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CTOP
- CAS No.
- 103429-31-8
- Chemical Name:
- CTOP
- Synonyms
- NTB;CTOP;NALTRIBEN;threoninamide;CYS2,TYR3,ORN5,PEN7-AMIDE;M.W. 1062.26 C50H67N11O11S2;(Tyr3,Orn5,Pen7)-Octreotate amide;Cys2, Tyr3, Orn5, Pen7 amide - CTOP;DPHE-CYS-TYR-DTRP-ORN-THR-PEN-THR-OL;D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2
- CBNumber:
- CB9260913
- Molecular Formula:
- C50H67N11O11S2
- Molecular Weight:
- 1062.26
- MDL Number:
- MFCD00076708
- MOL File:
- 103429-31-8.mol
Last updated:2023-06-30 15:45:59
Boiling point | 1491.2±65.0 °C(Predicted) |
---|---|
Density | 1.42±0.1 g/cm3(Predicted) |
RTECS | XO8578200 |
storage temp. | -20°C |
form | Powder |
pka | 9.90±0.15(Predicted) |
Water Solubility | Soluble to 1 mg/ml in water |
FDA UNII | G5H9PK5HEK |
CTOP price More Price(13)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | P5296 | CTOP ≥97% (HPLC) | 103429-31-8 | 1mg | $274 | 2024-03-01 | Buy |
Alfa Aesar | J66263 | CTOP | 103429-31-8 | 1mg | $122 | 2021-12-16 | Buy |
Alfa Aesar | J66263 | CTOP | 103429-31-8 | 5mg | $441 | 2021-12-16 | Buy |
Tocris | 1578 | CTOP | 103429-31-8 | 1 | $195 | 2021-12-16 | Buy |
TRC | C800010 | CTOP | 103429-31-8 | 1mg | $195 | 2021-12-16 | Buy |
CTOP Chemical Properties,Uses,Production
Uses
CTOP is a μ-opioid receptor antagonist which has been shown to regulate behaviour and expression in rats. An endogenous opioid peptide which may also be used in the treatment of pain through improved morphine tolerance via blocking of mTOR.
Uses
CTOP has been used:
- to study the anxiogenic effects induced by CTOP in mice and rat.
- to study the effect of μ-opioid antagonist, CTOP on the bovine milk-derived LF (BLF)-induced analgesia.
- to determine whether μ-opioid receptors act cooperatively with 5-hydroxytryptamine (5-HT1A) receptors to regulate the behaviors generated in the elevated T-maze (ETM).
General Description
D-Pen-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (CTOP) is a selective cyclic μ-opioid receptor antagonist.
Biochem/physiol Actions
Selective ligand for μ-opioid receptors.
storage
Store at -20°C
CTOP Preparation Products And Raw materials
Raw materials
Preparation Products
CTOP Suppliers
Global( 93)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18628 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10311 | 58 |
BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
Shanghai Longyu Biotechnology Co., Ltd. | +8619521488211 | info@longyupharma.com | China | 2534 | 58 |
Cellmano Biotech Limited | 0551-65326643 18156095617 | info@cellmano.com | China | 999 | 58 |
career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29821 | 58 |
Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10522 | 58 |
Hangzhou Go Top Peptide Biotech | 0571-88211921 | sales1@gotopbio.com | CHINA | 2609 | 58 |
Alfa Chemistry | Info@alfa-chemistry.com | United States | 24072 | 58 | |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3581 | 58 |
103429-31-8(CTOP)Related Search:
L-Threoninamide monohydrochloride ,L-Threoninamide HCl,L-THREONINAMIDE HYDROCHLORIDE
3-(2-Naphthalenyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide cyclic (2-7)-disulfide
N-Carbobenzyloxy-L-threoninamide,N2-(Benzyloxycarbonyl)-L-threoninamide,Z-L-THREONINAMIDE,N-Benzyloxycarbonyl-L-Threoninamide,CBZ-L-THREONINAMIDE
isopropyl methyl disulphide
L-Penicillamine
Z-L-THREONINAMIDE,CBZ-L-THREONINAMIDE
CTAP
CTOP
L-Threoninamide, D-phenylalanyl-L-cycteingyl-L-phenylalanyl-D-tryptoph yl-L-lysyl-L-threonyl-L-cysteinyl-, cyclic (2-7)-disulfide
L-Threoninamide
n-acetyl-n-methyl-l-isoleucyl-l-isoleucyl-n-[(1s)-3-methyl-1-[[(2r)-2-methyloxiranyl]carbonyl]butyl]-l-threoninamide
technetium Tc 99m dioxo-1-(alanyl-seryl-threonyl-theonyl-threonyl-asparaginyl-tyrosyl-threoninamide)cyclam
phenylalanyl--cysteinyl-tyrosyl-tryptophyl-arginyl-penicillaminyl-threoninamide
N-Hydroxy-L-threoninamide
phenylalanyl-chlorophenylalanyl-tyrosyl-tryptophyl-lysyl-valyl-phenylalanyl-threoninamide
1of4
threoninamide
NALTRIBEN
NTB
D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR AMIDE
D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2
DPHE-CYS-TYR-DTRP-ORN-THR-PEN-THR-OL
CTOP
CYS2,TYR3,ORN5,PEN7-AMIDE
[CYS2, TYR3, ORN5, PEN7]-SOMATOSTATIN 14 (7-14), AMIDE
H-D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2
H-D-PHE-CYS-TYR-D-TRP-ORN-THR-PEN-THR-NH2 (DISULFIDE BRIDGE: 2-7)
FCYW(ORN)T(PEN)T-NH2 (DISULFIDE BRIDGE: 2-7)
phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide
H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2, (Disulfide bond between Cys2 and Pen7)
M.W. 1062.26 C50H67N11O11S2
D-Phe-L-Cys(1)-L-Tyr-D-Trp-L-Orn-L-Thr-3-Mercapto(1)-L-Val-L-Thr-NH2
D-Phe-L-Cys(1)-L-Tyr-D-Trp-L-Orn-L-Thr-L-Pen(1)-L-Thr-NH2
[Cys2, Tyr3, Orn5, Pen7-amide]-Somatostatin 14 (7-14)
Cys2, Tyr3, Orn5, Pen7 amide - CTOP
CTOP, (Tyr3,Orn5,Pen7)-Octreotate aMide
(Tyr3,Orn5,Pen7)-Octreotate amide
phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)
H-D-Phe-Cys-Tyr-D-Trp-Orn-Thr-Pen-Thr-NH2 (Disulfide bond)
L-Threoninamide, D-phenylalanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-ornithyl-L-threonyl-3-mercapto-L-valyl-, cyclic (2→7)-disulfide
Cys2, Tyr3, Orn5, Pen7-NH2]-Somatostatin14(7-14)
103429-31-8
C50H67N11O11S2
Opioid Peptides
Other Opioid Peptides
Peptides
BioChemical
Biochemicals and Reagents
Amino Acids and Peptides
peptide
Neuropeptides
Opioid Peptides
Other Opioid Peptides
Other Opioid PeptidesPeptides for Cell Biology
Opioid receptor and opioid-like receptor