradrenaline release inhibitor met5-enkephalin. when tested with bovine adrenal chromaffin cells, adrenorphin (metorphamide) showed inhibition on 5 μm nicotine-induced atp release by almost 50% at 5μm and the inhibition was not in a dose-dependent manner [1]. in bioassays and binding assays, metorphamide exhibited high μ-binding activity, as well as κ-binding activity with nearly half percent toμ-binding activity, while showed no activity on δ-binding [2].
References
[1]. marley, p.d., k.i. mitchelhill, and b.g. livett, metorphamide, a novel endogenous adrenal opioid peptide, inhibits nicotine-induced secretion from bovine adrenal chromaffin cells. brain res, 1986. 363(1): p. 10-7.
[2]. weber, e., et al., metorphamide: isolation, structure, and biologic activity of an amidated opioid octapeptide from bovine brain. proc natl acad sci u s a, 1983. 80(23): p. 7362-6.
ADRENORPHIN Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Alpha Biopharmaceuticals Co., Ltd | +86-411-39042497 +8613921981412 | sales@alphabiopharm.com | China | 886 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10247 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
Chengdu Youngshe Chemical Co., Ltd. | +8618108235634 | Cecilia@youngshechem.com | China | 2345 | 58 |
View Lastest Price from ADRENORPHIN manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2020-02-19 | ADRENORPHIN
88377-68-8
|
US $7.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
- ADRENORPHIN
88377-68-8
- US $7.00 / KG
- 99%
- Career Henan Chemical Co