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ChemicalBook >> CAS DataBase List >>4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Structure
4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine structure
CAS No.
35808-68-5
Chemical Name:
4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
Synonyms
NSC 344519;4-Chloro-6-Methyl-7H-pyrr...;4-chloro-6-methyl-1H-pyrrolo[2,3-d]pyrimidine;4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine;7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-6-methyl-;1H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-6-methyl-
CBNumber:
CB82471237
Molecular Formula:
C7H6ClN3
Molecular Weight:
167.6
MDL Number:
MFCD09033903
MOL File:
35808-68-5.mol
MSDS File:
SDS
Last updated:2026-05-28 03:52:53
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4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Properties

Boiling point 292.2±50.0 °C(Predicted)
Density 1.51±0.1 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
pka 11.49±0.40(Predicted)
Appearance Off-white to light yellow Solid

SAFETY

Risk and Safety Statements

Symbol(GHS)  Exclamation Mark (GHS07)
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
HS Code  2933599590

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine price More Price(43)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Apolloscientific OR301210 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine 97% 35808-68-5 50mg $32 2026-06-04 Buy
Apolloscientific OR301210 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine 97% 35808-68-5 100mg $41 2026-06-04 Buy
Apolloscientific OR301210 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine 97% 35808-68-5 250mg $49 2026-06-04 Buy
Apolloscientific OR301210 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine 97% 35808-68-5 1g $131 2026-06-04 Buy
Apolloscientific OR301210 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine 97% 35808-68-5 5g $472 2026-06-04 Buy
Product number Packaging Price Buy
OR301210 50mg $32 Buy
OR301210 100mg $41 Buy
OR301210 250mg $49 Buy
OR301210 1g $131 Buy
OR301210 5g $472 Buy

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Chemical Properties, Uses, Production

Synthesis

7-Benzenesulfonyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyri midine

252723-16-3

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine

35808-68-5

Synthesis of compound 18.3. A mixture of potassium tert-butoxide (450 mg, 4 mmol) and 7-benzenesulfonyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (250 mg, 0.8 mmol) in tetrahydrofuran (7.5 mL) was stirred for 16 hours at room temperature. After completion of the reaction, saturated sodium bicarbonate solution was added to the reaction mixture. The reaction mixture was extracted with ethyl acetate (3 × 100 mL), the organic layers were combined, washed sequentially with water and saturated brine, dried over anhydrous sodium sulfate, and concentrated under reduced pressure. The residue was purified by fast column chromatography with petroleum ether/ethyl acetate (100/0 to 0/100, v/v) as eluent to afford 4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine (Compound 18.3, 118 mg, 87% yield).1H NMR (200 MHz, DMSO-d6) δ 12.5 (br s, 1H) 8.47 (s, 1H), 6.29 (s, 1H), 2.42 (s, 3H). Mass spectrum (MS) m/z 168 [M + H]+.

References

[1] Patent: US2009/5359, 2009, A1. Location in patent: Page/Page column 26
[2] Beilstein Journal of Organic Chemistry, 2016, vol. 12, p. 1103 - 1110
[3] Patent: WO2012/158795, 2012, A1. Location in patent: Page/Page column 102
[4] Patent: WO2012/158764, 2012, A1. Location in patent: Page/Page column 215-216
[5] Patent: WO2013/191965, 2013, A1. Location in patent: Page/Page column 191

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Preparation Products And Raw materials

Raw materials

4H-Pyrrolo[2,3-d]pyrimidin-4-one, 1,7-dihydro-6-methyl- (9CI) 7-Benzenesulfonyl-4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyri midine Potassium Tetrahydrofuran Recombinant Human Telomerase

Preparation Products

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Suppliers

Global Suppliers ( 97)
Supplier Tel Email Country ProdList Advantage
Pure Chemistry Scientific Inc. 001-857-928-2050 or 1-888-588-9418 sales@chemreagents.com United States 10174 62
Tetranov Biopharm 13526569071 sales@leadmedpharm.com China 7880 64
Nanjing Chemlin Chemical Co., Ltd 025-83697070 13770331960 info@chemlin.com.cn China 16307 64
Shanghai yirong biology science and technology co., ltd 18049974220 3060526242@qq.com China 999 60
Wuhan ariel chemical Co., LTD. 18986259541 18986259541 sales@3stc.com China 3797 58
Dtchem Laboratories,（Gan Su）Co.,Ltd. 18993961550 18993966060 sales@techbiochem.com China 768 61
Shanghai Jian Chao Chemical Technology Co., Ltd. 150-2103-5486 18017383231 983544897@qq.com China 9335 55
9ding chemical ( Shanghai) Limited 4009209199 sales@9dingchem.com China 18201 56
Runpharm Technology Limited 18171398856 2968382473 service@runpharm.com China 716 55
Wuhan Kaymke Chemical Co., Ltd., 027-87342388 18086026008 sales@kaymke.com China 3525 55
Supplier Advantage
Pure Chemistry Scientific Inc. 62
Tetranov Biopharm 64
Nanjing Chemlin Chemical Co., Ltd 64
Shanghai yirong biology science and technology co., ltd 60
Wuhan ariel chemical Co., LTD. 58
Dtchem Laboratories,（Gan Su）Co.,Ltd. 61
Shanghai Jian Chao Chemical Technology Co., Ltd. 55
9ding chemical ( Shanghai) Limited 56
Runpharm Technology Limited 55
Wuhan Kaymke Chemical Co., Ltd., 55

View Latest Price from 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine pictures 2020-05-17 4-chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
35808-68-5
 $1.00 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine pictures 2020-01-03 4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine
35808-68-5
 $1.00 1KG 95-99% 1ton Career Henan Chemical Co

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine Spectrum

4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine(35808-68-5)1HNMR

35808-68-5 (4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine) Related Search:

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4-Chloro-6-methyl-7H-pyrrolo[2,3-d]pyrimidine 4-chloro-6-methyl-1H-pyrrolo[2,3-d]pyrimidine NSC 344519 1H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-6-methyl- 4-Chloro-6-Methyl-7H-pyrr... 7H-Pyrrolo[2,3-d]pyrimidine, 4-chloro-6-methyl- 35808-68-5 Heterocycle-Pyrimidine series