Bromo-PEG2-azide
- CAS No.
- 530151-56-5
- Chemical Name:
- Bromo-PEG2-azide
- Synonyms
- N3-PEG2-Br;Br-PEG2-N3;Azido-PEG2-Br;N3-PEG2-CH2CH2Br;Bromo-PEG2-azide;Azido-PEG3-bromide;Bromo-PEG2-C2-azide;1-(2-Azidoethoxy)-2-(2-bromoethoxy)ethane;N3-PEG2-CH2CH2Br/Ethane, 1-(2-azidoethoxy)-2-(2-bromoethoxy)-
- CBNumber:
- CB93062439
- Molecular Formula:
- C6H12BrN3O2
- Molecular Weight:
- 238.08238
- MDL Number:
- MFCD25424115
- MOL File:
- 530151-56-5.mol
Bromo-PEG2-azide price
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
BroadPharm | BP-21716 | Bromo-PEG2-azide 98% | 530151-56-5 | 500mg | $480 | 2021-12-16 | Buy |
Activate Scientific | AS107899 | N3-PEG2-CH2CH2Br 97% | 530151-56-5 | 1g | $618 | 2021-12-16 | Buy |
BroadPharm | BP-21716 | Bromo-PEG2-azide 98% | 530151-56-5 | 1g | $680 | 2021-12-16 | Buy |
Bromo-PEG2-azide Chemical Properties,Uses,Production
Description
Bromo-PEG2-azide is a heterobifunctional crosslinking reagent.. The azide group can react with alkyne, BCN, DBCO via Click Chemistry. The bromide (Br) is a good leaving group for nucleophilic substitution.
Biological Activity
Bromo-PEG2-C2-azide is a non-degradable ADC linker for the synthesis of antibody drug conjugates (ADCs),it is also a PEG-based PROTAC linker that can be used for PROTAC synthesis.
in vitro
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
target
Non-cleavable < span> | PEGs
|
Bromo-PEG2-azide Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
Wuhan Borenpharm Co., Ltd | 027-65563561 18717150066 | 3207347307@qq.com | CHINA | 1238 | 58 |
Hangzhou Huarong Pharm Co., Ltd. | 571-86758373 +8613588754946 | sales@huarongpharm.com | CHINA | 3149 | 58 |
Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19915 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503259 +86-19930503259 | cherry@crovellbio.com | China | 18456 | 58 |
Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
View Lastest Price from Bromo-PEG2-azide manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-03-24 | Azido-PEG2-Br
530151-56-5
|
US $0.00 / g | 1g | >98.00% | 1g | Xian confluore Biological Technology Co., Ltd. |
- Azido-PEG2-Br
530151-56-5
- US $0.00 / g
- >98.00%
- Xian confluore Biological Technology Co., Ltd.