ChemicalBook >> CAS DataBase List >>SGI 7079
SGI 7079
- CAS No.
- 1239875-86-5
- Chemical Name:
- SGI 7079
- Synonyms
- CS-2333;SGI 7079;SGI-7079 /SGI7079;SGI-7079;SGI 7079;SGI7079;Tyro3,inhibit,SGI 7079,Inhibitor,Axl,SGI-7079,Mer,TAM Receptor,SGI7079;3-[2-[[3-Fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]benzeneacetonitrile;Benzeneacetonitrile, 3-[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-;2-(3-(2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile
- CBNumber:
- CB92717503
- Molecular Formula:
- C26H26FN7
- Molecular Weight:
- 455.53
- MDL Number:
- MFCD28963942
- MOL File:
- 1239875-86-5.mol
- MSDS File:
- SDS
Last updated:2023-06-08 09:03:09
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312-P330-P302+P352-P321-P304+P340-P305+P351+P338-P332+P313-P362+P364-P337+P313-P403+P233-P405-P501 | |||||||||
| NFPA 704 |
|
SGI 7079 price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 20111 | SGI-7079 ≥98% | 1239875-86-5 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 20111 | SGI-7079 ≥98% | 1239875-86-5 | 5mg | $131 | 2024-03-01 | Buy |
| Cayman Chemical | 20111 | SGI-7079 ≥98% | 1239875-86-5 | 10mg | $243 | 2024-03-01 | Buy |
| Cayman Chemical | 20111 | SGI-7079 ≥98% | 1239875-86-5 | 25mg | $456 | 2024-03-01 | Buy |
| TRC | F597800 | 3-[2-[[3-Fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]benzeneacetonitrile | 1239875-86-5 | 25mg | $295 | 2021-12-16 | Buy |
SGI 7079 Chemical Properties,Uses,Production
Description
SGI-7079 is an inhibitor of the receptor tyrosine kinase Axl. It inhibits proliferation of inflammatory breast cancer cells (IC50s = 0.43 and 0.15 μM for SUM149 and KPL-4 cells, respectively), decreases invasion, and halts the cell cycle in the G1 phase. SGI-7079 synergistically increases the potency of erlotinib on EGFR inhibition. In a mouse xenograft model of non-small cell lung cancer, SGI-7079 dose-dependently inhibits tumor growth, an effect that is greater when used in combination with erlotinib.
Uses
3-[2-[[3-Fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]benzeneacetonitrile is an anticancer agent and a selective Axl inhibitor.
SGI 7079 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 63)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32715 | 60 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| ShenZhen Trendseen Biological Technology Co.,Ltd. | 13417589054 | trendseenbio@gmail.com | China | 11681 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Wuhan Jingkang en Biomedical Technology Co., Ltd | +8613720134139 | orders@jknbiochem.com | China | 4691 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
1239875-86-5(SGI 7079)Related Search:
1of2
3-[2-[[3-Fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]benzeneacetonitrile
SGI 7079
SGI-7079 /SGI7079
2-(3-(2-((3-Fluoro-4-(4-methylpiperazin-1-yl)phenyl)amino)-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)phenyl)acetonitrile
SGI-7079;SGI 7079;SGI7079
CS-2333
Benzeneacetonitrile, 3-[2-[[3-fluoro-4-(4-methyl-1-piperazinyl)phenyl]amino]-5-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl]-
Tyro3,inhibit,SGI 7079,Inhibitor,Axl,SGI-7079,Mer,TAM Receptor,SGI7079
1239875-86-5
C26H26FN7