CAY10526
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- $57 - $618
- Product name: CAY10526
- CAS: 938069-71-7
- MF: C12H7BrO3S
- MW: 311.15
- EINECS:
- MDL Number:MFCD18432686
- Synonyms:CAY10526;CAY10526 Exclusive;3-(1-benzothiophen-2-yl)-4-bromo-2-hydroxy-2H-furan-5-one;2(5H)-Furanone, 4-benzo[b]thien-2-yl-3-bromo-5-hydroxy-;WM793,PGE2 production,Inhibitor,inhibit,SB2,microsomal PGE2 synthase-1,A375,cleaved caspase 3,CAY10526,increases apoptosis,increases BAX and BAK,pro-apoptotic,anti-apoptotic,melanoma xenografts,mPGES1 inhibitor,PGE synthase,Prostaglandin E synthase;4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxyfuran-2(5H)-one;CAY10526, 10 mM in DMSO;4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one
6 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
- Sigma-Aldrich
Package
- 1mg
- 5mg
- 10mg
- 5 mg
- 25 mg
- ManufacturerAK Scientific
- Product number1400AH
- Product description4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one
- Packaging1mg
- Price$160
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number10010088
- Product descriptionCAY10526 ≥98%
- Packaging1mg
- Price$57
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010088
- Product descriptionCAY10526 ≥98%
- Packaging5mg
- Price$249
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number10010088
- Product descriptionCAY10526 ≥98%
- Packaging10mg
- Price$437
- Updated2024-03-01
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML2530
- Product descriptionCAY10526 ≥98% (HPLC)
- Packaging5 mg
- Price$186.2
- Updated2025-07-31
- Buy
- ManufacturerSigma-Aldrich
- Product numberSML2530
- Product descriptionCAY10526 ≥98% (HPLC)
- Packaging25 mg
- Price$618
- Updated2025-07-31
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 1400AH | 4-(Benzo[b]thiophen-2-yl)-3-bromo-5-hydroxydihydrofuran-2(3H)-one | 1mg | $160 | 2021-12-16 | Buy |
| Cayman Chemical | 10010088 | CAY10526 ≥98% | 1mg | $57 | 2024-03-01 | Buy |
| Cayman Chemical | 10010088 | CAY10526 ≥98% | 5mg | $249 | 2024-03-01 | Buy |
| Cayman Chemical | 10010088 | CAY10526 ≥98% | 10mg | $437 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2530 | CAY10526 ≥98% (HPLC) | 5 mg | $186.2 | 2025-07-31 | Buy |
| Sigma-Aldrich | SML2530 | CAY10526 ≥98% (HPLC) | 25 mg | $618 | 2025-07-31 | Buy |
Properties
Boiling point :561.7±50.0 °C(Predicted)
Density :1.889±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :8.90±0.60(Predicted)
color :Off-white to yellow
Density :1.889±0.06 g/cm3(Predicted)
storage temp. :Store at -20°C
solubility :DMF: 30 mg/ml; DMSO: 30 mg/ml; DMSO:PBS (pH 7.2) (1:1): 0.5 mg/ml; Ethanol: 1 mg/ml
form :A crystalline solid
pka :8.90±0.60(Predicted)
color :Off-white to yellow
Safety Information
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Description
CAY10526 is an inhibitor of PGE2 production through the selective modulation of mPGES-1 expression. It dose-dependently inhibits PGE2 production in lipopolysaccharide-stimulated RAW 264.7 cells with an IC50 value of 1.8 μM without any effect on COX-2 expression.Suppliers and manufacturers
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