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DONITRIPTAN
- CAS No.
- 170912-52-4
- Chemical Name:
- DONITRIPTAN
- Synonyms
- DONITRIPTAN;DONITRIPTANUM;Donitriptan hydrochloride;4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]piperazin-1-yl]benzonitrile;Benzonitrile, 4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]-1-piperazinyl]-;1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)-piperazinehydrochloride;5-hydroxytryptamine Receptor,Donitriptan,Serotonin Receptor,Inhibitor,inhibit,5-HT Receptor
- CBNumber:
- CB92451001
- Molecular Formula:
- C23H25N5O2
- Molecular Weight:
- 403.48
- MDL Number:
- MFCD09832566
- MOL File:
- 170912-52-4.mol
- MSDS File:
- SDS
Last updated:2023-09-04 15:51:00
| Boiling point | 727.1±60.0 °C(Predicted) |
|---|---|
| Density | 1.32±0.1 g/cm3(Predicted) |
| storage temp. | Desiccate at RT |
| solubility | Soluble in DMSO |
| pka | 16.72±0.30(Predicted) |
| FDA UNII | 70968BVH2J |
DONITRIPTAN price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Usbiological | 255184 | Donitriptan hydrochloride | 170912-52-4 | 10mg | $409 | 2021-12-16 | Buy |
| ChemScene | CS-0025002 | Donitriptan | 170912-52-4 | 25mg | $550 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000403 | DONITRIPTAN 95.00% | 170912-52-4 | 10MG | $721.59 | 2021-12-16 | Buy |
| ChemScene | CS-0025002 | Donitriptan | 170912-52-4 | 50mg | $900 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | INB0000403 | DONITRIPTAN 95.00% | 170912-52-4 | 50MG | $1327.97 | 2021-12-16 | Buy |
DONITRIPTAN Chemical Properties,Uses,Production
Uses
A novel 5-hydroxytryptamine (5-HT) derivative with potent, selective, and unique high intrinsic activity at 5-HT1B/1D receptors in models relevant to migraine. An antimigraine agent.
Biological Activity
Brain penetrant 5-HT 1B/1D agonist (pK i values are 9.3 and 9.4 for 5-HT 1D and 5-HT 1B respectively). Inhibits capsaicin-induced external carotid vasodilation and produces selective carotid vasoconstriction in various animal species. Displays antimigraine activity.
DONITRIPTAN Preparation Products And Raw materials
Raw materials
Preparation Products
DONITRIPTAN Suppliers
Global( 21)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| 3B Pharmachem (Wuhan) International Co.,Ltd. | 821-50328103-801 18930552037 | 3bsc@sina.com | China | 15848 | 69 |
| Beijing HuaMeiHuLiBiological Chemical | 010-56205725 | waley188@sohu.com | China | 12338 | 58 |
| EMMX Biotechnology LLC | 888-539-0666 | info@emmx.com | United States | 8449 | 60 |
| Shanghai Han-Xiang Chemical Co., Ltd. | 15971444841 | amber@biochempartner.com | China | 3063 | 58 |
| Fan De(Beijing) Biotechnology Co., Ltd. | 15911056312 | liming@bio-fount.com | China | 9730 | 58 |
| cjbscvictory | 13348960310 13348960310 | 3003867561@qq.com | China | 9946 | 58 |
| Beijing Jin Ming Biotechnology Co., Ltd. | 010-60605840 15801484223 | psaitong@jm-bio.com | China | 29834 | 58 |
| Kaifeng Mingren Pharmaceutical Co.,LTD | 0371-65741762 | sales@hasunny.com | China | 2380 | 58 |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24131 | 58 |
170912-52-4(DONITRIPTAN)Related Search:
DONITRIPTAN
1-[[[3-(2-Aminoethyl)-1H-indol-5-yl]oxy]acetyl]-4-(4-cyanophenyl)-piperazinehydrochloride
Donitriptan hydrochloride
DONITRIPTANUM
4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]piperazin-1-yl]benzonitrile
Benzonitrile, 4-[4-[2-[[3-(2-aminoethyl)-1H-indol-5-yl]oxy]acetyl]-1-piperazinyl]-
5-hydroxytryptamine Receptor,Donitriptan,Serotonin Receptor,Inhibitor,inhibit,5-HT Receptor
170912-52-4