DIMETHISTERONE
- CAS No.
- 79-64-1
- Chemical Name:
- DIMETHISTERONE
- Synonyms
- Ovin;P 5048;Lutogan;Secrosteron;DIMETHISTERONE;DIMETHISTERONE USP/EP/BP;6α,21-Dimethylethisterone;6α-Methyl-17-(1-propynyl)testosterone;17β-Hydroxy-6α-methyl-17-(1-propynyl)androst-4-en-3-one;Androst-4-en-3-one,17-hydroxy-6-methyl-17-(1-propynyl)-, (6a,17b)-
- CBNumber:
- CB8702265
- Molecular Formula:
- C23H32O2
- Molecular Weight:
- 340.5
- MDL Number:
- MFCD00867870
- MOL File:
- 79-64-1.mol
- MSDS File:
- SDS
Melting point | 102° |
---|---|
alpha | D20 +10° (c = 1 in chloroform) |
Boiling point | 416.28°C (rough estimate) |
Density | 1.0555 (rough estimate) |
refractive index | 1.4480 (estimate) |
pka | 13.03±0.70(Predicted) |
FDA UNII | OIC9M646C5 |
EPA Substance Registry System | Dimethisterone (79-64-1) |
DIMETHISTERONE Chemical Properties,Uses,Production
Originator
Oracon,Mead Johnson,US,1965
Uses
Dimethisterone-d3 is the labeled analogue of Dimethisterone (D460430), an oral contraceptive steroid.
Definition
ChEBI: Dimethisterone is a 3-hydroxy steroid. It has a role as an androgen.
Manufacturing Process
A solution of a Grignard reagent, employing 1-propyne (8 grams) was prepared. To this reagent there was added the 3,3 ethylenedioxy derivative (4 grams) of 6-α-methylandrost-4-ene-3,17-dione in tetrahydrofuran (100 ml), and the mixture heated under reflux for 3 hours. After decomposition of the complex with aqueous ammonium chloride, the product was isolated with ether and treated with 90% acetic acid (50 ml) for 30 minutes at 100°C. The product obtained by pouring the mixture into water and extracting with ether was crystallized from aqueous methanol. 17β-Hydroxy-6α-methyl-17α-(prop- 1-ynyl)androst-4-en-3-one formed plates MP 99° to 102°C.
Therapeutic Function
Progestin
DIMETHISTERONE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Shaanxi Dideu Medichem Co. Ltd | +86-029-89586680 +86-18192503167 | 1026@dideu.com | China | 8232 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd | 17691182729 18161915376 | 1046@dideu.com | China | 10010 | 58 |
Shanghai Xx-lab New Materials Co., Ltd | 13585834793 | xx_lab@126.com | China | 1428 | 58 |