ChemicalBook >> CAS DataBase List >>(R)-1-N-Boc-2-(hydroxymethyl)piperazine
(R)-1-N-Boc-2-(hydroxymethyl)piperazine
- CAS No.
- 169448-87-7
- Chemical Name:
- (R)-1-N-Boc-2-(hydroxymethyl)piperazine
- Synonyms
- Nicotinamide Impurity 202;(R)-1-Boc-2-Hydroxymethyl-piperazine;(R)-1-Boc-2-(hyroxyMethyl)piperazine;(R)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE HCl;(S)-1-Boc-2-Hydroxymethyl-piperazine ,98%;(R)-1-Boc-2-Hydroxymethyl-piperazine ,98%;(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate;tert-butyl (R)-2-(hydroxymethyl)piperazine-1-carboxylate;tert-Butyl (2R)-2-(hydroxymethyl)piperazin-1-carboxylate;tert-Butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
- CBNumber:
- CB8948025
- Molecular Formula:
- C10H20N2O3
- Molecular Weight:
- 216.28
- MDL Number:
- MFCD07772092
- MOL File:
- 169448-87-7.mol
- MSDS File:
- SDS
Last updated:2023-10-18 13:30:40
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H332-H335 |
| Precautionary statements | P261-P280-P305+P351+P338 |
| HS Code | 2933599590 |
(R)-1-N-Boc-2-(hydroxymethyl)piperazine price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| ChemScene | CS-D0658 | (R)-1-Boc-2-Hydroxymethyl-piperazine ≥97.0% | 169448-87-7 | 250mg | $50 | 2021-12-16 | Buy |
| ChemScene | CS-D0658 | (R)-1-Boc-2-Hydroxymethyl-piperazine ≥97.0% | 169448-87-7 | 1g | $87 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB140933 | (R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate | 169448-87-7 | 250mg | $100 | 2021-12-16 | Buy |
| Activate Scientific | AS3136 | (R)-1-Boc-2-(Hydroxymethyl)piperazine 97+% ee | 169448-87-7 | 1g | $146 | 2021-12-16 | Buy |
| Biosynth Carbosynth | FB140933 | (R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate | 169448-87-7 | 500mg | $160 | 2021-12-16 | Buy |
(R)-1-N-Boc-2-(hydroxymethyl)piperazine Chemical Properties,Uses,Production
Uses
(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate is used in preparation of novel substituted quinoline-8-carbonitrile derivatives with androgen receptor degradation activity and uses thereof.
Synthesis
Lithium aluminum hydride (1M in THF, 26 ml) was added to a solution of L-TERT- butyl 2-methyl (2R)-piperazine-1, 2-dicarboxylate (2. 55 g) in THF (70 ml) at-40°C, and then the reaction was warmed to room temperature. After stirring for 1 h, this reaction system was cooled to 0°C and quenched by sequential addition of water (1 ml), sodium hydroxide (2N, 1 ml), and then water (2 ml). The resulting slurry was filtered and concentrated in vacuo to give (R)-1-N-Boc-2-(hydroxymethyl)piperazine.
Synthesis of (R)-1-N-Boc-2-(hydroxymethyl)piperazine from (R)-N-Boc-piperazine-2-carboxylic acid methyl ester
(R)-1-N-Boc-2-(hydroxymethyl)piperazine Preparation Products And Raw materials
Global( 124)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Boc Chemical Co., Ltd. | 021-34975602; +8618721111801 | shangli@bocchem.com | China | 138 | 58 |
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49390 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
| SIMAGCHEM CORP | +86-13806087780 | sale@simagchem.com | China | 17367 | 58 |
View Lastest Price from (R)-1-N-Boc-2-(hydroxymethyl)piperazine manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2019-12-27 | (R)-1-N-Boc-2-(hydroxymethyl)piperazine
169448-87-7
|
US $6.60 / KG | 1KG | 97%-99% | 1kg-1000kg | Career Henan Chemical Co |
-
- (R)-1-N-Boc-2-(hydroxymethyl)piperazine
169448-87-7
- US $6.60 / KG
- 97%-99%
- Career Henan Chemical Co
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1of4
(R)-1-Boc-2-Hydroxymethyl-piperazine
1-Piperazinecarboxylic acid, 2-(hydroxymethyl)-, 1,1-dimethylethyl ester, (2R)-
tert-butyl (R)-2-(hydroxymethyl)piperazine-1-carboxylate
(R)-1-N-BOC-2-HYDROXYMETHYLPIPERAZINE HCl
2-Methyl-2-propanyl(2R)-2-(hydroxymethyl)-1-piperazinecarboxylate
(R)-tert-Butyl 2-(hydroxymethyl)piperazine-1-carboxylate
(R)-1-Boc-2-Hydroxymethyl-piperazine ,98%
(S)-1-Boc-2-Hydroxymethyl-piperazine ,98%
tert-Butyl (2R)-2-(hydroxymethyl)piperazine-1-carboxylate
(R)-1-Boc-2-(hyroxyMethyl)piperazine
(R)-1-N-Boc-2-(hydroxymethyl)piperazine###(R)-2-HYDROXYMETHYL-PIPERAZINE-1-CARBOXYLIC ACID TERT-BUTYL ESTER
(2R)-2-(hydroxymethyl)-1-Piperazinecarboxylic acid tert-butyl ester
tert-Butyl (2R)-2-(hydroxymethyl)piperazin-1-carboxylate
Nicotinamide Impurity 202
169448-87-7
16944-87-7
169448-87-8
Piperaizine