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LYCOPSAMINE

CAS No.
10285-07-1
Chemical Name:
LYCOPSAMINE
Synonyms
Lycopsamin;Ccris 9199;Ccirs 9199;LYCOPSAMINE;(+)-Lycopsamine Hydrochloride;(+)-Lycopsamine Discontinued, see L487545;(2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(7R)-7β-hydroxy-5,6,7,7aα-tetrahydro-3H-pyrrolizine-1-yl]methyl ester;(2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizine-7-yl]methyl ester;(1R-(1alpha,7(2S*,3S*),7Abeta))-(2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl 2,3-dihydroxy-2-(1-methylethyl)butanoate;Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, ((1R,7ar)-2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (2S,3S)-
CBNumber:
CB81411830
Molecular Formula:
C15H25NO5
Molecular Weight:
299.36
MDL Number:
MFCD09260181
MOL File:
10285-07-1.mol
Last updated:2023-07-12 16:29:29

LYCOPSAMINE Properties

Melting point 41-44°C
Boiling point 463.3±45.0 °C(Predicted)
Density 1.26±0.1 g/cm3 (20 ºC 760 Torr)
storage temp. -20°C
solubility Chloroform, Ethanol
pka 12.59±0.29(Predicted)
form Solid
color Off-White
FDA UNII UER4ET3OHI

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS06
Signal word  Danger
Hazard statements  H300+H310
Precautionary statements  P262-P280-P301+P310+P330-P302+P352+P310
RIDADR  1544
HazardClass  6.1(b)
PackingGroup  III

LYCOPSAMINE price More Price(12)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich PHL89726 Lycopsamine phyproof? Reference Substance 10285-07-1 10MG $953 2023-06-20 Buy
AK Scientific 7819CA Lycopsamine 10285-07-1 10mg $1062 2021-12-16 Buy
Biosynth Carbosynth FL161608 Lycopsamine 10285-07-1 25mg $1600 2021-12-16 Buy
AK Scientific 7819CA Lycopsamine 10285-07-1 25mg $2210 2021-12-16 Buy
Biosynth Carbosynth FL161608 Lycopsamine 10285-07-1 50mg $2520 2021-12-16 Buy
Product number Packaging Price Buy
PHL89726 10MG $953 Buy
7819CA 10mg $1062 Buy
FL161608 25mg $1600 Buy
7819CA 25mg $2210 Buy
FL161608 50mg $2520 Buy

LYCOPSAMINE Chemical Properties,Uses,Production

Description

This amorphous pyrrolizidine alkaloid has been isolated from Arnsinckia hispida (Ruiz et Pav.) Johnst., A. interrnedia Fisch & Mey, and A. lycopsoides Lehm. It is dextrorotatory having [α]20D + 3.1 ° (c 5.98, EtOH). Alkaline hydrolysis yields retronecine and viridifloric acid.

Uses

(+)-Lycopsamine, occurs in pyrrolizidine alkaloid-containing plants, which are the most common poisonous plants affecting livestock, wildlife, and humans. Thye are being known as hepatotoxins and tumorigens.It has been shown that pyrrolizidine Alkaloid-Derived DNA Adducts, are the common biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation.

Uses

(+)-Lycopsamine, occurs in pyrrolizidine alkaloid-containing plants, which are the most common poisonous plants affecting livestock, wildlife, and humans. Thye are being known as hepatotoxins and tumorigens. It has been shown that pyrrolizidine Alkaloid-Derived DNA Adducts, are the common biological biomarker of pyrrolizidine alkaloid-induced liver tumor formation.

Definition

ChEBI: Lycopsamine is a member of pyrrolizines.

General Description

This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG

References

Cu1venor, Smith., Austral. 1. Chern., 19, 1955 (1966)

LYCOPSAMINE Preparation Products And Raw materials

Raw materials

Preparation Products

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LYCOPSAMINE (2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(1R,7aR)-2,3,5,7a-tetrahydro-1-hydroxy-1H-pyrrolizine-7-yl]methyl ester (2S,3S)-2,3-Dihydroxy-2-isopropylbutanoic acid [(7R)-7β-hydroxy-5,6,7,7aα-tetrahydro-3H-pyrrolizine-1-yl]methyl ester (1R-(1alpha,7(2S*,3S*),7Abeta))-(2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl 2,3-dihydroxy-2-(1-methylethyl)butanoate Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, ((1R,7ar)-2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (2S,3S)- Butanoic acid, 2,3-dihydroxy-2-(1-methylethyl)-, (2,3,5,7A-tetrahydro-1-hydroxy-1H-pyrrolizin-7-yl)methyl ester, (1R-(1alpha,7(2S*,3S*),7abeta))- Ccirs 9199 Ccris 9199 Lycopsamin (+)-Lycopsamine Discontinued, see L487545 (+)-Lycopsamine Hydrochloride 10285-07-1 Amines, Heterocycles