4-Chloro-8-aminoquinoline
- CAS No.
- 81764-16-1
- Chemical Name:
- 4-Chloro-8-aminoquinoline
- Synonyms
- 4-Chloroquinolin-8-aMine;4-Chloro-8-quinolylaMine;4-Chloro-8-aminoquinoline;8-Amino-4-chloroquinoline;8-Quinolinamine, 4-chloro-
- CBNumber:
- CB82537625
- Molecular Formula:
- C9H7ClN2
- Molecular Weight:
- 178.62
- MDL Number:
- MFCD18448245
- MOL File:
- 81764-16-1.mol
| Product description | Number | Pack Size | Price |
| 4-Chloroquinolin-8-amine 95% | OR931277 | 1g | $135 |
| 4-Chloroquinolin-8-amine 95% | 3H30-5-9W | 1g | $216 |
| 4-CHLOROQUINOLIN-8-AMINE 95.00% | HCH0366222 | 5MG | $501.42 |
| 4-Chloroquinolin-8-amine 95% | OR931277 | 5g | $555 |
| 4-Chloroquinolin-8-amine | 2667AC | 10g | $563 |
| More product size | |||
4-Chloro-8-aminoquinoline price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Apolloscientific | OR931277 | 4-Chloroquinolin-8-amine 95% | 81764-16-1 | 1g | $135 | 2021-12-16 | Buy |
| SynQuest Laboratories | 3H30-5-9W | 4-Chloroquinolin-8-amine 95% | 81764-16-1 | 1g | $216 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | HCH0366222 | 4-CHLOROQUINOLIN-8-AMINE 95.00% | 81764-16-1 | 5MG | $501.42 | 2021-12-16 | Buy |
| Apolloscientific | OR931277 | 4-Chloroquinolin-8-amine 95% | 81764-16-1 | 5g | $555 | 2021-12-16 | Buy |
| AK Scientific | 2667AC | 4-Chloroquinolin-8-amine | 81764-16-1 | 10g | $563 | 2021-12-16 | Buy |
4-Chloro-8-aminoquinoline Chemical Properties,Uses,Production
Chemical Properties
Yellow solid
Synthesis
23833-99-0
81764-16-1
GENERAL METHOD: 4-Chloro-8-nitroquinoline (90 mg, 0.292 mmol) was dissolved in ethanol (2 mL) and iron powder (163 mg, 2.92 mmol) and ammonium chloride (127 mg, 2.33 mmol) were added sequentially. The reaction mixture was heated and refluxed for 2 hours. Upon completion of the reaction, the reaction mixture was filtered through diatomaceous earth and the diatomaceous earth bed was washed with a chloroform solution of 10% methanol. The filtrate was washed sequentially with saturated aqueous sodium bicarbonate solution and pure water. The organic layer was separated, dried over anhydrous sodium sulfate and filtered, and concentrated to give 70 mg of the target product 4-chloro-8-aminoquinoline. The product was confirmed by 1H NMR (300 MHz, DMSO-d6) and mass spectrometry (MS). Synthesis of 4-chloro-8-aminoquinoline: 200 mg of the target product was obtained by reaction using a mixed solution of ethanol (6 mL) and water (3 mL) of 4-chloro-8-nitroquinoline (250 mg, 1.20 mmol), ammonium chloride (513 mg, 9.60 mmol), and iron powder (671 mg, 12.0 mmol) according to the above general method. The product was confirmed by 1H NMR (400 MHz, CDCl3) and mass spectrometry (MS).
References
[1] Dalton Transactions, 2012, vol. 41, # 38, p. 11776 - 11782
[2] Journal of the American Chemical Society, 1947, vol. 69, p. 303,306
[3] Journal of the American Chemical Society, 1946, vol. 68, p. 1524,1526
[4] Patent: US2013/210844, 2013, A1. Location in patent: Paragraph 0322; 0517; 0518
4-Chloro-8-aminoquinoline Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63687 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30229 | 58 |
| HANGZHOU LEAP CHEM CO., LTD. | +86-571-87711850 | market18@leapchem.com | China | 43339 | 58 |
| Nanjing Bicbiotechnology Co., Ltd | +86-2552131256 +86-18251840740 | sales@bicbiotech.com | China | 5994 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52923 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Alputon Inc. | 021-60753308-14013 | China | 137 | 55 | |
| Shanghai Carlow Chemicals Co., Ltd. | 21-33526724 18930996265 | info@carlowchem.com | China | 1922 | 58 |
| Bide Pharmatech Ltd. | 400-164-7117 13681763483 | product02@bidepharm.com | China | 39966 | 60 |
| ShangHai AmK Pharmaceutical Technology Co., Ltd. | 微信 17321281695 18019252918 | sale@amkchem.com | China | 15136 | 55 |
