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Betamethasone 17-Propionate 21-Mesylate

CAS No.
15423-80-0
Chemical Name:
Betamethasone 17-Propionate 21-Mesylate
Synonyms
Clobetasol Propionate EP IMP I;Clobetasol Propionate EP Impurity I;BetaMethasone 17-Propionate 21-Mesylate;Clobetasol Propionate Impurity 9(Clobetasol Propionate EP Impurity I);Clobetasol Propionate EP Impurity I (Betamethasone 17-Propionate 21-Mesylate);Clobetasol Propionate Impurity-I (EP) (Betamethasone 17-Propionate 21-Mesylate);9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (betamethasone),;9-Fluoro-11β,17,21-trihydroxy-16β-Methylpregna-1,4-diene-3,20-dione 21-Methanesulfonate 17-Propionate;9-Fluoro-11β,17,21-trihydroxy-16β-Methylpregna-1,4-diene-3,20-dione 21-Methanesulfonate 17-Propionate;(11β,16β)-9-Fluoro-11-hydroxy-16-Methyl-21-[(Methylsulfonyl)oxy]-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione
CBNumber:
CB82621700
Molecular Formula:
C26H35FO8S
Molecular Weight:
526.61
MDL Number:
MFCD29045134
MOL File:
15423-80-0.mol
Last updated:2023-04-23 13:52:06

Betamethasone 17-Propionate 21-Mesylate Properties

Melting point 177-179 °C(Solv: water (7732-18-5); ethanol (64-17-5))
Boiling point 659.2±55.0 °C(Predicted)
Density 1.33±0.1 g/cm3(Predicted)
storage temp. Hygroscopic, -20°C Freezer, Under inert atmosphere
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Very Slightly)
form Solid
pka 12.87±0.70(Predicted)
color Pale Yellow to Yellow
Stability Hygroscopic
FDA UNII GA4A80ZP11

Betamethasone 17-Propionate 21-Mesylate price More Price(2)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B327070 Betamethasone17-Propionate21-Mesylate 15423-80-0 5mg $155 2021-12-16 Buy
Medical Isotopes, Inc. 63160 Betamethasone17-propionate21-mesylate 15423-80-0 1mg $190 2021-12-16 Buy
Product number Packaging Price Buy
B327070 5mg $155 Buy
63160 1mg $190 Buy

Betamethasone 17-Propionate 21-Mesylate Chemical Properties,Uses,Production

Uses

Betamethasone 17-Propionate 21-Mesylate is the 21-mesylate analogue of Betamethasone 17-Acetate (B327015) with antiinflammatory activity.

Betamethasone 17-Propionate 21-Mesylate Preparation Products And Raw materials

Raw materials

Preparation Products

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(11β,16β)-9-Fluoro-11-hydroxy-16-Methyl-21-[(Methylsulfonyl)oxy]-17-(1-oxopropoxy)pregna-1,4-diene-3,20-dione 9-Fluoro-11β,17,21-trihydroxy-16β-Methylpregna-1,4-diene-3,20-dione 21-Methanesulfonate 17-Propionate BetaMethasone 17-Propionate 21-Mesylate Clobetasol Propionate EP Impurity I Clobetasol Propionate Impurity 9(Clobetasol Propionate EP Impurity I) [(8S,9R,10S,11S,13S,14S,16S,17R)-9-fluoro-11-hydroxy-10,13,16-trimethyl-17-(2-methylsulfonyloxyacetyl)-3-oxo-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl] propanoate Clobetasol Propionate EP IMP I Pregna-1,4-diene-3,20-dione, 9-fluoro-11-hydroxy-16-methyl-21-[(methylsulfonyl)oxy]-17-(1-oxopropoxy)-, (11β,16β)- 9-Fluoro-11β,17,21-trihydroxy-16β-Methylpregna-1,4-diene-3,20-dione 21-Methanesulfonate 17-Propionate Clobetasol Propionate Impurity-I (EP) (Betamethasone 17-Propionate 21-Mesylate) 9-fluoro-11β,17,21-trihydroxy-16β-methylpregna-1,4-diene-3,20-dione (betamethasone), (8S,9R,10S,11S,13S,14S,16S,17R)-9-Fluoro-11-hydroxy-10,13,16-trimethyl-17-(2-((methylsulfonyl)oxy)acetyl)-3-oxo-6,7,8,9,10,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-17-yl propionate (Clobetasol Propionate Impurity) Clobetasol Propionate EP Impurity I (Betamethasone 17-Propionate 21-Mesylate) 15423-80-0 C26H35FO8S Impurities Intermediates & Fine Chemicals Pharmaceuticals Steroids Impurities, Pharmaceuticals, Intermediates & Fine Chemicals, Steroids