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CAY10526

CAY10526 structure

CAS No.: 938069-71-7

Chemical Name:: CAY10526

Synonyms: CAY10526;CAY10526 Exclusive;2(5H)-Furanone, 4-benzo[b]thien-2-yl-3-bromo-5-hydroxy-;3-(1-benzothiophen-2-yl)-4-bromo-2-hydroxy-2H-furan-5-one;4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one;WM793,PGE2 production,Inhibitor,inhibit,SB2,microsomal PGE2 synthase-1,A375,cleaved caspase 3,CAY10526,increases apoptosis,increases BAX and BAK,pro-apoptotic,anti-apoptotic,melanoma xenografts,mPGES1 inhibitor,PGE synthase,Prostaglandin E synthase

CBNumber:: CB82590422

Molecular Formula:: C12H7BrO3S

Molecular Weight:: 311.15

MDL Number:: MFCD18432686

MOL File:: 938069-71-7.mol

Last updated:2023-05-21 10:59:17

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CAY10526 Properties

Boiling point	561.7±50.0 °C(Predicted)
Density	1.889±0.06 g/cm3(Predicted)
storage temp.	Store at -20°C
solubility	DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 1 mg/ml
form	A crystalline solid
pka	8.90±0.60(Predicted)

CAY10526 price More Price(4)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Cayman Chemical	10010088	CAY10526 ≥98%	938069-71-7	1mg	$57	2024-03-01	Buy
Cayman Chemical	10010088	CAY10526 ≥98%	938069-71-7	5mg	$249	2024-03-01	Buy
Cayman Chemical	10010088	CAY10526 ≥98%	938069-71-7	10mg	$437	2024-03-01	Buy
AK Scientific	1400AH	4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one	938069-71-7	1mg	$160	2021-12-16	Buy

Product number	Packaging	Price	Buy
10010088	1mg	$57	Buy
10010088	5mg	$249	Buy
10010088	10mg	$437	Buy
1400AH	1mg	$160	Buy

CAY10526 Chemical Properties,Uses,Production

Description

Prostaglandin E₂ (PGE₂) is the major PG synthesized at sites of inflammation and plays an important role in different inflammatory diseases. It acts as a mediator of pain and inflammation and promotes bone destruction. The increased synthesis of PGE₂ during inflammation can be accounted for by increased expression of both cyclooxygenase-2 (COX-2) and microsomal PGE synthase-1 (mPGES-1). CAY10526 is an inhibitor of PGE₂ production through the selective modulation of mPGES-1 expression. It dose-dependently inhibits PGE₂ production in lipopolysaccharide-stimulated RAW 264.7 cells with an IC₅₀ value of 1.8 μM without any effect on COX-2 expression.

CAY10526 Preparation Products And Raw materials

Raw materials

Preparation Products

CAY10526 Suppliers

Global( 43)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	19892	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	+86-057181025280; +8617767106207	sales@molcore.com	China	49739	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	+86-18341751992 +86-15382112998	757984502@qq.com	China	892	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Shanghai Beckham Medical Technology Co., Ltd	021-13816613772 13816613772	huahero21@sina.com	China	358	55
Shanghai EFE Biological Technology Co., Ltd.	021-65675885 18964387627	info@efebio.com	China	9709	58
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2985	58
Shanghai Han-Xiang Chemical Co., Ltd.	15971444841	amber@biochempartner.com	China	3063	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	0571-85361029	synstar518@163.com	China	1991	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Hangzhou MolCore BioPharmatech Co.,Ltd.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd	58
Aladdin Scientific	58
Shanghai Beckham Medical Technology Co., Ltd	55
Shanghai EFE Biological Technology Co., Ltd.	58
Shanghai Rechem science Co., Ltd.	58
Shanghai Han-Xiang Chemical Co., Ltd.	58
Hangzhou Synstar pharmaceutical Technology CO.,Ltd	58

CAY10526 CAY10526 Exclusive 3-(1-benzothiophen-2-yl)-4-bromo-2-hydroxy-2H-furan-5-one 2(5H)-Furanone, 4-benzo[b]thien-2-yl-3-bromo-5-hydroxy- WM793,PGE2 production,Inhibitor,inhibit,SB2,microsomal PGE2 synthase-1,A375,cleaved caspase 3,CAY10526,increases apoptosis,increases BAX and BAK,pro-apoptotic,anti-apoptotic,melanoma xenografts,mPGES1 inhibitor,PGE synthase,Prostaglandin E synthase 4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one 938069-71-7