Seletalisib
- CAS No.
- 1362850-20-1
- Chemical Name:
- Seletalisib
- Synonyms
- UCB5857;Seletalisib;UCB-5857;UCB5857;Seletalisib(UCB-5857);Seletalisib, 10 mM in DMSO;UCB5857; UCB-5857; UCB 5857;Seletalisib (UCB-5857) ，S8560;Inhibitor,Phosphoinositide 3-kinase,Seletalisib,UCB-5857,UCB 5857,inhibit,PI3K;(R)-3-(8-Chloro-3-(2,2,2-trifluoro-1-(pyrido[3,2-d]pyrimidin-4-ylamino)ethyl)quinolin-2-yl)pyridine 1-oxide;Pyrido[3,2-d]pyrimidin-4-amine, N-[(1R)-1-[8-chloro-2-(1-oxido-3-pyridinyl)-3-quinolinyl]-2,2,2-trifluoroethyl]-
- CBNumber:
- CB83171699
- Molecular Formula:
- C23H14ClF3N6O
- Molecular Weight:
- 482.85
- MDL Number:
- MFCD28963973
- MOL File:
- 1362850-20-1.mol
- MSDS File:
- SDS
- TDS File:
- TDS
| Boiling point | 710.8±60.0 °C(Predicted) |
|---|---|
| Density | 1.53±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO : ≥ 83.3 mg/mL (172.52 mM) |
| form | Solid |
| pka | 3.55±0.30(Predicted) |
| color | White to off-white |
| FDA UNII | 64CW205BDD |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
Seletalisib price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Biosynth | MEC85020 | Seletalisib (UCB-5857) | 1362850-20-1 | 5mg | $756.5 | 2026-06-04 | Buy |
| Biosynth | MEC85020 | Seletalisib (UCB-5857) | 1362850-20-1 | 10mg | $1210.4 | 2026-06-04 | Buy |
| Biosynth | MEC85020 | Seletalisib (UCB-5857) | 1362850-20-1 | 25mg | $1973.25 | 2026-06-04 | Buy |
| Biosynth | MEC85020 | Seletalisib (UCB-5857) | 1362850-20-1 | 50mg | $3157.5 | 2026-06-04 | Buy |
| ChemScene | CS-6470 | Seletalisib 99.79% | 1362850-20-1 | 5mg | $162 | 2026-06-04 | Buy |
Seletalisib Chemical Properties, Uses, Production
Uses
Seletalisib (UCB5857) is potent and selective PI3Kδ inhibitor with an IC50 of 12 nM.
in vivo
Seletalisib significantly inhibits IL-2 release following TCR stimulation in the rat. The inhibition is observed at all tested doses of seletalisib with almost complete inhibition reached at dose levels ≥1 mg/kg. Seletalisib has potent in vivo effects with an estimated IC50 value of <10 nM[1].
IC 50
PI3Kδ: 12 nM (IC50)
References
[1] Allen RA, et al. Seletalisib: Characterization of a Novel, Potent, and Selective Inhibitor of PI3Kδ. J Pharmacol Exp Ther. 2017 Apr 25. pii: jpet.116.237347. DOI:10.1124/jpet.116.237347
Seletalisib Preparation Products And Raw materials
Raw materials
Preparation Products
Seletalisib Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Boyle Chemical Co., Ltd. | sales@boylechem.com | China | 2915 | 55 | |
| Shanghai Jian Chao Chemical Technology Co., Ltd. | 150-2103-5486 18017383231 | 983544897@qq.com | China | 9335 | 55 |
| MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4853 | 58 |
| ShangHai Caerulum Pharma Discovery Co., Ltd. | 18149758185 18149758185 | sales-cpd@caerulumpharma.com | China | 3493 | 58 |
| DKMbiochem.Co. Ltd | 15901859516 | sales@DKMbiochem.com | China | 361 | 58 |
| Sichuan Wei Keqi Biological Technology Co., Ltd. | 028-81700200 18116577057 | 3003855609@qq.com | China | 7717 | 56 |
| Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696，15000506266 15000506266 | China | 4865 | 55 | |
| Shanghai YuanYe Biotechnology Co., Ltd. | 15026964105 | 2881489226@qq.com | China | 87240 | 60 |
| ShangHai Biochempartner Co.,Ltd | 177-54423994 17754423994 | 2853530910@QQ.com | China | 7996 | 62 |
| Shanghai Rechem science Co., Ltd. | 021-31433387 15618786686 | sales@rechemscience.com | China | 2960 | 58 |
View Latest Price from Seletalisib manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2026-07-27 | Seletalisib
1362850-20-1
|
$52.00-198.00 | 99.81% | 10g | TargetMol Chemicals Inc. |
-
- Seletalisib
1362850-20-1
- $52.00-198.00
- 99.81%
- TargetMol Chemicals Inc.
