ChemicalBook >> CAS DataBase List >>(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride structure

CAS No.: 149690-12-0

Chemical Name:: (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride

Synonyms: Sacubitril Impurity 9 HCl;AHU09;LCZ698;LCZ696-5;LCZ696M-01;4S)-ethyl 5-([1;LCZ-696 Impurity 34;LCZ696 Intermediate2;LCZ-696-005-2R4S-HCl;LCZ696 impurities122

CBNumber:: CB92723689

Molecular Formula:: C20H26ClNO2

Molecular Weight:: 347.88

MDL Number:: MFCD27955983

MOL File:: 149690-12-0.mol

Last updated:2024-04-25 13:42:50

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(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Properties

Melting point	155 - 162°C
storage temp.	under inert gas (nitrogen or Argon) at 2-8°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
color	White to Off-White
Stability	Hygroscopic
InChI	InChI=1/C20H25NO2.ClH/c1-3-23-20(22)15(2)13-19(21)14-16-9-11-18(12-10-16)17-7-5-4-6-8-17;/h4-12,15,19H,3,13-14,21H2,1-2H3;1H/t15-,19+;/s3
InChIKey	MYJTZLYRAWUSLB-MTPCZXHRNA-N
SMILES	C(C1C=CC(C2C=CC=CC=2)=CC=1)[C@@H](N)C[C@@H](C)C(=O)OCC.Cl \|&1:13,16,r\|

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319-H335
Precautionary statements	P261-P305+P351+P338

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride price More Price(19)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A601540	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicAcidEthylEsterHydrochloride	149690-12-0	50mg	$95	2021-12-16	Buy
AK Scientific	2498DC	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride	149690-12-0	25g	$870	2021-12-16	Buy
Ambeed	A249066	(2R,4S)-Ethyl5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95%	149690-12-0	100g	$1192	2021-12-16	Buy
Chemenu	CM244548	(2R,4S)-Ethyl5-([1,1''-biphenyl]-4-yl)-4-amino-2-methylpentanoatehydrochloride 95+%	149690-12-0	1000g	$1748	2021-12-16	Buy
Labseeker	SC-94988	(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoicacidethylesterhydrochloride 98	149690-12-0	1kg	$21666	2021-12-16	Buy

Product number	Packaging	Price	Buy
A601540	50mg	$95	Buy
2498DC	25g	$870	Buy
A249066	100g	$1192	Buy
CM244548	1000g	$1748	Buy
SC-94988	1kg	$21666	Buy

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Chemical Properties,Uses,Production

Uses

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is used as a reagent in the synthesis of LCZ696, an angiotensin II receptor and neprilysin receptor dual inhibitor. (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride is also used as a reagent in the preparation of novel NEP inhibitor prodrugs for the treatment of hypertension and cardiovascular diseases.

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Sacubitril Sodium

(2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride Suppliers

Global( 216)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ChemExpress	+86-021-58950125	info@chemexpress.com	China	557	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Jinan Finer Chemical Co., Ltd	+86-531-88989536 +86-15508631887	sales@finerchem.com	China	2967	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
HubeiwidelychemicaltechnologyCo.,Ltd	18627774460	faith@widelychemical.com	CHINA	742	58

Supplier	Advantage
ChemExpress	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Jinan Finer Chemical Co., Ltd	58
Accela ChemBio Inc.	58
HubeiwidelychemicaltechnologyCo.,Ltd	58

View Lastest Price from (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-04-25	LCZ696（valsartan + sacubitril） impurity 55(Hydrochloride) 149690-12-0	US $0.00-0.00 / mg	10mg	0.98	10g	ShenZhen H&D Pharmaceutical Technology Co., LTD
	2019-07-06	(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate 149690-12-0	US $100.00 / KG	1KG	98%	100KG	Career Henan Chemical Co

LCZ696（valsartan + sacubitril） impurity 55(Hydrochloride)
149690-12-0
US $0.00-0.00 / mg
0.98
ShenZhen H&D Pharmaceutical Technology Co., LTD

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate
149690-12-0
US $100.00 / KG
98%
Career Henan Chemical Co

149690-12-0((2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic Acid Ethyl Ester Hydrochloride)Related Search:

Sacubitril Impurity 7 N-[2’-(1H-tetrazol-5-yl)biphenyl-4-yl methyl]-N-Valeryl-(L)-Valine benzyl ester (2S,4S)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid LCZ Impurity (S)-5-[(Biphenyl-4-yl)carbonyl]pyrrolidin-2-one

2-Pyrrolidinone, 5-([1,1'-biphenyl]-4-ylMethyl)-3-Methyl-, (3R,5S)- Sacubitril Impurity 72 (S)-5-[(Biphenyl-4-yl)methyl]-1-(2,2-dimethylpropionyl)pyrrolidin-2-one (R,E)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-((tert-butoxycarbonyl)aMino)-2-Methylpent-2-enoate ((R)-2-biphenyl-4-yl-1-forMylethyl)carbaMic acid t-butyl ester

LCZ696 interMediate (2R,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid Ethyl (2R,4S)-4-([1,1'-biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoate Valsartan AHU-377 (heMicalciuM salt)

(2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-4-(4-ethoxy-4-oxobutanamido)-2-methylbutanoic acid (2S,4R)-5-(Biphenyl-4-yl)-4-[(tert-butoxycarbonyl)amino]-2-methylpentanoic acid (2R,4S)-4-([1,1'-Biphenyl]-4-ylmethyl)-2-methyl-4-(2,5-dioxopyrrolidin-1-yl)butanoic acid

1of4

(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate HCl LCZ696 Intermediate2 LCZ698 [1,1'-Biphenyl]-4-pentanoic acid, γ-amino-α-methyl-, ethyl ester, hydrochloride (1:1), (αR,γS)- (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-aMino-2-Methylpentanoate hydrochloride (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride (1:1) (2R, 4S) - ethyl 5- ([1,1'- biphenyl]-4- group) -4- amino -2- methyl valerate hydrochloride acubitril Impurity 9 HCl (2R,4S)-4-Amino-5-(biphenyl-4-yl)-2-methylpentanoic acid ethyl ester hydrochloride149690-12-0 LCZ-696 Impurity 34 AHU09 LCZ-696-005-2R4S-HCl Sacubitril Impurity 26 LCZ696M-01 LCZ696(valsartan + sacubitril) impurity 5 (2R,4S)-Ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate HCl salt 1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 4S)-ethyl 5-([1 LCZ696-5 Ethyl (2R,4S)-5-(4-Biphenylyl)-4-amino-2-methylpentanoate Hydrochloride 1,1'-Biphenyl]-4-pentanoicacid,γ-amino-α-methyl-,ethylester,(αR,γS)-,hydrochloride(1:1) ethyl (2R,4S)-5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpenta... LCZ696 impurities122 ethyl (2R,4S)-4-amino-5-{[1,1'-biphenyl]-4-yl}-2-methylp entanoate hydrochloride Sacubitril Impurity 9 HCl (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino Benzene,1-methoxy-2-methyl-5-nitro- (2R,4S)-Ethyl 4-amino-5-(biphenyl -4-yl)-2-methylpentanoate hydrochloride Sacubitril Impurity 35 HCl Sacubitril Impurity 26 Hydrochloride SACUBITRIL SAV-3 (AMINE ESTER) Salcubatra calcium impurity D Olaquindox Impurity 4 LCZ696 Intermediate 3 Sacubitril Impurity 5 HCl LCZ-696 Impurity 5 HCl Sacubitril intermediates(2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride Sacubitril Impurity 3 HCl LCZ696（valsartan + sacubitril） impurity 55(Hydrochloride) (2R,4S)-ethyl 5-([1,1'-biphenyl]-4-yl)-4-amino-2-methylpentanoate hydrochloride 149690-12-0 LCZ696 149690-12-0