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Ammonium acetate

CAS No.
631-61-8
Chemical Name:
Ammonium acetate
Synonyms
NH4OAC;Ammonium ethanoate;Ammoniumacetat;Ammonium aletate;acetated’ammonium;NH Ac;KH2PO44;MARKER DNA 1KBP;AMMONIUM ACETATE;ACS,Reag. Ph Eur
CBNumber:
CB8438173
Molecular Formula:
C2H7NO2
Molecular Weight:
77.08
MDL Number:
MFCD00013066
MOL File:
631-61-8.mol
MSDS File:
SDS
Last updated:2026-01-13 11:26:02
Product description Number Pack Size Price
Ammonium acetate for mass spectrometry, LiChropur?, eluent additive for LC-MS 73594 25g $179
Ammonium acetate for mass spectrometry, LiChropur?, eluent additive for LC-MS 73594 100g $636
Ammonium acetate for HPLC LiChropur? 5.43834 100g $148
Ammonium acetate for HPLC LiChropur? 5.43834 250g $320
Ammonium acetate for LC-MS LiChropur? 5.33004 50g $230
More product size

Ammonium acetate Properties

Melting point 110-112 °C (dec.) (lit.)
Boiling point 138.46°C (rough estimate)
Density 1.07 g/mL at 20 °C
bulk density 410kg/m3
vapor pressure 0.017-0.02Pa at 25℃
refractive index 1.4350 (estimate)
Flash point 136 °C
storage temp. Store at +15°C to +25°C.
solubility H2O: 1 M at 20 °C, clear, colorless
form Solid
pka 4.6(Acetic Acid), 9.3(Ammonium Hydroxide)(at 25℃)
color White
PH 7(1 mM solution);7(10 mM solution);7(100 mM solution);6.95(1000 mM solution)
PH Range 6.7 - 7.3
Odor Slight acetic acid odor
Water Solubility 1480 g/L (20 ºC)
Sensitive Hygroscopic
λmax λ: 260 nm Amax: 0.015
λ: 280 nm Amax: 0.01
Merck 14,495
BRN 4186741
Stability Hygroscopic
Cosmetics Ingredients Functions BUFFERING
InChI 1S/C2H4O2.H3N/c1-2(3)4;/h1H3,(H,3,4);1H3
InChIKey USFZMSVCRYTOJT-UHFFFAOYSA-N
SMILES N.CC(O)=O
LogP -2.79
Substances Added to Food (formerly EAFUS) AMMONIUM ACETATE
CAS DataBase Reference 631-61-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII RRE756S6Q2
NIST Chemistry Reference Ammonium acetate, anhydrous(631-61-8)
EPA Substance Registry System Ammonium acetate (631-61-8)
UNSPSC Code 12352302
NACRES NB.21

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319
Precautionary statements  P305+P351+P338
Safety Statements  24/25
RIDADR  UN 9079
WGK Germany  3
RTECS  AF3675000
3
TSCA  TSCA listed
HazardClass  9
HS Code  29152900
Storage Class 11 - Combustible Solids
Hazardous Substances Data 631-61-8(Hazardous Substances Data)
Toxicity LD i.v. in mice: 1.8 mg (NH4+)/20g (Welch)
Limited Quantities 5.0 L (1.3 gallons) (liquid) or 5.0 kg (11 lbs) (solid)
Excepted Quantities Max Inner Pack (30g or 30ml) and Max Outer Pack (1Kg or 1L)
NFPA 704
1
1 0

Ammonium acetate price More Price(109)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 73594 Ammonium acetate for mass spectrometry, LiChropur?, eluent additive for LC-MS 631-61-8 25g $179 2025-07-31 Buy
Sigma-Aldrich 73594 Ammonium acetate for mass spectrometry, LiChropur?, eluent additive for LC-MS 631-61-8 100g $636 2025-07-31 Buy
Sigma-Aldrich 5.43834 Ammonium acetate for HPLC LiChropur? 631-61-8 100g $148 2025-07-31 Buy
Sigma-Aldrich 5.43834 Ammonium acetate for HPLC LiChropur? 631-61-8 250g $320 2025-07-31 Buy
Sigma-Aldrich 5.33004 Ammonium acetate for LC-MS LiChropur? 631-61-8 50g $230 2025-07-31 Buy
Product number Packaging Price Buy
73594 25g $179 Buy
73594 100g $636 Buy
5.43834 100g $148 Buy
5.43834 250g $320 Buy
5.33004 50g $230 Buy

Ammonium acetate Chemical Properties,Uses,Production

Chemical Properties

Ammonium acetate is a white, deliquescent crystalline solid with a slightly acetic odor. It is used as a reagent in analytical chemistry for determining lead and iron content,a chemical intermediate in manufacturing acetamide. It is also a diuretic in veterinary medicine, in other drugs, in textile dyeing, in meat preservative, in foam rubbers, in vinyl plastics, in stripping explosives, and in determining lead and iron content.
Ammonium acetate

Physical properties

White crystalline solid; deliquescent; melts at 114°C; decomposes at elevated temperatures; density 1.17 g/cm3 at 20°C, density of a 10% solution 1.022 g/mL, and a 50% solution 1.092 g/mL; very soluble in cold water (1,480 g/L at 4°C); also soluble in cold alcohol and acetone (78.9 g/L in methanol at 15°C); solution loses ammonia on standing and becomes acidic.

Uses

Ammonium acetate solution can be used to study molecular biology, biological buffers, reagents and DNA and RNA purification. Ammonium acetate solution has been used to study pharmacokinetic analysis of α and β epimers of glycyrrhetinic acid in rat plasma. Ammonium acetate solution has also been used in a study to develop a method for the simultaneous determination of aristolochic acids A and B in some Chinese herbals and traditional Chinese patent medicines.

Uses

Ammonium acetate is a reagent used in chromatographic analysis of various compounds such as oligos, proteins, and peptides. It is also employed with acetic acid to provide a buffer solution. Generally it behaves as a catalyst in many reactions like Knoevenagel, Borch. It is also employed as a nutrient additive.

Uses

Ammonium acetate is used in the manufacture of acetamide and as a diuretic and diaphoretic in medical applications. The wool industry also uses this salt as a dye mordant.
Buffer solution; determination of lead and iron; separating lead sulfate from other sulfates.

Definition

ChEBI: Ammonium acetate is an ammonium salt obtained by reaction of ammonia with acetic acid. A deliquescent white crystalline solid, it has a relatively low melting point (114℃) for a salt. Used as a food acidity regulator, although no longer approved for this purpose in the EU. It has a role as a food acidity regulator and a buffer. It is an acetate salt and an ammonium salt.

Preparation

Ammonium acetate is manufactured by neutralizing acetic acid with ammonium carbonate or by passing ammonia gas into glacial acetic acid. Acidic ammonium acetate, CH3CO2NH4.CH3CO2H[25007-86-7], is manufactured by dissolving the neutral salt in acetic acid.

General Description

A white crystalline solid. The primary hazard is the threat to the environment. Immediate steps should be taken to limit its spread to the environment. Ammonium acetate is used in chemical analysis, in pharmaceuticals, in preserving foods, and for other uses.

Air & Water Reactions

Water soluble.

Reactivity Profile

Ammonium acetate causes the decomposition of sodium hypochlorite within a few seconds [Mellor 2 Supp. 1:550 1956].

Health Hazard

Inhalation of dust irritates nose and mouth. Ingestion irritates mouth and stomach. Contact with dust causes irritation of eyes and mild irritation of skin.

Fire Hazard

Special Hazards of Combustion Products: Irritating vapors of ammonia acetic acid, and nitrogen oxides may form in fires.

Flammability and Explosibility

Non flammable

Biochem/physiol Actions

Ammonium acetate can be used in proteinaceous baits and in beer waste to increase their attraction to Ceratitis capitate. It helps in the progression of acetone-butanol-ethanol (ABE) fermentation when it is used as the only nitrogen source.

Safety Profile

Poison by intravenous route. Moderately toxic by intraperitoneal route. When heated to decomposition it emits toxic fumes of NO, and NH3

Potential Exposure

Ammonium acetate is used as a chemical reagent, to make drugs; foam rubber; vinyl plastics; explosives, and to preserve foods. An environmental threat.

Shipping

UN3077 Environmentally hazardous substances, solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous hazardous material, Technical Name Required.

Purification Methods

Crystallise it twice from anhydrous acetic acid, and dry under vacuum for 24hours at 100o [Proll & Sutcliff Trans Faraday Soc 57 1078 1961].

Incompatibilities

Combustible solid. Incompatible with oxidizers (chlorates, nitrates, peroxides, permanganates, perchlorates, chlorine, bromine, fluorine, etc.); contact may cause fires or explosions. Keep away from alkaline materials, strong bases, strong acids, oxoacids, epoxides, sodium hypochlorite, potassium chlorate, sodium nitrite.

64-19-7
631-61-8
Synthesis of Ammonium acetate from Acetic acid

Ammonium acetate Preparation Products And Raw materials

Raw materials

Preparation Products

1of8

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Ammonium acetate pictures 2026-02-17 Ammonium acetate
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0.99 RongNa Biotechnology Co.,Ltd
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US $1.00 / KG 1KG 99% 10mt Hebei Chuanghai Biotechnology Co., Ltd
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US $0.10 / KG 1KG 98.0% 1000Tons Shaanxi Dideu Medichem Co. Ltd
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