Hyperforin . DCHA
- CAS No.
- 238074-03-8
- Chemical Name:
- Hyperforin . DCHA
- Synonyms
- Hyp-DCHA;C47H75NO4;Hyperforin . DCHA;Hyperforin (dicylcohexylammonium) salt;Hyperforin (stable Dicyclohexylammonium salt);Hyperforin / AdhyperforinDicyclohexylammonium salt (4:1);Hyperforin (dicyclohexylammonium) salt analytical standard;N-cyclohexylcyclohexanamine,(1R,5R,6R,7S)-2-hydroxy-6-methyl-1,3,7-tris(3-methylbut-2-enyl)-6-(4-methylpent-3-enyl)-5-(2-methylpropanoyl)bicyclo[3.3.1]non-2-ene-4,9-dione
- CBNumber:
- CB92650749
- Molecular Formula:
- C47H75NO4
- Molecular Weight:
- 718.12
- MDL Number:
- MFCD04000098
- MOL File:
- 238074-03-8.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |    GHS05,GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H302-H314-H400 | |||||||||
| Precautionary statements | P260-P273-P280-P301+P312-P303+P361+P353-P305+P351+P338 | |||||||||
| Hazard Codes | C,N | |||||||||
| Risk Statements | 22-34-50/53 | |||||||||
| Safety Statements | 26-36/37/39-45-60-61 | |||||||||
| RIDADR | UN 1759 8 / PGIII | |||||||||
| WGK Germany | 3 | |||||||||
| NFPA 704 |
|
Hyperforin . DCHA price More Price(15)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | H1792 | Hyperforin (dicyclohexylammonium) salt | 238074-03-8 | 1mg | $353 | 2024-03-01 | Buy |
| Sigma-Aldrich | 42891 | Hyperforin (dicyclohexylammonium) salt analytical standard | 238074-03-8 | 5mg | $570 | 2022-05-15 | Buy |
| Cayman Chemical | 19572 | Hyperforin (dicyclohexylammonium salt) ≥97% | 238074-03-8 | 500μg | $134 | 2024-03-01 | Buy |
| Cayman Chemical | 19572 | Hyperforin (dicyclohexylammonium salt) ≥97% | 238074-03-8 | 1mg | $201 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHL89225 | Hyperforin (stable Dicyclohexylammonium salt) phyproof? Reference Substance | 238074-03-8 | 10mg | $1000 | 2024-03-01 | Buy |
Hyperforin . DCHA Chemical Properties,Uses,Production
Description
Hyperforin is a natural activator of the steroid X receptor (active at 0.1 to 0.5 μg/ml) and inhibitor of several cytochrome P450 (CYP) isoforms (IC50 = 10 μg/ml for CYP2D6). It can also inhibit microsomal prostaglandin E2 synthase-1 (mPGES-1; IC50 = 1 μM), 5-lipoxygenase activating protein, and sirtuins.
Uses
Hyperforin Dicyclohexylammonium Salt is an inhibitor of monoamine uptake and TRPC6 agonist.
General Description
This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Biochem/physiol Actions
Stable salt of hyperforin. Hyperforin is believed to be the primary active constituent responsible for the antidepressant and anxiolytic properties of the extracts of St. John′s wort. It acts as a reuptake inhibitor of monoamines, including serotonin, norepinephrine, dopamine, and of GABA and glutamate by activating the transient receptor potential ion channel TRPC6. Activation of TRPC6 induces the entry of sodium and calcium into the cell which causes inhibition of monoamine reuptake. It also is an activator of the pregnane X receptor (PXR), which serves as a key regulator of CYP3A4 transcription, a member of the cytochrome (CYP) P450 enzyme system. Recent studies have found other neurological effects, effects on inflammation, as well as antibacterial, antitumoral and antiangiogenic effects.
storage
+4°C
Hyperforin . DCHA Preparation Products And Raw materials
Raw materials
Preparation Products
Hyperforin . DCHA Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Chengdu Greenpure Biopharma CO.,Ltd | +8618283602253 | jancyzheng@gcgreenpure.com | China | 952 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Aktin Chemicals, Inc. | 028-85159085 | info@aktinchem.com | CHINA | 1025 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| ShangHai YuanYe Biotechnology Co., Ltd. | 021-61312847 13636370518 | shyysw007@163.com | China | 4941 | 60 |
| Chengdu Biopurify Phytochemicals Ltd. | +86-028-82633397 18982077548 | cwb1@biopurify.cn | China | 2376 | 60 |
| Shanghai Tauto Biotech Co., Ltd. | 021-51320588 | tauto@tautobiotech.com | China | 3989 | 66 |
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |